WormBase Tree Display for Gene: WBGene00001770

WBGene00001770 Evidence: Person_evidence: WBPerson1846
  SMap: S_parent: Sequence: F21H7
  Identity: Version: 1
    Name: CGC_name: gst-22
      Sequence_name: F21H7.1
      Molecular_name: F21H7.1
        F21H7.1.1
        CE15874
      Other_name: CELE_F21H7.1 Accession_evidence: NDB BX284605
      Public_name: gst-22
    DB_info: Database: AceView gene 5Q712
        WormQTL gene WBGene00001770
        WormFlux gene WBGene00001770
        NDB locus_tag CELE_F21H7.1
        Panther gene CAEEL|WormBase=WBGene00001770|UniProtKB=O45387
          family PTHR11571
        NCBI gene 180088
        RefSeq protein NM_074694.7
        TREEFAM TREEFAM_ID TF353041
        TrEMBL UniProtAcc O45387
        UniProt_GCRP UniProtAcc O45387
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gst
    Allele (73)
    RNASeq_FPKM (74)
    GO_annotation: 00034398
    Ortholog: WBGene00039594 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00156748 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00080210 Caenorhabditis remanei From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00091842 Pristionchus pacificus From_analysis: OMA
      WBGene00190016 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00133250 Caenorhabditis japonica From_analysis: TreeFam
            WormBase-Compara
      WBGene00090695 Pristionchus pacificus From_analysis: OMA
      WBGene00111073 Pristionchus pacificus From_analysis: OMA
      CBOVI.g9376 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP26.g10538 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g16864 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g17219 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP40.g5061 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      CSP40.g5062 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_01444.g16423 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_II.g6586 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp5_scaffold_00184.g6536 Caenorhabditis sinica From_analysis: WormBase-Compara
      GCK72_005853 Caenorhabditis remanei From_analysis: WormBase-Compara
      chrV_pilon.g17088 Caenorhabditis elegans From_analysis: WormBase-Compara
      FB:FBgn0010226 Drosophila melanogaster From_analysis: OrthoFinder
            OrthoInspector
            PhylomeDB
      ZFIN:ZDB-GENE-040426-2720 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-070822-30 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      MGI:1095417 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
      MGI:95863 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
      MGI:95856 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
      MGI:1309515 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
      MGI:3826440 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
      MGI:3704339 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
    Paralog (45)
    Structured_description: Automated_description: Enriched in several structures, including cephalic sheath cell; head mesodermal cell; intestine; muscle cell; and rectal gland cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Heme; 1-methylnicotinamide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal; Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F21H7.1
    Corresponding_transcript: F21H7.1.1
    Other_sequence: Hbac_isotig06146
    Associated_feature: WBsf669792
      WBsf235126
  Experimental_info: RNAi_result: WBRNAi00045252 Inferred_automatically: RNAi_primary
      WBRNAi00031241 Inferred_automatically: RNAi_primary
      WBRNAi00069807 Inferred_automatically: RNAi_primary
      WBRNAi00013712 Inferred_automatically: RNAi_primary
      WBRNAi00115537 Inferred_automatically: RNAi_primary
      WBRNAi00069823 Inferred_automatically: RNAi_primary
      WBRNAi00115472 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1019127
      Expr1149181
      Expr2012306
      Expr2030542
    Drives_construct: WBCnstr00036701
    Construct_product: WBCnstr00036701
    Microarray_results (16)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036738:4uM_Heme_upregulated
      WBPaper00036738:500uM_Heme_upregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:intestine_CoreEnriched
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:intestine_larva_SelectivelyEnriched
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044260:nicotic-acid_downregulated
      WBPaper00044426:rotenone_5day_downregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00045050:csr-1(hypomorph)_upregulated
      WBPaper00045390:tunicamycin_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00047131:daf-2(e1370)_downregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048952:glucose_repressed
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049495:starvation-refeeding_regulated
      WBPaper00049498:npr-1(ur89)_regulated_5
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049635:dop-1(vs100)_upregulated
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050163:let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050504:hrp-2(RNAi)_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050903:mir-35-41(nDf50)_20C_upregulated
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00051305:vit-2(ac3)_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:OP50_vs_PY79_downregulated_PY79
      WBPaper00053909:N2_vs_CB4856_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056218:daf-16(mu86)_downregulated_Day7
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056619:CEPsh_enriched
      WBPaper00056826:hmc_biased
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00057196:raga-1(ok386)_upregulated)
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058958:10mGy-irradiation-72h_upregulated
      WBPaper00059253:sucrose_upregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059537:ngn-1(ok2200)_upregulated
      WBPaper00059605:mut-16(pk710)_downregulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060526:plp-1(ok2155)_downregulated
      WBPaper00060634:fhod-1(tm2363)_downregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060744:Radiation_downregulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:M.braciatum_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061340:BWM_anterior
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061527:F58F9.3_11574-R07B7.6
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061651:Rectal_gland_enriched
      WBPaper00061823:mex-3(spr9)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062446:nhr-8(ok186)_upregulated
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064762:freezing-thaw_regulated
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065749:Heat-Shock-With-Recovery_upregulated_N2
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-L1-treatment_downregulated_Day1
      WBPaper00065841:3_4
      WBPaper00065841:3_5
      WBPaper00065841:30_0
      WBPaper00065841:30_3
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4386_cluster_3_3
      cgc4489_group_14
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025099:NI_specific
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00027111:rde-3(r459)_upregulated
      WBPaper00028482:PA14_upregulated
      WBPaper00028789:PA14_vs_gacA_upregulated_4hr
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00028789:PA14_vs_OP50_upregulated_8hr
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031703:heme_responsive_5
      WBPaper00031850:mdt-15(RNAi)_upregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035560:ahr-1_downregulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035892:Y.pestis_regulated
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038231:Cry5B_2-fold_upregulated
      WBPaper00038304:octr-1_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040821:Au-NP_regulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040876:mir-35_upregulated
      WBPaper00040963:Q200_up
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041906:I-3690_I-4317_vs_OP50_3d
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00044013:nasp-1_downregulated
      WBPaper00044091:Bpseudomallei_induced_2h
      WBPaper00044091:Bpseudomallei_induced_4h
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048637:lin-35(n745)_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
    Interaction (21)
  Map_info: Map: V Position: 9.85471 Error: 0.001009
    Positive: Positive_clone: F21H7 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00028883
    WBPaper00032108
    WBPaper00036738
    WBPaper00038491
    WBPaper00055090
    WBPaper00060839
    WBPaper00062625
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene