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WormBase Tree Display for Gene: WBGene00017755

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Name Class

WBGene00017755SMapS_parentSequenceF23F12
IdentityVersion2
NameCGC_namezip-8Person_evidenceWBPerson260
WBPerson460
Sequence_nameF23F12.9
Molecular_nameF23F12.9a
F23F12.9a.1
CE01256
F23F12.9b
CE32389
F23F12.9b.1
Other_nameCELE_F23F12.9Accession_evidenceNDBBX284603
Public_namezip-8
DB_infoDatabaseAceViewgene3H569
WormQTLgeneWBGene00017755
WormFluxgeneWBGene00017755
NDBlocus_tagCELE_F23F12.9
PanthergeneCAEEL|WormBase=WBGene00017755|UniProtKB=P46505
familyPTHR23334
NCBIgene175924
RefSeqproteinNM_066025.5
NM_181936.7
SwissProtUniProtAccP46505
UniProt_GCRPUniProtAccP46505
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:59WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
223 Sep 2011 16:44:07WBPerson2970Name_changeCGC_namezip-8
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classzip
Allele (37)
StrainWBStrain00002144
WBStrain00030131
RNASeq_FPKM (74)
GO_annotation00046256
00046257
00046258
00046259
00046260
00046261
00123062
00123063
00123064
Ortholog (21)
ParalogWBGene00016754Caenorhabditis elegansFrom_analysisPanther
WBGene00016997Caenorhabditis elegansFrom_analysisPanther
WBGene00021552Caenorhabditis elegansFrom_analysisPanther
WBGene00019327Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionzip-8 encodes a bZip family transcription factor; the tm721 variation that affects zip-8 has been reported to result in lethality; a zip-8::gfp reporter fusion is expressed in the adult intestine.Paper_evidenceWBPaper00027309
WBPaper00031006
Curator_confirmedWBPerson1843
Date_last_updated20 Feb 2014 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Expressed in intestinal cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF23F12.9a
F23F12.9b
Corresponding_transcriptF23F12.9a.1
F23F12.9b.1
Associated_featureWBsf645270
WBsf978798
WBsf992778
WBsf1015102
WBsf225115
WBsf225116
WBsf225117
WBsf225118
Gene_product_binds (64)
Transcription_factorWBTranscriptionFactor000404
Experimental_infoRNAi_resultWBRNAi00031333Inferred_automaticallyRNAi_primary
WBRNAi00068787Inferred_automaticallyRNAi_primary
WBRNAi00045438Inferred_automaticallyRNAi_primary
WBRNAi00013827Inferred_automaticallyRNAi_primary
WBRNAi00005895Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Drives_constructWBCnstr00002903
WBCnstr00015247
WBCnstr00022349
WBCnstr00027047
Construct_productWBCnstr00016740
WBCnstr00022349
WBCnstr00027047
Microarray_results (29)
Expression_clusterWBPaper00028867:HLH-1_induced_TF
WBPaper00028867:PAL-1_induced_TF
WBPaper00032031:DConiospora_downregulated_cDNA_12h
WBPaper00033065:clk-1(qm30)_upregulated
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00036231:long-telomeres_upregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:coelomocytes_embryo_enriched
WBPaper00037950:coelomocytes_embryo_SelectivelyEnriched
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00042561:smg-2(RNAi)_upregulated
WBPaper00042561:smgl-1(RNAi)_downregulated
WBPaper00044260:1-methylnicotinamide_downregulated
WBPaper00044260:nicotic-acid_downregulated
WBPaper00044316:CH3HgCl_7.5uM_downregulated
WBPaper00044426:rotenone_5day_downregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00045257:bar-1(ga80)_upregulated
WBPaper00045390:ubc-9(RNAi)_downregulated
WBPaper00045417:128Q-huntingtin_upreglated
WBPaper00045420:fertilization_upregulated_transcript
WBPaper00045774:clk-1_upregulated
WBPaper00045861:wdr-5(ok1417)_upregulated
WBPaper00045974:NSM_enriched_totalRNA_tiling
WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00046691:AB_enriched
WBPaper00046805:csr-1(RNAi)_upregulated_Set1
WBPaper00046805:csr-1(RNAi)_upregulated_Set2
WBPaper00048988:neuron_enriched
