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WormBase Tree Display for Gene: WBGene00019327

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Name Class

WBGene00019327SMapS_parentSequenceK02F3
IdentityVersion2
NameCGC_namezip-2Person_evidenceWBPerson1997
WBPerson460
Sequence_nameK02F3.4
Molecular_nameK02F3.4
K02F3.4.1
CE23848
K02F3.4.2
K02F3.4.3
Other_nameCELE_K02F3.4Accession_evidenceNDBBX284603
Public_namezip-2
DB_infoDatabaseAceViewgene3B453
WormQTLgeneWBGene00019327
WormFluxgeneWBGene00019327
NDBlocus_tagCELE_K02F3.4
PanthergeneCAEEL|WormBase=WBGene00019327|UniProtKB=Q21148
familyPTHR23334
NCBIgene175240
RefSeqproteinNM_001384015.2
SwissProtUniProtAccQ21148
TREEFAMTREEFAM_IDTF317134
UniProt_GCRPUniProtAccQ21148
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:01WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
218 Jul 2005 13:34:00WBPerson2970Name_changeCGC_namezip-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classzip
Allele (51)
StrainWBStrain00037649
RNASeq_FPKM (74)
GO_annotation (25)
Ortholog (23)
ParalogWBGene00016754Caenorhabditis elegansFrom_analysisPanther
WBGene00016997Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00017755Caenorhabditis elegansFrom_analysisPanther
WBGene00021552Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionzip-2 encodes a bZIP transcription factor; ZIP-2 activity is required for regulating one branch of the immune response pathway that responds to infection by virulent strains of the bacterial pathogen Pseudomonas aeruginosa; specifically, ZIP-2 is required for inducing expression of a subset of infection response genes, including irg-1 and irg-2, and for full resistance to P. aeruginosa infection.Paper_evidenceWBPaper00027309
WBPaper00035891
Curator_confirmedWBPerson1843
Date_last_updated08 Feb 2010 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to bacterium and positive regulation of macromolecule biosynthetic process. Predicted to be located in nucleus. Expressed in pharynx.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Modifies_diseaseDOID:14330
Modifies_disease_in_annotationWBDOannot00000499
Molecular_infoCorresponding_CDSK02F3.4
Corresponding_transcriptK02F3.4.1
K02F3.4.2
K02F3.4.3
Other_sequence (25)
Associated_feature (16)
Gene_product_binds (249)
Transcription_factorWBTranscriptionFactor000223
Experimental_infoRNAi_result (25)
Expr_patternExpr7776
Expr10045
Expr1020648
Expr1038353
Expr1153467
Expr2018156
Expr2036293
Drives_constructWBCnstr00012921
WBCnstr00015019
WBCnstr00015163
WBCnstr00019915
WBCnstr00022575
WBCnstr00025914
Construct_productWBCnstr00016820
WBCnstr00018893
WBCnstr00018894
WBCnstr00019915
WBCnstr00022575
WBCnstr00025914
Regulate_expr_clusterWBPaper00035891:PA_induced_zip-2_dependent
WBPaper00035891:zip-2(RNAi)_downregulated
WBPaper00035891:zip-2(RNAi)_upregulated
WBPaper00053605:zip-2(RNAi)_downregulated
WBPaper00053605:zip-2(RNAi)_upregulated
Microarray_results (21)
Expression_cluster (221)
Interaction (49)
WBProcessWBbiopr:00000008
WBbiopr:00000039
Map_infoMapIIIPosition-25.7689
PositivePositive_cloneK02F3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (32)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
[200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-25.7711)
MethodGene