| WBGene00001501 | SMap | S_parent | Sequence | D1037 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | ftn-2 |
| | | Sequence_name | D1037.3 |
| | | Molecular_name | D1037.3 |
| | | | D1037.3.1 |
| | | | CE20622 |
| | | Other_name | CELE_D1037.3 | Accession_evidence | NDB | BX284601 |
| | | Public_name | ftn-2 |
| | DB_info | Database (12) |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | ftn |
| | Allele (16) |
| | Strain | WBStrain00002965 |
| | | WBStrain00031408 |
| | RNASeq_FPKM (74) |
| | GO_annotation (17) |
| | Ortholog (74) |
| | Paralog | WBGene00001500 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Inparanoid_8 |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | Structured_description | Concise_description | ftn-2 encodes one of two C. elegans ferritin heavy chain homologs; loss of ftn-2 activity via deletion mutation results in slightly lower brood sizes and, under iron stress conditions, slightly faster growth from the L4 to adult stage of development, and slightly reduced lifespan; an ftn-2::gfp reporter fusion is expressed in diverse tissues, including the pharynx, intestine, and hypodermis, and its expression, along with that of ftn-2 mRNA, does not appear to change significantly under iron stress conditions. | Paper_evidence | WBPaper00005703 |
| | | | | | WBPaper00006525 |
| | | | | | WBPaper00024456 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | | WBPerson1823 |
| | | | | | WBPerson567 |
| | | | | Date_last_updated | 10 Mar 2006 00:00:00 |
| | | Automated_description | Enables identical protein binding activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in cytoplasm. Expressed in body wall musculature and hypodermis. Human ortholog(s) of this gene implicated in several diseases, including hemochromatosis type 5; hyperferritinemia-cataract syndrome; and neurodegeneration with brain iron accumulation 3. Is an ortholog of human FTMT (ferritin mitochondrial). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Potential_model | DOID:0111256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) |
| | | DOID:1289 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) |
| | | DOID:0111031 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3976) |
| | | DOID:0080600 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3976,HGNC:3999) |
| | | DOID:0110737 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) |
| | | DOID:679 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) |
| Molecular_info | Corresponding_CDS | D1037.3 |
| | Corresponding_transcript | D1037.3.1 |
| | Other_sequence (155) |
| | Associated_feature (16) |
| Experimental_info | RNAi_result | WBRNAi00089360 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00102059 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00116826 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00033297 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00102060 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00003267 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00069754 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00043364 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00067721 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00089349 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Chronogram1229 |
| | | Expr3081 |
| | | Expr4744 |
| | | Expr5610 |
| | | Expr7855 |
| | | Expr1022759 |
| | | Expr1030901 |
| | | Expr1147349 |
| | | Expr2011914 |
| | | Expr2030151 |
| | Drives_construct | WBCnstr00003471 |
| | | WBCnstr00009029 |
| | | WBCnstr00011121 |
| | | WBCnstr00012954 |
| | | WBCnstr00016205 |
| | | WBCnstr00036907 |
| | Construct_product | WBCnstr00011121 |
| | | WBCnstr00036907 |
| | Antibody | WBAntibody00002946 |
| | Microarray_results (23) |
| | Expression_cluster | WBPaper00029359_1280 |
| | | WBPaper00029359_1304 |
| | | WBPaper00029359_1444 |
| | | WBPaper00029359_1497 |
| | | WBPaper00029359_1504 |
| | | WBPaper00029359_1604 |
| | | WBPaper00031040:TGF-beta_adult_upregulated |
| | | WBPaper00032528:L3_enriched |
| | | WBPaper00033070:Elbe_upregulated |
| | | WBPaper00035269:cde-1_regulated |
| | | WBPaper00037950:all-neurons_L1-larva_expressed |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:hypodermis_embryo_enriched |
| | | WBPaper00037950:hypodermis_embryo_SelectivelyEnriched |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:intestine_embryo_enriched |
| | | WBPaper00037950:intestine_embryo_SelectivelyEnriched |