WBPaper00048988:neuron_expressed
WBPaper00049098:heat-induced_hrde-1(tm1200)
WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
WBPaper00050234:lin-28(RNAi)_upregulated
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050561:indole_10-fold_downregulated
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:body-muscle_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051305:vit-2(ac3)_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(ot269)_upregulated
WBPaper00053318:Aging_upregulated_mRNA_N2
WBPaper00053318:mir-71(n4115)_upregulated_mRNA
WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster2
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00053664:ins-11(tm1053)_upregulated
WBPaper00053810:sod-2(ok1030)_upregulated
WBPaper00053814:15C_downregulated_OP50
WBPaper00053814:15C_downregulated_PY79
WBPaper00054493:hpl-2(tm1489)_downregulated
WBPaper00055013:hmg-3(bar24)_upregulated
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:Allantoin_downregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rapamycin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin-Psora_downregulated
WBPaper00055386:daf-2(e1370)_downregulated
WBPaper00055386:eat-2(ad465)_downregulated
WBPaper00055482:Tunicamycin_upregulated
WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
WBPaper00055971:nhl-2(ok818)_20C_upregulated
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056039:ptl-1(ok621)_upregulated
WBPaper00056039:ptrn-1(tm5597)_upregulated
WBPaper00056139:gut-microbiota_downregulated
WBPaper00056139:soil-microbiota_upregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056167:Cry5B_upregulated
WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056446:hsb-1(cg116)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056809:smn-1(ok355)_upregulated
WBPaper00057006:DietaryRestriction_downregulated
WBPaper00058598:mex-3(eu149)_downregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058691:cfp-1(tm6369)_downregulated
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00058711:paraquat_upregulated
WBPaper00058711:wdr-5(ok1417)_upregulated
WBPaper00058725:sftb-1(cer6)_upregulated
WBPaper00058725:sftb-1(cer39)_upregulated
WBPaper00058958:100mGy-irradiation-72h_upregulated
WBPaper00059027:neuron-synapses_depleted
WBPaper00059224:tph-1(mg280)_upregulated
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059728:5ug_cholesterol_downregulated
WBPaper00059728:20ug_cholesterol_downregulated
WBPaper00059739:hira-1(gk835598)_upregulated_adult
WBPaper00059763:neuron_expressed
WBPaper00059824:rnp-6(dh1127)_regulated_OP50
WBPaper00060445:nfki-1(cer1)_upregulated_L4
WBPaper00060459:bcat-1(RNAi)_downregulated
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:AUA
WBPaper00061340:Ciliated_amphid_neuron
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061424:Diet_MYb120_downregulated
WBPaper00061424:Diet_MYb131_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:mep-1(ne4629)_upregulated
WBPaper00061527:dsh-1_3575-C40A11.4
WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
WBPaper00061853:osm-3(dh441)_upregulated
WBPaper00061853:osm-3(dh441)_upregulated_tunicamycin
WBPaper00061952:daf-18(nr2037)_downregulated
WBPaper00061952:daf-18(yh1)_downregulated
WBPaper00062095:unc-4(e120)_upregulated_VA-neuron
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00062456:doxycycline_downregulated_CB4856_transcript
WBPaper00062497:xpf-1(tm2842)_upregulated
WBPaper00062585:hlh-26(ok1453)_downregulated_E.faecium
WBPaper00062590:Aging_upregulated_neuron
WBPaper00062606:rotenone_upregulated
WBPaper00064122:vulva_transcriptome
WBPaper00064130:Beta-Amyloid_24h_downregulated_mRNA
WBPaper00064156:lipl-4(overexpress)_downregulated
WBPaper00064315:mes-3(bn199)_upregulated_EGCs
WBPaper00064315:mes-4(bn73)_upregulated_EGCs
