WormBase Tree Display for Gene: WBGene00001185
expand all nodes | collapse all nodes | view schema
| WBGene00001185 | SMap | S_parent | Sequence | F38G1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | egl-17 | Person_evidence | WBPerson268 | |||||
| Sequence_name | F38G1.2 | ||||||||
| Molecular_name | F38G1.2 | ||||||||
| F38G1.2.1 | |||||||||
| CE26435 | |||||||||
| F38G1.2.2 | |||||||||
| Other_name | CELE_F38G1.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | egl-17 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | egl | ||||||||
| Reference_allele | WBVar00143911 | ||||||||
| Allele (56) | |||||||||
| Legacy_information | e1313 : moderate to severe bloating 30% form bag-of-worms. Type A. ES3 (adult). NA1. | ||||||||
| See also e1313 | |||||||||
| [C.elegansII] e1313 : moderate to severe bloating, 30% form bag-of-worms. insensitive to serotonin and imipramine. Severe posterior displacement of hermaphrodite sex muscles (due to gonadal repulsion); enhancer of weak Tra mutation. Suppressed by clr-1 mutations.ES3 (adult), ME3. OA9: ay6, n1377, ay10 (putative null); all similar. Cloned: cosmid rescue. ay6, n1377 are deletions. [Stern and Horvitz 1991; Clark et al. 1993; MT; NH] | |||||||||
| Strain (28) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (32) | |||||||||
| Paralog | WBGene00002881 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | egl-17 encodes a fibroblast growth factor (FGF)-like protein; egl-17 activity is required for proper migration of the sex myoblasts, the cells that give rise to the egg-laying muscles, from the posterior region of the mid-body to a more central position in the animal, flanking the center of the gonad; egl-17 is expressed in the primary and secondary vulval cell lineages and in cells in the male tail. | Paper_evidence | WBPaper00002741 | |||||
| WBPaper00003045 | |||||||||
| WBPaper00003579 | |||||||||
| WBPaper00004362 | |||||||||
| WBPaper00006348 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 31 Aug 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in regulation of cell migration and regulation of egg-laying behavior. Located in extracellular space. Expressed in several structures, including M4 neuron; P5.p; P7.p; male-specific anatomical entity; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including germ cell cancer (multiple); hypogonadotropic hypogonadism (multiple); and prostate disease (multiple). Is an ortholog of human FGF18 (fibroblast growth factor 18) and FGF8 (fibroblast growth factor 8). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0090082 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3673) | ||||
| DOID:3594 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3686) | ||||||
| DOID:0090086 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3686) | ||||||
| DOID:3308 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3686) | ||||||
| DOID:1911 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3686) | ||||||
| DOID:8634 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3686) | ||||||
| DOID:11132 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3686) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3686) | ||||||
| Molecular_info | Corresponding_CDS | F38G1.2 | |||||||
| Corresponding_transcript | F38G1.2.1 | ||||||||
| F38G1.2.2 | |||||||||
| Other_sequence | Dviv_isotig16783 | ||||||||
| Associated_feature | WBsf019100 | ||||||||
| WBsf019101 | |||||||||
| WBsf919540 | |||||||||
| WBsf919541 | |||||||||
| WBsf919542 | |||||||||
| WBsf919543 | |||||||||
| WBsf1003792 | |||||||||
| WBsf1022133 | |||||||||
| WBsf1022134 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00089856 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00089986 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090145 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027850 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00046734 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090304 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (22) | |||||||||
| Drives_construct (66) | |||||||||
| Construct_product | WBCnstr00001841 | ||||||||
| WBCnstr00007859 | |||||||||
| WBCnstr00007861 | |||||||||
| WBCnstr00018735 | |||||||||
| WBCnstr00018736 | |||||||||
| WBCnstr00037043 | |||||||||
| WBCnstr00042075 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (66) | |||||||||
| Interaction (153) | |||||||||
| WBProcess | WBbiopr:00000020 | ||||||||
| WBbiopr:00000023 | |||||||||
| WBbiopr:00000070 | |||||||||
| WBbiopr:00000115 | |||||||||
| Map_info | Map | X | Position | -19.7025 | Error | 0.016129 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | meDf3 | |||||||
| meDf5 | |||||||||
| meDf2 | |||||||||
| meDf6 | |||||||||
| Positive_clone | F38G1 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| T28F1 | |||||||||
| Mapping_data | 2_point | 4453 | |||||||
| 6176 | |||||||||
| Multi_point (18) | |||||||||
| Landmark_gene | |||||||||
| Reference (144) | |||||||||
| Method | Gene |