| | | WBPaper00037950:intestine_L2-larva_expressed |
| | | WBPaper00037950:pharyngeal-muscle_embryo_enriched |
| | | WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038118:stress_upregulated_N2 |
| | | WBPaper00038168:lin-15B(n744)_downregulated |
| | | WBPaper00038213:E.coli(LF82)_24h_upregulated |
| | | WBPaper00038289:oocyte_protein |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray |
| | | WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq |
| | | WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray |
| | | WBPaper00040209:B.thuringiensis_downregulated_MY18 |
| | | WBPaper00040990:PA14_upregulated |
| | | WBPaper00044426:rotenone_24h_upregulated |
| | | WBPaper00044501:gld-1_let-7_regulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044746:aging_upregulated_Day5 |
| | | WBPaper00045050:csr-1(hypomorph)_downregulated |
| | | WBPaper00045314:S.aureus-induced_N2 |
| | | WBPaper00045417:128Q-huntingtin_downreglated |
| | | WBPaper00045420:fertilization_upregulated_transcript |
| | | WBPaper00045521:Spermatogenic |
| | | WBPaper00045774:clk-1_downregulated |
| | | WBPaper00046121:endoderm_unique |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h |
| | | WBPaper00048923:Aging_regulated |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049018:ham-3(RNAi)_downregulated |
| | | WBPaper00049334:CE_intestine_enriched |
| | | WBPaper00049368:daf-2(e1370)_downregulated |
| | | WBPaper00049498:npr-1(ur89)_regulated_3 |
| | | WBPaper00049545:cco-1(RNAi)_downregulated |
| | | WBPaper00049545:jmjd-3.1(+)_downregulated |
| | | WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated |
| | | WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi) |
| | | WBPaper00049942:hsf-1(RNAi)_downregulated |
| | | WBPaper00050448:KGB-1-induced |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C |
| | | WBPaper00050514:CEBP-1_interacting |
| | | WBPaper00050686:glp-1(e2141)_upregulated |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050726:OsmoticStress_regulated_NoFood |
| | | WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:body-muscle_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00050990:seam_expressed |
| | | WBPaper00051039:intestine_enriched |
| | | WBPaper00051245:cytoplasm_specific |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00051245:intestine_nucleus_expressed |
| | | WBPaper00051265:F4_morc-1(tm6048)_downregulated |
| | | WBPaper00052884:emb-4(hc60)_upregulated |
| | | WBPaper00053184:sma-2(rax5)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053295:lin-22(ot267)_downregulated |
| | | WBPaper00053295:lin-22(ot269)_downregulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053321:PGCs_depleted_NuGen |
| | | WBPaper00053388:dauer_regulated_Cluster3 |
| | | WBPaper00053599:female_vs_male_downregulated |
| | | WBPaper00053606:N2_vs_elt-2(ca15)_upregulated |
| | | WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated |
| | | WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated |
| | | WBPaper00055049:S.gordonii_upregulated |
| | | WBPaper00055060:flr-1(RNAi)_upregulated |
| | | WBPaper00055103:thoc-5(wy822)_downregulated |
| | | WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched |
| | | WBPaper00055827:daf-2(e1370)_downregulated |
| | | WBPaper00055941:hif-1(ia4)_upregulated |
| | | WBPaper00056034:pals-25(jy9)_downregulated |
| | | WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047) |
| | | WBPaper00056139:soil-microbiota_upregulated |
| | | WBPaper00056161:male_enriched_siRNA |
| | | WBPaper00056275:P.aeruginosa_downregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1 |
| | | WBPaper00056900:PID-3_interacting |
| | | WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C |
| | | WBPaper00057347:nhr-14(tm1473)_upreglated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058691:set-2(bn129)_upregulated |
| | | WBPaper00058691:sin-3(tm1276)_downregulated |
| | | WBPaper00058711:paraquat_downregulated |
| | | WBPaper00058711:wdr-5(ok1417)_downregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00058969:RIS_depleted |
| | | WBPaper00059027:neuron-synapses_depleted |
| | | WBPaper00059334:SACY-1_interacting |
| | | WBPaper00059356:BAZ-2_SET-6_interacting |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus |
| | | WBPaper00059987:Wounding_upregulated |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi) |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_N2 |
