WormBase Tree Display for Gene: WBGene00001500
expand all nodes | collapse all nodes | view schema
| WBGene00001500 | SMap | S_parent | Sequence | C54F6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ftn-1 | |||||||
| Sequence_name | C54F6.14 | ||||||||
| Molecular_name | C54F6.14 | ||||||||
| C54F6.14.1 | |||||||||
| CE48091 | |||||||||
| Other_name | CELE_C54F6.14 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | ftn-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ftn | ||||||||
| Allele (31) | |||||||||
| Strain | WBStrain00033278 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (69) | |||||||||
| Paralog | WBGene00001501 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ftn-1 encodes one of two C. elegans ferritin heavy chain homologs; ftn-1 activity is essential for normal lifespan under iron stress conditions and, in addition, has been reported to be essential for embryogenesis; an ftn-1::gfp reporter is expressed in the intestine at all stages of development and its expression, as well as that of ftn-1 mRNA, increases under iron stress conditions and in the background of mutations in the second ferritin-encoding gene, ftn-2. | Paper_evidence | WBPaper00005703 | |||||
| WBPaper00024456 | |||||||||
| WBPaper00024497 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 10 Mar 2006 00:00:00 | ||||||||
| Automated_description | Enables identical protein binding activity. Involved in intracellular iron ion homeostasis. Predicted to be located in cytoplasm. Expressed in intestine and pharyngeal-intestinal valve. Human ortholog(s) of this gene implicated in several diseases, including hemochromatosis type 5; hyperferritinemia-cataract syndrome; and neurodegeneration with brain iron accumulation 3. Is an ortholog of human FTH1 (ferritin heavy chain 1); FTHL17 (ferritin heavy chain like 17); and FTMT (ferritin mitochondrial). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||
| DOID:1289 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||||
| DOID:0111031 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3976) | ||||||
| DOID:0080600 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3976,HGNC:3999) | ||||||
| DOID:0110737 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||||
| DOID:679 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||||
| Molecular_info | Corresponding_CDS | C54F6.14 | |||||||
| Corresponding_transcript | C54F6.14.1 | ||||||||
| Other_sequence (18) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result (19) | ||||||||
| Expr_pattern | Expr3080 | ||||||||
| Expr4745 | |||||||||
| Expr7854 | |||||||||
| Expr9976 | |||||||||
| Expr10814 | |||||||||
| Expr14898 | |||||||||
| Expr1013694 | |||||||||
| Expr1147140 | |||||||||
| Expr2011913 | |||||||||
| Expr2030150 | |||||||||
| Drives_construct (20) | |||||||||
| Construct_product | WBCnstr00011120 | ||||||||
| WBCnstr00014621 | |||||||||
| WBCnstr00036908 | |||||||||
| WBCnstr00041574 | |||||||||
| WBCnstr00042810 | |||||||||
| WBCnstr00042811 | |||||||||
| Antibody | WBAntibody00002946 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (363) | |||||||||
| Interaction (217) | |||||||||
| WBProcess | WBbiopr:00000096 | ||||||||
| Map_info | Map | V | Position | 0.786806 | Error | 0.005591 | |||
| Positive | Positive_clone | C54F6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (42) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
