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WormBase Tree Display for Gene: WBGene00001501

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Name Class

WBGene00001501SMapS_parentSequenceD1037
IdentityVersion1
NameCGC_nameftn-2
Sequence_nameD1037.3
Molecular_nameD1037.3
D1037.3.1
CE20622
Other_nameCELE_D1037.3Accession_evidenceNDBBX284601
Public_nameftn-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classftn
Allele (16)
StrainWBStrain00002965
WBStrain00031408
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (74)
ParalogWBGene00001500Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionftn-2 encodes one of two C. elegans ferritin heavy chain homologs; loss of ftn-2 activity via deletion mutation results in slightly lower brood sizes and, under iron stress conditions, slightly faster growth from the L4 to adult stage of development, and slightly reduced lifespan; an ftn-2::gfp reporter fusion is expressed in diverse tissues, including the pharynx, intestine, and hypodermis, and its expression, along with that of ftn-2 mRNA, does not appear to change significantly under iron stress conditions.Paper_evidenceWBPaper00005703
WBPaper00006525
WBPaper00024456
Curator_confirmedWBPerson1843
WBPerson1823
WBPerson567
Date_last_updated10 Mar 2006 00:00:00
Automated_descriptionEnables identical protein binding activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in cytoplasm. Expressed in body wall musculature and hypodermis. Human ortholog(s) of this gene implicated in several diseases, including hemochromatosis type 5; hyperferritinemia-cataract syndrome; and neurodegeneration with brain iron accumulation 3. Is an ortholog of human FTMT (ferritin mitochondrial).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111256Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3999)
DOID:1289Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3999)
DOID:0111031Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3976)
DOID:0080600Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3976,HGNC:3999)
DOID:0110737Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3999)
DOID:679Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3999)
Molecular_infoCorresponding_CDSD1037.3
Corresponding_transcriptD1037.3.1
Other_sequence (155)
Associated_feature (16)
Experimental_infoRNAi_resultWBRNAi00089360Inferred_automaticallyRNAi_primary
WBRNAi00102059Inferred_automaticallyRNAi_primary
WBRNAi00116826Inferred_automaticallyRNAi_primary
WBRNAi00033297Inferred_automaticallyRNAi_primary
WBRNAi00102060Inferred_automaticallyRNAi_primary
WBRNAi00003267Inferred_automaticallyRNAi_primary
WBRNAi00069754Inferred_automaticallyRNAi_primary
WBRNAi00043364Inferred_automaticallyRNAi_primary
WBRNAi00067721Inferred_automaticallyRNAi_primary
WBRNAi00089349Inferred_automaticallyRNAi_primary
Expr_patternChronogram1229
Expr3081
Expr4744
Expr5610
Expr7855
Expr1022759
Expr1030901
Expr1147349
Expr2011914
Expr2030151
Drives_constructWBCnstr00003471
WBCnstr00009029
WBCnstr00011121
WBCnstr00012954
WBCnstr00016205
WBCnstr00036907
Construct_productWBCnstr00011121
WBCnstr00036907
AntibodyWBAntibody00002946
Microarray_results (23)
Expression_cluster (215)
Interaction (202)
WBProcessWBbiopr:00000039
WBbiopr:00000096
Map_infoMapIPosition-2.93309Error0.018064
PositivePositive_cloneD1037Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4327
4429
4670
Pseudo_map_position
Reference (21)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene