WormBase Tree Display for Gene: WBGene00018646

WBGene00018646 SMap: S_parent: Sequence: F49F1
  Identity: Version: 2
    Name: CGC_name: mul-1 Paper_evidence: WBPaper00041533
      Sequence_name: F49F1.6
      Molecular_name: F49F1.6a
        F49F1.6a.1
        CE34873
        F49F1.6b
        CE50613
        F49F1.6b.1
      Other_name: CELE_F49F1.6 Accession_evidence: NDB BX284604
      Public_name: mul-1
    DB_info: Database: AceView gene 4E886
        WormQTL gene WBGene00018646
        WormFlux gene WBGene00018646
        NDB locus_tag CELE_F49F1.6
        Panther gene CAEEL|EnsemblGenome=WBGene00018646|UniProtKB=Q9GZE3
          family PTHR21724
        NCBI gene 186063
        RefSeq protein NM_068086.6
            NM_001313027.3
        TrEMBL UniProtAcc Q9GZE3
            A0A0K3AV21
        UniProt_GCRP UniProtAcc Q9GZE3
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 01 Feb 2013 15:26:07 WBPerson2970 Name_change: CGC_name: mul-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mul
    Allele (57)
    Strain: WBStrain00051577
      WBStrain00051576
    RNASeq_FPKM (74)
    GO_annotation: 00106385
    Ortholog (32)
    Paralog (63)
    Structured_description: Concise_description: mul-1 encodes a mucin-like protein containing a signal sequence and several ShK toxin domains; expression and phenotypic analyses suggest that mul-1 plays a role in response to stressors such as ionizing radiation, heavy metals, and bacterial infection; induction of mul-1 in response to ionizing radiation requires the ELT-2 GATA transcription factor and the p38 MAPK signaling pathway. Paper_evidence: WBPaper00028789
            WBPaper00030811
            WBPaper00032454
            WBPaper00041533
            WBPaper00041211
          Curator_confirmed: WBPerson1843
          Date_last_updated: 19 Feb 2014 00:00:00
      Automated_description: Involved in response to gamma radiation. Expressed in intestinal cell. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F49F1.6a
      F49F1.6b
    Corresponding_CDS_history: F49F1.6:wp105
    Corresponding_transcript: F49F1.6a.1
      F49F1.6b.1
    Other_sequence: NBC07566_1
      NB08827
    Associated_feature: WBsf651721
      WBsf229946
  Experimental_info: RNAi_result: WBRNAi00032560 Inferred_automatically: RNAi_primary
      WBRNAi00094587 Inferred_automatically: RNAi_primary
      WBRNAi00070140 Inferred_automatically: RNAi_primary
      WBRNAi00047881 Inferred_automatically: RNAi_primary
      WBRNAi00015345 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr14983
      Expr1021705
      Expr1151712
      Expr2013824
      Expr2032064
    Drives_construct: WBCnstr00026361
      WBCnstr00041832
      WBCnstr00042691
    Construct_product: WBCnstr00026361
      WBCnstr00042691
    Microarray_results (18)
    Expression_cluster: WBPaper00032022:X-Ray_upregulated
      WBPaper00032454:IR_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00036738:4uM_Heme_upregulated
      WBPaper00036738:500uM_Heme_upregulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_CoreEnriched
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:intestine_larva_SelectivelyEnriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00041075:hcf-1(-)_skn-1(+)_upregulated
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00042194:nhr-114(RNAi)_downregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044316:HgCl2_20uM_upregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045257:bar-1(ga80)_upregulated
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045401:N.parisii_30h_upregulated
      WBPaper00045401:N.parisii_40h_upregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00048926:miaserin_upregulated_adult-day10
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049498:npr-1(ur89)_regulated_5
      WBPaper00049635:dop-1(vs100)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00050096:P.aeruginosa_upregulated
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050561:indole_0.1mM-indole_upregulated
      WBPaper00050561:indole_10-fold_upregulated
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(icb38)_upregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:stavudine_72h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053318:mir-71(n4115)_upregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053664:ins-11(tm1053)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:OP50_vs_PY79_downregulated_PY79
      WBPaper00053909:N2_vs_CB4856_upregulated
      WBPaper00054410:set-26(tm2467)_upregulated
      WBPaper00054872:egl-9(sa307)_upregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055137:S.maltophilia_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056073:NHR-86_interacting_promoter