WBPaper00064494:postdauer_upregulated_WholeAnimal
WBPaper00064716:paraquat_upregulated
WBPaper00064727:daf-2(e1370)_downregulated
WBPaper00064769:him-17(me24)_downregulated
WBPaper00064871:hypoxia_downregulated_F2
WBPaper00064999:miR-229-64-65-66_upregulated
WBPaper00065005:sams-3(RNAi)_upregulated
WBPaper00065005:sams-4(RNAi)_upregulated
WBPaper00065096:25C_vs_20C_upregulated
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065096:npr-8(ok1439)_downregulated_Day1_25C
WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
WBPaper00065749:endu-2(tm4977)_upregulated
WBPaper00065749:Heat-Shock_downregulated_N2
WBPaper00065835:Day5_vs_Day1_downregulated
WBPaper00065835:Day11_vs_Day1_upregulated
WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day5
WBPaper00065841:1_0
WBPaper00065841:12_0
WBPaper00065841:44_1
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065984:pals-17(syb3980)_upregulated
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066005:RAGA-1_degradation_somatic_upregulated
WBPaper00066093:E.coli-purE_downregulated
WBPaper00066110:Cisplatin_downregulated_diploid
WBPaper00066110:Doxorubicin_downregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_downregulated
WBPaper00066232:hsf-1(RNAi)_downregulated_WT
cgc4386_cluster_6_2
cgc4489_group_21
WBPaper00013489:Ray_Enriched
WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
WBPaper00025032:cluster_63
WBPaper00025032:cluster_168
WBPaper00025141:N2_Expressed_Genes
WBPaper00027111:rde-3(ne298)_upregulated
WBPaper00027111:rrf-2(ok210)_upregulated
WBPaper00029437:dcr-1_upregulated
WBPaper00029437:rde-4_downregulated
WBPaper00030985:Serratia_marcesens_downregulated
WBPaper00031832:slr-2_regulated
WBPaper00033101:spr-5_regulated
WBPaper00035227:heat_shock_regulated
WBPaper00035479:daf-16(RNAi)_downregulated
WBPaper00035873:osm-7_regulated
WBPaper00035873:osm-11_regulated
WBPaper00036123:Cadmium_regulated
WBPaper00036123:Fluoranthene_regulated
WBPaper00036383:ash-2_Day8_regulated
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_aging
WBPaper00040858:eQTL_regulated_developing
WBPaper00040858:eQTL_regulated_old
WBPaper00040858:eQTL_regulated_reproductive
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00041002:HF_3d_2.0mM_Up
WBPaper00041609:hpl-1_hpl-2_upregulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00041960:daf-16_fasting_upregulated
WBPaper00041960:kgb-1_fasting_upregulated
WBPaper00041960:N2_fasting_upregulated
WBPaper00041960:N2_fasting_upregulated_9hto12h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00042258:DA1877_downregulated_GravidAdult
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00046639:tyrosol_upregulated
WBPaper00047070:N2_starvation_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00048989:N2_allantoin_upregulated
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00050767:Octopamine_induced
WBPaper00056330:mrps-5(RNAi)_downregulated
[cgc5767]:cluster_5
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(122_min)
[cgc5767]:expression_class_SE
[cgc5767]:expression_class_SE_pi(122_min)
[cgc6390]:Cluster_A
InteractionWBInteraction000181597
WBInteraction000192583
WBInteraction000196649
WBInteraction000196776
WBInteraction000197271
WBInteraction000200127
WBInteraction000201836
WBInteraction000210913
WBInteraction000218268
WBInteraction000218604
WBInteraction000219078
WBInteraction000219440
WBInteraction000223480
WBInteraction000234932
WBInteraction000244854
WBInteraction000250643
WBInteraction000253252
WBInteraction000254260
WBInteraction000254513
WBInteraction000256415
WBInteraction000256590
WBInteraction000257311
WBInteraction000259914
WBInteraction000263368
WBInteraction000263792
WBInteraction000266316
WBInteraction000268159
WBInteraction000268202
WBInteraction000268371
