lir-2 encodes a LIN-26-like zinc-finger protein that shares a unique C2H2 motif together with LIR-1, LIR-3, and LIN-26; lir-2 is the upstream gene in an operon with lir-1 which is, in turn, the upstream gene in a second, overlapping operon with lin-26; lir-2 transcripts are ubiquitous in early embryos (2-200-cell stages).
Enriched in intestine; neurons; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including dpy-10; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; stavudine; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.