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:gut-microbiota_upregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056586:kri-1(ok1251);mpk-2(ok219)_downregulated
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057158:mdt-15(tm2182)_dependent_15C_downregulated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058948:PA14_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059253:stearic-acid_downregulated
      WBPaper00059253:sucrose_downregulated
      WBPaper00059253:sucrose_stearic-acid_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_upregulated
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059426:SiO2-nanoparticles_downregulated
      WBPaper00059477:lin-32(RNAi)_regulated
      WBPaper00059490:dcr-1(m9375)_upregulated
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060084:cco-1(RNAi)_upregulated_lin-40(yth27)
      WBPaper00060084:cco-1(RNAi)_upregulated_N2
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:CoCl2_6hr_upregulated_N2
      WBPaper00060661:hypoxia_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060764:swsn-1(os22ts)_upregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061319:pnp-1(jy90)_upregulated
      WBPaper00061319:pnp-1(jy121)_upregulated
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061390:daf-22(ok693)_ascarosides_downregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:C17H12.6-swt-6
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061590:CGP37157_upregulated
      WBPaper00061653:alh-4(hj221)_upregulated
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00061753:csr-1(tor159)_upregulated_20C
      WBPaper00061952:daf-18(nr2037)_upregulated
      WBPaper00062146:MOG-7-degron_2h_regulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062345:bortezomib_30min_upregulated_N2
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062497:xpf-1(tm2842)_upregulated
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064375:sid-1(pk3321)_regulated
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064632:daf-2(e1370)_downregulated_intestine
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_downregulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064871:P.fluorescens_upregulated_AWA
      WBPaper00064871:PA14-gacA()_upregulated_AWA
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065029:cadmium_upregulated
      WBPaper00065043:dcap-1(tm3163)_upregulated
      WBPaper00065086:JU1400_N.parisii_regulated
      WBPaper00065086:N2_N.parisii_regulated
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065392:Lb.delbrueckii_downregulated
      WBPaper00065392:Lb.gasseri_downregulated
      WBPaper00065392:Lb.plantarum_downregulated
      WBPaper00065392:Lb.reuteri_downregulated
      WBPaper00065392:Lb.rhamnosus_downregulated
      WBPaper00065392:P.pentosaceus_downregulated
      WBPaper00065823:pmk-1(km25)_downregulated
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065993:mml-1(RNAi)-neuron_upregulated
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00028789:PA14_vs_gacA_upregulated_4hr
      WBPaper00028789:PA14_vs_gacA_upregulated_8hr
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00028789:PA14_vs_OP50_upregulated_8hr
      WBPaper00031703:heme_responsive_5
      WBPaper00034739:N2lessDR1350
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035892:KIM5_vs_OP50_Up
      WBPaper00035892:Y.pestis_regulated
      WBPaper00036286:Pattern_D
      WBPaper00037113:Diazinon_16C_regulated
      WBPaper00037695:WC_5-day
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00039851:HK_C_albicans_vs_HK_OP50
      WBPaper00040184:hcf-1down_sir-2.1down_daf-2down
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040876:mir-35_downregulated
      WBPaper00040963:TA200_down
      WBPaper00040963:TA300_down
      WBPaper00041211:RPW-24_Up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041609:hpl-1_hpl-2_upregulated
      WBPaper00041906:I-4317_vs_OP50_10d
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00042128:gei-8(ok1671)_upregulated
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00043980:arsenic_upregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045294:50uM_TBBP_upregulated
      WBPaper00045401:N.parisii_34h_upregulated_N2
      WBPaper00045673:colistin_upregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00051448:P.aeruginosa_Slow-Killing_upregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
    Interaction (15)
    WBProcess: WBbiopr:00000039
      WBbiopr:00000092
  Map_info: Map: IV Position: -0.670788
    Positive: Positive_clone: F49F1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00028789
    WBPaper00031923
    WBPaper00032022
    WBPaper00032331
    WBPaper00032454
    WBPaper00035891
    WBPaper00041211
    WBPaper00041533
    WBPaper00044217
    WBPaper00057562
    WBPaper00059433
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene