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WormBase Tree Display for Gene: WBGene00003090

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Name Class

WBGene00003090SMapS_parentSequenceY22F5A
IdentityVersion1
NameCGC_namelys-1Person_evidenceWBPerson168
Sequence_nameY22F5A.4
Molecular_nameY22F5A.4
Y22F5A.4.1
CE16605
Other_nameCELE_Y22F5A.4Accession_evidenceNDBBX284605
Public_namelys-1
DB_infoDatabaseAceViewgene5K759
WormQTLgeneWBGene00003090
WormFluxgeneWBGene00003090
NDBlocus_tagCELE_Y22F5A.4
PanthergeneCAEEL|WormBase=WBGene00003090|UniProtKB=O62415
familyPTHR23208
NCBIgene179428
RefSeqproteinNM_073241.7
SwissProtUniProtAccO62415
TREEFAMTREEFAM_IDTF316378
UniProt_GCRPUniProtAccO62415
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:30WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlys
Allele (22)
StrainWBStrain00032578
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (33)
ParalogWBGene00003091Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00003096Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00003097Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00003092Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003098Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003093Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003099Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003094Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003095Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionlys-1 encodes a putative lysozyme, whose overexpression increasesresistance to infection by Serratia marcescens; lys-1(RNAi) animals havenormal resistance to S. marcescens, perhaps because of geneticredundancy with the LYS-1 paralogs LYS-2 to -8 and LYS-10; in uninfectedanimals, LYS-1 is expressed in the intestine and in IL1/IL2 neurons,along with a few unidentified head neurons; in intestinal cells, LYS-1localizes to apical vesicles; LYS-1 expression is induced by infectionby Pseudomonas aeruginosa but not S. marcescens; LYS-1 expression ispromoted by DBL-1, TIR-1 and NSY-1, and perhaps also by ELT-2, but notby DAF-16; LYS-1 and its paralogs are more similar to lysozymes from theamoeboid protozoon Entamoeba histolytica than to more familiar ones fromvertebrates.Paper_evidenceWBPaper00005382
WBPaper00028482
WBPaper00029438
Curator_confirmedWBPerson567
Date_last_updated31 May 2007 00:00:00
Automated_descriptionInvolved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and innate immune response. Located in apical part of cell and cytoplasmic vesicle. Expressed in intestine and neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY22F5A.4
Corresponding_transcriptY22F5A.4.1
Other_sequence (57)
Associated_featureWBsf647149
WBsf661620
WBsf661621
WBsf1001086
WBsf1001087
WBsf1020290
WBsf1020291
WBsf232353
WBsf232354
WBsf232355
Gene_product_bindsWBsf978958
WBsf978961
Experimental_info (8)
Map_infoMapVPosition2.4495Error0.001114
PositivePositive_cloneY22F5AInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005382
WBPaper00005569
WBPaper00005668
WBPaper00006302
WBPaper00006437
WBPaper00011496
WBPaper00024209
WBPaper00025180
WBPaper00027295
WBPaper00028482
WBPaper00029438
WBPaper00031802
WBPaper00034325
WBPaper00034591
WBPaper00036878
WBPaper00037983
WBPaper00039111
WBPaper00040135
WBPaper00040853
WBPaper00041533
WBPaper00044217
WBPaper00046621
WBPaper00047109
WBPaper00051227
WBPaper00059839
WBPaper00060200
WBPaper00061319
WBPaper00061383
WBPaper00062392
WBPaper00065026
WBPaper00065034
WBPaper00065331
WBPaper00065718
WBPaper00065850
WBPaper00065852
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene