WormBase Tree Display for Gene: WBGene00022231
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| WBGene00022231 | SMap | S_parent | Sequence | Y73B6BL | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | tyr-6 | Person_evidence | WBPerson260 | |||||
| Sequence_name | Y73B6BL.1 | ||||||||
| Molecular_name | Y73B6BL.1 | ||||||||
| Y73B6BL.1.1 | |||||||||
| CE37586 | |||||||||
| Other_name | CELE_Y73B6BL.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | tyr-6 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:05 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 28 Jan 2010 16:20:10 | WBPerson2970 | Name_change | CGC_name | tyr-6 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tyr | ||||||||
| Allele (65) | |||||||||
| Strain | WBStrain00036861 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00088884 | ||||||||
| 00126383 | |||||||||
| Ortholog (40) | |||||||||
| Paralog | WBGene00009001 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00010060 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00010661 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00015332 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00016419 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00017483 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00021553 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | tyr-6 is orthologous to the human gene tyrosinase (TYR), which is involved in the conversion of tyrosine to melanin. | Curator_confirmed | WBPerson324 | |||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 21 May 2013 00:00:00 | ||||||||
| Automated_description | Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in oculocutaneous albinism type III and pigmentation disease. Is an ortholog of human DCT (dopachrome tautomerase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070097 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12450) | ||||
| DOID:10123 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12450) | ||||||
| DOID:0050632 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12450,HGNC:2709) | ||||||
| Disease_relevance | Mutations in human tyrosinase (TYR), which is involved in the conversion of tyrosine to melanine, are implicated in skin pigmentation disorders, melanoma and albinism. | Homo sapiens | Accession_evidence | OMIM | 203100 | ||||
| 606952 | |||||||||
| 103470 | |||||||||
| 601800 | |||||||||
| 606933 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 28 May 2013 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y73B6BL.1 | |||||||
| Corresponding_CDS_history | Y73B6BL.1:wp98 | ||||||||
| Y73B6BL.1:wp131 | |||||||||
| Corresponding_transcript | Y73B6BL.1.1 | ||||||||
| Other_sequence (19) | |||||||||
| Associated_feature | WBsf718107 | ||||||||
| WBsf996754 | |||||||||
| WBsf996755 | |||||||||
| WBsf996756 | |||||||||
| WBsf1017528 | |||||||||
| WBsf1017529 | |||||||||
| WBsf1017530 | |||||||||
| WBsf228416 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00058309 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00000744 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1011954 | ||||||||
| Expr1161718 | |||||||||
| Expr2017690 | |||||||||
| Expr2035828 | |||||||||
| Drives_construct | WBCnstr00024328 | ||||||||
| Construct_product | WBCnstr00024328 | ||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (113) | |||||||||
| Map_info | Map | IV | Position | 3.20057 | Error | 0.000208 | |||
| Positive | Positive_clone | Y73B6BL | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00065140 | ||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