| | | WBPaper00060399:CoCl2_6hr_downregulated_N2 |
| | | WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr |
| | | WBPaper00060458:rnf-5(tm794)_regulated |
| | | WBPaper00060683:hlh-11(ko1)_downregulated |
| | | WBPaper00060909:atfs-1(cmh15)_downregulated |
| | | WBPaper00060911:prx-5(RNAi)_upregulated_mRNA |
| | | WBPaper00061203:let-418(n3536)_upregulated |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061340:Intestine |
| | | WBPaper00061377:MYRF-1_interacting |
| | | WBPaper00061439:unc-30(ok613)_upregulated |
| | | WBPaper00061478:pie-1(ne4433)_upregulated |
| | | WBPaper00061479:hda-1(ne4752)_upregulated |
| | | WBPaper00061479:ubc-9(ne4833)_upregulated |
| | | WBPaper00061527:dhs-28_22199-acs-14 |
| | | WBPaper00061527:R10H10.3-T21H3.1 |
| | | WBPaper00061651:Intestine_enriched |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00064055:trl-1(cas1077)_downregulated_non-starved |
| | | WBPaper00064055:trl-1(cas1077)_downregulated_starved |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated |
| | | WBPaper00064716:paraquat_downregulated |
| | | WBPaper00064727:daf-2(e1370)_upregulated |
| | | WBPaper00064992:Capsaicin_downregulated |
| | | WBPaper00065086:JU1400_N.ausubeli_regulated |
| | | WBPaper00065086:JU1400_N.ferruginous_regulated |
| | | WBPaper00065120:body-muscle-transcriptome |
| | | WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal |
| | | WBPaper00065158:AFD_depleted |
| | | WBPaper00065373:sek-1(km4)_downregulated_Ref |
| | | WBPaper00065392:Lb.delbrueckii_downregulated |
| | | WBPaper00065392:Lb.reuteri_downregulated |
| | | WBPaper00065392:P.pentosaceus_downregulated |
| | | WBPaper00065623:15 |
| | | WBPaper00065835:Day11_vs_Day1_downregulated |
| | | WBPaper00065841:3_1 |
| | | WBPaper00065841:3_2 |
| | | WBPaper00065841:3_4 |
| | | WBPaper00065841:3_5 |
| | | WBPaper00065841:26_2 |
| | | WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein |
| | | WBPaper00065975:P-body_vs_oocyte_depleted |
| | | WBPaper00065975:P-body_vs_WholeAnimal_depleted |
| | | WBPaper00065984:pals-17(syb3980)_downregulated |
| | | WBPaper00065993:glp-1(e2141)_upregulated |
| | | WBPaper00066085:hda-3(ok1991)_upregulated |
| | | cgc4489_group_24 |
| | | WBPaper00005124:cholesterol_10-9M_regulated |
| | | WBPaper00025032:cluster_2 |
| | | WBPaper00025099:MA_specific |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Enriched_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00030839:Embryo_A_Class |
| | | WBPaper00031532:Larva_Pan_Neuronal_Depleted |
| | | WBPaper00032062:age_regulated_genes |
| | | WBPaper00034739:N2lessDR1350 |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00036286:Pattern_I |
| | | WBPaper00037695:WC_5-day |
| | | WBPaper00038231:Cry5B_1.5-fold_downregulated |
| | | WBPaper00038231:Cry5B_2-fold_downregulated |
| | | WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2 |
| | | WBPaper00040823:alg-1(gk214)_upregulated |
| | | WBPaper00040985:AIN-2_asynchronous_intestine |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_EtBr-exposed_51h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_24h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h |
| | | WBPaper00042178:hlh-29(tm284)_upregulated |
| | | WBPaper00045263:0.1mM-paraquat_downregulated |
| | | WBPaper00045673:colistin_upregulated |
| | | WBPaper00045960:L1-L4-lethargus_downregulated |
| | | WBPaper00045960:L4-lethargus_downregulated |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | | WBPaper00055899:nitroguanidine_regulated |
| | | [cgc6390]:Cluster_B |
| | Interaction (202) |
| | WBProcess | WBbiopr:00000039 |
| | | WBbiopr:00000096 |
| Map_info | Map | I | Position | -2.93309 | Error | 0.018064 |
| | Positive | Positive_clone | D1037 | Inferred_automatically | From CDS info |
| | | | | | From sequence, transcript, pseudogene data |
| | Mapping_data | Multi_point | 4327 |
| | | | 4429 |
| | | | 4670 |
| | Pseudo_map_position |
| Reference | WBPaper00005703 |
| | WBPaper00010069 |
| | WBPaper00024456 |
| | WBPaper00028919 |
| | WBPaper00031227 |
| | WBPaper00033213 |
| | WBPaper00033895 |
| | WBPaper00037489 |
| | WBPaper00038213 |
| | WBPaper00038491 |
| | WBPaper00039832 |
| | WBPaper00040073 |
| | WBPaper00040550 |
| | WBPaper00042178 |
| | WBPaper00055090 |
| | WBPaper00059715 |
| | WBPaper00061108 |
| | WBPaper00061547 |
| | WBPaper00064339 |
| | WBPaper00064473 |
| | WBPaper00065176 |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