WBInteraction000269314
WBInteraction000270992
WBInteraction000271485
WBInteraction000271839
WBInteraction000276118
WBInteraction000276405
WBInteraction000279088
WBInteraction000279202
WBInteraction000280391
WBInteraction000284361
WBInteraction000284473
WBInteraction000284846
WBInteraction000286428
WBInteraction000287456
WBInteraction000289246
WBInteraction000289631
WBInteraction000293851
WBInteraction000294150
WBInteraction000295413
WBInteraction000297795
WBInteraction000298521
WBInteraction000299089
WBInteraction000299147
WBInteraction000299326
WBInteraction000303512
WBInteraction000305181
WBInteraction000310964
WBInteraction000311635
WBInteraction000316249
WBInteraction000316790
WBInteraction000318488
WBInteraction000318613
WBInteraction000319094
WBInteraction000319617
WBInteraction000320309
WBInteraction000321244
WBInteraction000323881
WBInteraction000323960
WBInteraction000324341
WBInteraction000328155
WBInteraction000329351
WBInteraction000335072
WBInteraction000336496
WBInteraction000336889
WBInteraction000336980
WBInteraction000337073
WBInteraction000337827
WBInteraction000338334
WBInteraction000338680
WBInteraction000340085
WBInteraction000342252
WBInteraction000343587
WBInteraction000345138
WBInteraction000346501
WBInteraction000347106
WBInteraction000348893
WBInteraction000349842
WBInteraction000350818
WBInteraction000352103
WBInteraction000353141
WBInteraction000354201
WBInteraction000355052
WBInteraction000360243
WBInteraction000362473
WBInteraction000364313
WBInteraction000364823
WBInteraction000364896
WBInteraction000365865
WBInteraction000366513
WBInteraction000366915
WBInteraction000367499
WBInteraction000373461
WBInteraction000374156
WBInteraction000375759
WBInteraction000376111
WBInteraction000377322
WBInteraction000378264
WBInteraction000378624
WBInteraction000379405
WBInteraction000380364
WBInteraction000380392
WBInteraction000381944
WBInteraction000385345
WBInteraction000386005
WBInteraction000386006
WBInteraction000388739
WBInteraction000389550
WBInteraction000389829
WBInteraction000389835
WBInteraction000390135
WBInteraction000390196
WBInteraction000392233
WBInteraction000397577
WBInteraction000398394
WBInteraction000399745
WBInteraction000399766
WBInteraction000400518
WBInteraction000400680
WBInteraction000402969
WBInteraction000406449
WBInteraction000406675
WBInteraction000409815
WBInteraction000411747
WBInteraction000412427
WBInteraction000413277
WBInteraction000415905
WBInteraction000416249
WBInteraction000417641
WBInteraction000418600
WBInteraction000418859
WBInteraction000420492
WBInteraction000421084
WBInteraction000423726
WBInteraction000423727
WBInteraction000425878
WBInteraction000427369
WBInteraction000429640
WBInteraction000432436
WBInteraction000433844
WBInteraction000434269
WBInteraction000436765
WBInteraction000437783
WBInteraction000439490
WBInteraction000439599
WBInteraction000440464
WBInteraction000440937
WBInteraction000441671
WBInteraction000444972
WBInteraction000445256
WBInteraction000446055
WBInteraction000449654
WBInteraction000450420
WBInteraction000450813
WBInteraction000453726
WBInteraction000454258
WBInteraction000455937
WBInteraction000456690
WBInteraction000457081
WBInteraction000457090
WBInteraction000459422
WBInteraction000464771
WBInteraction000464772
WBInteraction000464773
WBInteraction000472365
WBInteraction000472487
WBInteraction000523809
WBInteraction000525971
WBInteraction000525972
WBInteraction000525973
WBInteraction000533436
WBInteraction000547878
WBInteraction000550860
WBInteraction000570340
Map_infoMapIIIPosition-1.1954Error0.002656
PositivePositive_cloneF23F12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00028945
WBPaper00058798
WBPaper00061738
WBPaper00061938
WBPaper00062117
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene