WormBase Tree Display for Gene: WBGene00019327

WBGene00019327 SMap: S_parent: Sequence: K02F3
  Identity: Version: 2
    Name: CGC_name: zip-2 Person_evidence: WBPerson1997
            WBPerson460
      Sequence_name: K02F3.4
      Molecular_name: K02F3.4
        K02F3.4.1
        CE23848
        K02F3.4.2
        K02F3.4.3
      Other_name: CELE_K02F3.4 Accession_evidence: NDB BX284603
      Public_name: zip-2
    DB_info: Database: AceView gene 3B453
        WormQTL gene WBGene00019327
        WormFlux gene WBGene00019327
        NDB locus_tag CELE_K02F3.4
        Panther gene CAEEL|WormBase=WBGene00019327|UniProtKB=Q21148
          family PTHR23334
        NCBI gene 175240
        RefSeq protein NM_001384015.2
        SwissProt UniProtAcc Q21148
        TREEFAM TREEFAM_ID TF317134
        UniProt_GCRP UniProtAcc Q21148
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 18 Jul 2005 13:34:00 WBPerson2970 Name_change: CGC_name: zip-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: zip
    Allele (51)
    Strain: WBStrain00037649
    RNASeq_FPKM (74)
    GO_annotation (25)
    Ortholog (23)
    Paralog: WBGene00016754 Caenorhabditis elegans From_analysis: Panther
      WBGene00016997 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00017755 Caenorhabditis elegans From_analysis: Panther
      WBGene00021552 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: zip-2 encodes a bZIP transcription factor; ZIP-2 activity is required for regulating one branch of the immune response pathway that responds to infection by virulent strains of the bacterial pathogen Pseudomonas aeruginosa; specifically, ZIP-2 is required for inducing expression of a subset of infection response genes, including irg-1 and irg-2, and for full resistance to P. aeruginosa infection. Paper_evidence: WBPaper00027309
            WBPaper00035891
          Curator_confirmed: WBPerson1843
          Date_last_updated: 08 Feb 2010 00:00:00
      Automated_description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to bacterium and positive regulation of macromolecule biosynthetic process. Predicted to be located in nucleus. Expressed in pharynx. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Modifies_disease: DOID:14330
  Modifies_disease_in_annotation: WBDOannot00000499
  Molecular_info: Corresponding_CDS: K02F3.4
    Corresponding_transcript: K02F3.4.1
      K02F3.4.2
      K02F3.4.3
    Other_sequence (25)
    Associated_feature (16)
    Gene_product_binds (249)
    Transcription_factor: WBTranscriptionFactor000223
  Experimental_info: RNAi_result (25)
    Expr_pattern: Expr7776
      Expr10045
      Expr1020648
      Expr1038353
      Expr1153467
      Expr2018156
      Expr2036293
    Drives_construct: WBCnstr00012921
      WBCnstr00015019
      WBCnstr00015163
      WBCnstr00019915
      WBCnstr00022575
      WBCnstr00025914
    Construct_product: WBCnstr00016820
      WBCnstr00018893
      WBCnstr00018894
      WBCnstr00019915
      WBCnstr00022575
      WBCnstr00025914
    Regulate_expr_cluster: WBPaper00035891:PA_induced_zip-2_dependent
      WBPaper00035891:zip-2(RNAi)_downregulated
      WBPaper00035891:zip-2(RNAi)_upregulated
      WBPaper00053605:zip-2(RNAi)_downregulated
      WBPaper00053605:zip-2(RNAi)_upregulated
    Microarray_results (21)
    Expression_cluster (221)
    Interaction: WBInteraction000184857
      WBInteraction000376887
      WBInteraction000416848
      WBInteraction000425841
      WBInteraction000437262
      WBInteraction000452199
      WBInteraction000457966
      WBInteraction000462578
      WBInteraction000504268
      WBInteraction000505401
      WBInteraction000518582
      WBInteraction000523812
      WBInteraction000523813
      WBInteraction000523814
      WBInteraction000523815
      WBInteraction000523826
      WBInteraction000524506
      WBInteraction000525561
      WBInteraction000526172
      WBInteraction000527002
      WBInteraction000527776
      WBInteraction000527829
      WBInteraction000527830
      WBInteraction000527831
      WBInteraction000527832
      WBInteraction000527833
      WBInteraction000527834
      WBInteraction000527835
      WBInteraction000534518
      WBInteraction000536145
      WBInteraction000536155
      WBInteraction000536156
      WBInteraction000536159
      WBInteraction000536160
      WBInteraction000536161
      WBInteraction000537372
      WBInteraction000537373
      WBInteraction000537379
      WBInteraction000537396
      WBInteraction000537397
      WBInteraction000537398
      WBInteraction000537408
      WBInteraction000537409
      WBInteraction000537424
      WBInteraction000549852
      WBInteraction000549864
      WBInteraction000549865
      WBInteraction000549875
      WBInteraction000549878
    WBProcess: WBbiopr:00000008
      WBbiopr:00000039
  Map_info: Map: III Position: -25.7689
    Positive: Positive_clone: K02F3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (32)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-25.7711)
  Method: Gene