WormBase Tree Display for Gene: WBGene00003096
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WBGene00003096 | SMap | S_parent | Sequence | C02A12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | lys-7 | Person_evidence | WBPerson168 | |||||
Sequence_name | C02A12.4 | ||||||||
Molecular_name | C02A12.4 | ||||||||
C02A12.4.1 | |||||||||
CE07828 | |||||||||
Other_name | CELE_C02A12.4 | Accession_evidence | NDB | BX284605 | |||||
Public_name | lys-7 | ||||||||
DB_info | Database | AceView | gene | 5D960 | |||||
WormQTL | gene | WBGene00003096 | |||||||
WormFlux | gene | WBGene00003096 | |||||||
NDB | locus_tag | CELE_C02A12.4 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00003096|UniProtKB=O16202 | |||||||
family | PTHR23208 | ||||||||
NCBI | gene | 178772 | |||||||
RefSeq | protein | NM_071571.9 | |||||||
SwissProt | UniProtAcc | O16202 | |||||||
TREEFAM | TREEFAM_ID | TF316378 | |||||||
UniProt_GCRP | UniProtAcc | O16202 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | lys | ||||||||
Allele (30) | |||||||||
Strain | WBStrain00031984 | ||||||||
WBStrain00031985 | |||||||||
WBStrain00004711 | |||||||||
WBStrain00004740 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Ortholog (37) | |||||||||
Paralog | WBGene00003090 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00003091 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00003092 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00003093 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00003094 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00003095 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00003097 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00003098 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00003099 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | lys-7 encodes an enzyme homologous to an antimicrobial lysozyme encoded by the LYS4 gene of the protozoan parasite Entamoeba histolytica; LYS-7 functions in the innate immune response as an antimicrobial enzyme that, by homology, hydrolyzes the 1,4-beta-linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid in peptidoglycan heteropolymers of prokaryotic cell walls; loss of lys-7 activity results in enhanced susceptibility to P. aeruginosa PA14, renders worms susceptible to Cryptococcus neoformans killing, but enhances tolerance to the enteric bacteria Salmonella typhimurium; lys-7 expression is significantly upregulated in response to infection with the Gram-negative bacterium Serratia marcescens; constitutive expression of lys-7 mRNA is detected in the intestine and the intestinal valve cells. | Paper_evidence | WBPaper00004651 | |||||
WBPaper00005382 | |||||||||
WBPaper00005569 | |||||||||
WBPaper00005654 | |||||||||
WBPaper00041211 | |||||||||
WBPaper00038223 | |||||||||
WBPaper00032276 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 19 Feb 2014 00:00:00 | ||||||||
Automated_description | Involved in defense response to other organism. Expressed in head neurons; intestine; and rectal gland cell. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS290 version of WormBase | ||||||||
Date_last_updated | 11 Sep 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C02A12.4 | |||||||
Corresponding_transcript | C02A12.4.1 | ||||||||
Other_sequence (84) | |||||||||
Associated_feature | WBsf019148 | ||||||||
WBsf019149 | |||||||||
WBsf652532 | |||||||||
WBsf233493 | |||||||||
WBsf233494 | |||||||||
Experimental_info | RNAi_result (21) | ||||||||
Expr_pattern | Expr1973 | ||||||||
Expr4716 | |||||||||
Expr10716 | |||||||||
Expr1018008 | |||||||||
Expr1143497 | |||||||||
Expr2013318 | |||||||||
Expr2031549 | |||||||||
Drives_construct | WBCnstr00009965 | ||||||||
WBCnstr00012193 | |||||||||
WBCnstr00015892 | |||||||||
WBCnstr00017492 | |||||||||
WBCnstr00036232 | |||||||||
WBCnstr00041439 | |||||||||
Construct_product | WBCnstr00009965 | ||||||||
WBCnstr00012193 | |||||||||
WBCnstr00036232 | |||||||||
Microarray_results (18) | |||||||||
Expression_cluster (404) | |||||||||
Interaction (200) | |||||||||
WBProcess | WBbiopr:00000008 | ||||||||
WBbiopr:00000039 | |||||||||
Map_info | Map | V | Position | -10.8998 | Error | 0.024633 | |||
Positive | Positive_clone | C02A12 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4881 | |||||||
4924 | |||||||||
5423 | |||||||||
Pos_neg_data | 10776 | ||||||||
Pseudo_map_position | |||||||||
Reference (63) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |