WBGene00006761 | SMap | S_parent | Sequence | F57H12 |
| Identity | Version | 1 |
| | Name | CGC_name | unc-24 | Person_evidence | WBPerson261 |
| | | Sequence_name | F57H12.2 |
| | | Molecular_name | F57H12.2 |
| | | | F57H12.2.1 |
| | | | CE52881 |
| | | Other_name | CELE_F57H12.2 | Accession_evidence | NDB | BX284604 |
| | | Public_name | unc-24 |
| | DB_info | Database (9) |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:42 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | unc |
| | Reference_allele | WBVar00142989 |
| | Allele (40) |
| | Legacy_information | e138amber : weak kinker tends to back often forms omega shape fairly active healthy. ES3 ME1. NA4 (e448 e927 etc.). |
| | | See also e2124, e2386, e2409 |
| | | [C.elegansII] e138amb : weak kinker, tends to back, often forms omega shape; fairly active; healthy. Severe kinker in L1. Suppresses anaesthetic hypersensitivity of unc-79 and unc-80 mutants.ES3 ME1. OA>10: e448, e927pdi, e1172icr, e2386, q327 etc. Cloned: cosmid rescue (C56C3). [Riddle and Brenner 1978; Morgan et al. 1991; MQ] |
| | Strain (96) |
| | RNASeq_FPKM (74) |
| | GO_annotation | 00082434 |
| | | 00082435 |
| | | 00114764 |
| | | 00114765 |
| | Ortholog (36) |
| | Paralog | WBGene00003166 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006063 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006064 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006065 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006066 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006067 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006068 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006741 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006061 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | Structured_description | Concise_description | unc-24 encodes a protein that contains a stomatin-like domain and a lipid transfer domain; unc-24 activity is essential for normal locomotion and for wild-type sensitivity to lipid-soluble volatile anesthetics; unc-24 is genetically epistatic to unc-79 and to unc-1, which encodes an additional stomatin whose stability and localization to the nerve ring are dependent upon UNC-24; unc-24 is expressed in the touch receptor neurons as well as neurons in the ventral cord. | Paper_evidence | WBPaper00002474 |
| | | | | | WBPaper00004649 |
| | | | | | WBPaper00024406 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | | WBPerson567 |
| | | | | Date_last_updated | 28 Aug 2006 00:00:00 |
| | | Automated_description | Predicted to be located in plasma membrane. Is an ortholog of human STOML1 (stomatin like 1). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | F57H12.2 |
| | Corresponding_CDS_history | F57H12.2:wp268 |
| | Corresponding_transcript | F57H12.2.1 |
| | Other_sequence | JI171814.1 |
| | | Oden_isotig19746 |
| | | CJC06246_1 |
| | | Dviv_isotig24668 |
| | Associated_feature | WBsf646133 |
| | | WBsf997090 |
| | | WBsf997091 |
| | | WBsf228607 |
| Experimental_info | RNAi_result (12) |
| | Expr_pattern | Expr3115 |
| | | Expr1017962 |
| | | Expr1032834 |
| | | Expr1152652 |
| | | Expr2017857 |
| | | Expr2035993 |
| | Drives_construct | WBCnstr00011147 |
| | | WBCnstr00034166 |
| | Construct_product | WBCnstr00034166 |
| | Antibody | WBAntibody00000752 |
| | Microarray_results (20) |
| | Expression_cluster | WBPaper00033065:cyc-1(RNAi)_upregulated |
| | | WBPaper00035211:age-1_vs_N2_downregulated |
| | | WBPaper00037950:A-class-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:A-class-motor-neurons_larva_enriched |
| | | WBPaper00037950:all-neurons_L2-larva_expressed |
| | | WBPaper00037950:all-neurons_larva_enriched |
| | | WBPaper00037950:AVA-neuron_L1-larva_expressed |
| | | WBPaper00037950:AVE-neuron_L1-larva_expressed |
| | | WBPaper00037950:bodywall-muscle_L2-larva_expressed |
| | | WBPaper00037950:bodywall-muscle_larva_enriched |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray |
| | | WBPaper00040420:ALM_PLM_enriched |
| | | WBPaper00040420:FLP_enriched |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00045390:ubc-9(RNAi)_downregulated |
| | | WBPaper00045420:fertilization_upregulated_transcript |
| | | WBPaper00046805:csr-1(RNAi)_upregulated_Set1 |
| | | WBPaper00048923:Aging_regulated |
| | | WBPaper00048988:neuron_enriched |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053771:up_at_dpy-7(e88) |
| | | WBPaper00054758:alg-1(gk204)_upregulated |
| | | WBPaper00055103:thoc-5(wy822)_upregulated |
| | | WBPaper00055354:eat-2(ad1116)_upregulated |
| | | WBPaper00055354:Rapamycin-Metformin_upregulated |
| | | WBPaper00055354:Rapamycin_downregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_upregulated |
| | | WBPaper00055354:Rifampicin_upregulated |
| | | WBPaper00055565:AVK_enriched |
| | | WBPaper00056034:pals-22(jy3)_upregulated |
| | | WBPaper00056167:Cry5B_upregulated |
| | | WBPaper00056443:sek-1(km4)_upregulated |
| | | WBPaper00056826:hmc_biased |
| | | WBPaper00056855:his-72(uge40)_upregulated |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058691:set-2(bn129)_upregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00059027:neuron-synapses_depleted |
| | | WBPaper00059117:B.subtilis_downregulated |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00060014:set-2(zr2012)_downregulated |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061210:huIs179_upregulated |
| | | WBPaper00061340:AIB |
| | | WBPaper00061340:AIM |
| | | WBPaper00061340:ALA |
| | | WBPaper00061340:ALM_BDU |
| | | WBPaper00061340:ALM_PLM |
| | | WBPaper00061340:ALN |
| | | WBPaper00061340:AVA |
| | | WBPaper00061340:AVD |
| | | WBPaper00061340:DA |
| | | WBPaper00061340:DA_DB |
| | | WBPaper00061340:DB |
| | | WBPaper00061340:DD |
| | | WBPaper00061340:DVC |
| | | WBPaper00061340:FLP |
| | | WBPaper00061340:hmc |
| | | WBPaper00061340:hmc_homolog |
| | | WBPaper00061340:Intestinal_and_rectal_muscle |
| | | WBPaper00061340:mu_int_mu_anal |
| | | WBPaper00061340:mu_sph |
| | | WBPaper00061340:PLM |
| | | WBPaper00061340:PVR |
| | | WBPaper00061340:RIB |
| | | WBPaper00061340:RIC |
| | | WBPaper00061340:RID |
| | | WBPaper00061340:RIH |
| | | WBPaper00061340:SIA |
| | | WBPaper00061340:SIB |
| | | WBPaper00061340:SMB |
| | | WBPaper00061340:SMD |
| | | WBPaper00061341:28C_48h_upregulated |
| | | WBPaper00061479:hda-1(ne4752)_upregulated |
| | | WBPaper00061527:sol-1-jnk-1_18695 |
| | | WBPaper00061651:ALM_enriched |
| | | WBPaper00061651:AVM_enriched |
| | | WBPaper00061651:PLM_enriched |
| | | WBPaper00061651:PVD_enriched |
| | | WBPaper00061651:PVM_enriched |
| | | WBPaper00062103:neuron_enriched |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062325:muscle_enriched_coding-RNA |
| | | WBPaper00062440:crh-1(n3315)_downregulated |
| | | WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065158:AFD_enriched |
| | | WBPaper00065749:endu-2(tm4977)_upregulated |
| | | WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977) |
| | | WBPaper00065841:20_0 |
| | | WBPaper00065841:20_1 |
| | | WBPaper00065841:20_2 |
| | | WBPaper00065841:54_0 |
| | | WBPaper00065945:epidermis-rpoa-2(-)_upregulated_transcript |
| | | WBPaper00065945:global-rpoa-2(-)_upregulated_transcript |
| | | WBPaper00066062:xrep-4(lax137)_upregulated |
| | | cgc4489_group_17 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00030839:Larval_Pan_Neuronal |
| | | WBPaper00031003:hlh_1_enriched |
| | | WBPaper00031532:Larva_Pan_Neuronal_Enriched |
| | | WBPaper00034757:up_by_oxidative_stress |
| | | WBPaper00035588:alg-1(-)_upregulated |
| | | WBPaper00039866:ClassComp_daf-19_downregulated |
| | | WBPaper00040858:eQTL_regulated_juvenile |
| | | WBPaper00040876:mir-35_downregulated |
| | | WBPaper00041174:environmental |
| | | WBPaper00041174:environmental_prime |
| | | WBPaper00045673:colistin_upregulated |
| | | WBPaper00048637:lin-35(n745)_starvation_downregulated |
| | | WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo |
| | | WBPaper00057098:SiO2-nanoparticles_upregulated |
| | Interaction (68) |
| Map_info | Map | IV | Position | 3.51451 | Error | 0.003721 |
| | Well_ordered |
| | Positive | Inside_rearr | mDp4 |
| | | | rT1 |
| | | Positive_clone | C56C3 |
| | | | F57H12 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | 2_point (23) |
| | | Multi_point (163) |
| | | Pos_neg_data | 960 |
| | | | 966 |
| | | | 2735 |
| | | | 3702 |
| | | | 10659 |
| Reference (102) |
| Method | Gene |