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WormBase Tree Display for Gene: WBGene00016419

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Name Class

WBGene00016419SMapS_parentSequenceC34G6
IdentityVersion2
NameCGC_nametyr-4Person_evidenceWBPerson69
Sequence_nameC34G6.2
Molecular_nameC34G6.2
C34G6.2.1
CE08574
Other_nameCELE_C34G6.2Accession_evidenceNDBBX284601
Public_nametyr-4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:57WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
211 Feb 2005 11:34:52WBPerson2970Name_changeCGC_nametyr-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtyr
Allele (44)
StrainWBStrain00031924
RNASeq_FPKM (74)
GO_annotation00024775
00122059
Ortholog (46)
ParalogWBGene00009001Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00010060Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010661Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00015332Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00021553Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00022231Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00017483Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionAutomated_descriptionPredicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human DCT (dopachrome tautomerase); TYR (tyrosinase); and TYRP1 (tyrosinase related protein 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050633Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:8465Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0070097Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12450)
DOID:8923Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0050632Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442,HGNC:12450,HGNC:2709)
DOID:12306Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0070095Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0070094Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:1909Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:10123Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442,HGNC:12450)
Molecular_infoCorresponding_CDSC34G6.2
Corresponding_transcriptC34G6.2.1
Other_sequence (47)
Associated_featureWBsf656345
WBsf217724
WBsf217725
WBsf217726
Experimental_infoRNAi_resultWBRNAi00098215Inferred_automaticallyRNAi_primary
WBRNAi00029552Inferred_automaticallyRNAi_primary
WBRNAi00003081Inferred_automaticallyRNAi_primary
WBRNAi00098219Inferred_automaticallyRNAi_primary
WBRNAi00001841Inferred_automaticallyRNAi_primary
WBRNAi00041928Inferred_automaticallyRNAi_primary
Expr_patternExpr1010270
Expr1037037
Expr1145935
Expr2017688
Expr2035826
Drives_constructWBCnstr00028083
Construct_productWBCnstr00028083
Microarray_results (19)
Expression_clusterWBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032031:DConiospora_downregulated_cDNA_12h
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00035269:cde-1_regulated
WBPaper00037047:insoluble_protein
WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00040990:PA14_downregulated
WBPaper00044426:rotenone_5day_downregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044578:reduced-humidity_downregulated_microarray
WBPaper00044656:tatn-1(qd182)_upregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_upregulated
WBPaper00045774:clk-1_upregulated
WBPaper00046012:tdp-1(ok803)_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
WBPaper00047131:daf-2(e1370)_upregulated_N2-background
WBPaper00047132:glp-1(ts)-25C_upregulated
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050080:rbr-2(tm3141)_downregulated
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050801:DAF-12_dauer_regulome
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050801:DPY-21_dauer_regulome
WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:body-muscle_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_specific
WBPaper00051265:F4_hrde-1(tm1200)_upregulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053302:zidovudine_24h_regulated
WBPaper00053318:mir-71(n4115)_upregulated_mRNA
WBPaper00053388:dauer_regulated_Cluster1
WBPaper00053402:cco-1(RNAi)_upregulated
WBPaper00053615:SMO-1_target
WBPaper00053771:up_at_dpy-7(e88)
WBPaper00053810:clk-1(qm30)_upregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00053810:isp-1(qm150)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00053814:15C_downregulated_PY79
WBPaper00055013:hmg-3(bar24)_upregulated
WBPaper00055013:spt-16(RNAi)_upregulated
WBPaper00055060:flr-1(RNAi)_downregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Psora_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rapamycin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin-Psora_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
WBPaper00056169:rrf-3(pk1426)_upregulated_L3
WBPaper00056284:ints-6(t1903)_upregulated
WBPaper00056443:DietaryRestriction_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057006:DietaryRestriction_downregulated
WBPaper00057041:spc-1(cas971)_upregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057288:Cold_downregulated_protein
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058711:wdr-5(ok1417)_upregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058725:sftb-1(cer39)_downregulated
WBPaper00058948:npr-8(ok1439)_downregulated_OP50
WBPaper00058969:RIS_depleted
WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
WBPaper00059537:ngn-1(ok2200)_upregulated
WBPaper00059566:wdr-23(mac32)_upregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059816:crh-1(n3315)_downrgulated
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00059895:wounding_upregulated
WBPaper00059987:Wounding_upregulated
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060661:sensory-neuron_depleted
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060703:nas-38(ok3407)_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060871:M.humicola-infection_24h_regulated
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00060921:cat-2(e1112)_downregulated
WBPaper00061045:Y56A3A.22(cck200)_upregulated
WBPaper00061340:T
WBPaper00061341:28C_24h_upregulated
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061527:ttr-18-C54D10.3
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062347:blmp-1(tm548)_upregulated
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00062715:blmp-1(s71)_upregulated
WBPaper00064005:starvation_downregulated_N2_mRNA
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064130:Beta-Amyloid_downregulated_protein
WBPaper00064539:nhr-114(gk849)_upregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064727:daf-2(e1370)_upregulated
WBPaper00064769:him-17(me24)_upregulated
WBPaper00065096:npr-8(ok1439)_upregulated_Day1_20C
WBPaper00065120:body-muscle-transcriptome
WBPaper00065373:Cisplatin_upregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065373:sek-1(km4)_downregulated_Ref
WBPaper00065392:Lb.plantarum_downregulated
WBPaper00065392:Lb.rhamnosus_downregulated
WBPaper00065835:Day11_vs_Day1_downregulated
WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
WBPaper00065835:mtH2S-AP39-L1-treatment_upregulated_Day11
WBPaper00065841:2_0
WBPaper00065841:33_0
WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
WBPaper00066232:ash-2(RNAi)_downregulated_WT
cgc4489_group_14
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026980:intestine_enriched
WBPaper00029437:dcr-1_upregulated
WBPaper00031532:Larva_Pan_Neuronal_Depleted
WBPaper00032062:age_regulated_genes
WBPaper00032948:FedUp
WBPaper00034661:AgNPs_downregulated
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00035873:osm-8_regulated
WBPaper00035873:osm-11_regulated
WBPaper00036123:Cadmium_regulated
WBPaper00036286:Pattern_D
WBPaper00036383:ash-2_Day8_regulated
WBPaper00038172:crh-1null_up_regulated
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
WBPaper00040210:Chlorpyrifos_24C_regulated
WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
WBPaper00040823:alg-1(gk214)_upregulated
WBPaper00041002:HF_11d_2.0mM_Up
WBPaper00041207:CE_dauer_down
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00042128:gei-8(ok1671)_upregulated
WBPaper00042258:DA1877_upregulated_GravidAdult
WBPaper00044091:Bpseudomallei_induced_8h
WBPaper00047070:N2_UV_upregulated
WBPaper00047070:xpa-1_UV_upregulated
WBPaper00048989:N2_allantoin_downregulated
WBPaper00050520:lagr-1(gk327);hyl-1(ok976)_upregulated
WBPaper00053236:Starvation_regulated_N2
WBPaper00057098:SiO2-nanoparticles_downregulated
Interaction (25)
Map_infoMapIPosition0.475289Error0.001229
PositivePositive_cloneC34G6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5068
4575
4601
Pseudo_map_position
ReferenceWBPaper00044177
WBPaper00055090
WBPaper00061547
WBPaper00065140
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene