Enriched in several structures, including hypodermis; neurons; pharyngeal muscle cell; rectal epithelial cell; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; quantitative PCR; tiling array; proteomic; and RNA-seq studies. Is affected by thirty-three chemicals including hydrogen sulfide; 1-methylnicotinamide; and nicotinic acid based on microarray; RNA-seq; and proteomic studies.