WormBase Tree Display for Gene: WBGene00001501
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| WBGene00001501 | SMap | S_parent | Sequence | D1037 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ftn-2 | |||||||
| Sequence_name | D1037.3 | ||||||||
| Molecular_name | D1037.3 | ||||||||
| D1037.3.1 | |||||||||
| CE20622 | |||||||||
| Other_name | CELE_D1037.3 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | ftn-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ftn | ||||||||
| Allele (16) | |||||||||
| Strain | WBStrain00002965 | ||||||||
| WBStrain00031408 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (74) | |||||||||
| Paralog | WBGene00001500 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ftn-2 encodes one of two C. elegans ferritin heavy chain homologs; loss of ftn-2 activity via deletion mutation results in slightly lower brood sizes and, under iron stress conditions, slightly faster growth from the L4 to adult stage of development, and slightly reduced lifespan; an ftn-2::gfp reporter fusion is expressed in diverse tissues, including the pharynx, intestine, and hypodermis, and its expression, along with that of ftn-2 mRNA, does not appear to change significantly under iron stress conditions. | Paper_evidence | WBPaper00005703 | |||||
| WBPaper00006525 | |||||||||
| WBPaper00024456 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 10 Mar 2006 00:00:00 | ||||||||
| Automated_description | Enables identical protein binding activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in cytoplasm. Expressed in body wall musculature and hypodermis. Human ortholog(s) of this gene implicated in several diseases, including hemochromatosis type 5; hyperferritinemia-cataract syndrome; and neurodegeneration with brain iron accumulation 3. Is an ortholog of human FTMT (ferritin mitochondrial). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||
| DOID:1289 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||||
| DOID:0111031 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3976) | ||||||
| DOID:0080600 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3976,HGNC:3999) | ||||||
| DOID:0110737 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||||
| DOID:679 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||||
| Molecular_info | Corresponding_CDS | D1037.3 | |||||||
| Corresponding_transcript | D1037.3.1 | ||||||||
| Other_sequence (155) | |||||||||
| Associated_feature (16) | |||||||||
| Experimental_info (9) | |||||||||
| Map_info | Map | I | Position | -2.93309 | Error | 0.018064 | |||
| Positive | Positive_clone | D1037 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4327 | |||||||
| 4429 | |||||||||
| 4670 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
