WormBase Tree Display for Gene: WBGene00017816

WBGene00017816 SMap: S_parent: Sequence: F26B1
  Identity: Version: 2
    Name: CGC_name: hrpk-1 Person_evidence: WBPerson2506
      Sequence_name: F26B1.2
      Molecular_name (19)
      Other_name: CELE_F26B1.2 Accession_evidence: NDB BX284601
      Public_name: hrpk-1
    DB_info: Database: AceView gene 1G895
        WormQTL gene WBGene00017816
        WormFlux gene WBGene00017816
        NDB locus_tag CELE_F26B1.2
        Panther gene CAEEL|WormBase=WBGene00017816|UniProtKB=P91277
          family PTHR10288
        NCBI gene 172330
        RefSeq protein NM_001392429.1
            NM_001392433.1
            NM_001392432.1
            NM_001392431.1
            NM_170880.6
        SwissProt UniProtAcc P91277
        TREEFAM TREEFAM_ID TF316335
        UniProt_GCRP UniProtAcc P91277
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:59 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 04 Jan 2016 15:29:00 WBPerson2970 Name_change: CGC_name: hrpk-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: hrpk
    Allele (36)
    Possibly_affected_by: WBVar02152928
    Strain: WBStrain00037915
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (46)
    Paralog: WBGene00003978 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00007534 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00010908 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013347 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00015557 Caenorhabditis elegans From_analysis: Panther
      WBGene00016489 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00019692 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00022738 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00022737 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable mRNA binding activity. Involved in DNA damage response and embryo development. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including hypodermal cell; intestinal cell; muscle cell; neurons; and oocyte. Human ortholog(s) of this gene implicated in Raynaud disease; colorectal cancer; and prostate cancer. Is an ortholog of human HNRNPK (heterogeneous nuclear ribonucleoprotein K). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9256 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5044)
      DOID:10283 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5044)
      DOID:10300 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5044)
  Molecular_info: Corresponding_CDS: F26B1.2a
      F26B1.2b
      F26B1.2c
      F26B1.2d
      F26B1.2e
    Corresponding_CDS_history: F26B1.2b:wp90
    Corresponding_transcript: F26B1.2a.1
      F26B1.2b.1
      F26B1.2b.2
      F26B1.2b.3
      F26B1.2b.4
      F26B1.2c.1
      F26B1.2d.1
      F26B1.2d.2
      F26B1.2e.1
    Other_sequence (71)
    Associated_feature: WBsf643356
      WBsf983891
      WBsf983892
      WBsf217794
      WBsf217795
      WBsf217796
      WBsf217797
  Experimental_info: RNAi_result: WBRNAi00115203 Inferred_automatically: RNAi_primary
      WBRNAi00077903 Inferred_automatically: RNAi_primary
      WBRNAi00111647 Inferred_automatically: RNAi_primary
      WBRNAi00045597 Inferred_automatically: RNAi_primary
      WBRNAi00116469 Inferred_automatically: RNAi_primary
      WBRNAi00031429 Inferred_automatically: RNAi_primary
      WBRNAi00003476 Inferred_automatically: RNAi_primary
      WBRNAi00007753 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr14889
      Expr14890
      Expr14891
      Expr14892
      Expr1011487
      Expr1037656
      Expr1149507
      Expr2012603
      Expr2030839
    Drives_construct: WBCnstr00026993
    Construct_product: WBCnstr00026993
    Regulate_expr_cluster: WBPaper00058673:hrpk-1(tm5522)_downregulated_miRNA_L4
      WBPaper00058673:hrpk-1(tm5522)_upregulated_miRNA_L4
      WBPaper00058673:hrpk-1(zen17)_downregulated_miRNA_embryo
      WBPaper00058673:hrpk-1(zen17)_downregulated_miRNA_L4
      WBPaper00058673:hrpk-1(zen17)_upregulated_miRNA_embryo
      WBPaper00058673:hrpk-1(zen17)_upregulated_miRNA_L4
    Antibody: WBAntibody00002880
    Microarray_results (52)
    Expression_cluster: WBPaper00027057:DCR-1_interacting_embryo
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032425:up_in_zfp-1
      WBPaper00035269:cde-1_regulated
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038118:stress_upregulated_N2
      WBPaper00038289:oocyte_protein
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(gk119)_downregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050599:nicotine(0.01mM)_upregulated
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:downregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00053810:clk-1(qm30)_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00053814:25C_downregulated_PY79
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:germline_expressed
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056284:ints-5(RNAi)_downregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00059254:WAGO-1_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061045:Y56A3A.22(cck200)_downregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061274:microgravity_upregulated
      WBPaper00061340:Z1_Z4
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061466:nath-10(icb99)_upregulated
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061527:npp-8_4368-E01B7.1_7741
      WBPaper00061527:tomm-40_3370-eif-3.C_3529
      WBPaper00061902:CAMT-1_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00063930:BRD-1_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064080:let-7_miRNA_interacting
      WBPaper00064080:miR-58_miRNA_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064201:SNA-3_interacting
      WBPaper00064315:mes-3(bn199)_downregulated_EGCs
      WBPaper00064315:mes-4(bn73)_downregulated_EGCs
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064716:paraquat_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4386_cluster_6_3
      cgc4489_group_2
      WBPaper00025032:cluster_34
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027342:alpha-Synuclein(WT)_upregulated
      WBPaper00031060:2-deoxy-D-glucose_downregulated
      WBPaper00031832:slr-2_regulated
      WBPaper00032948:FedUp
      WBPaper00034661:AgNPs_upregulated
      WBPaper00034739:N2moreDR1350
      WBPaper00035905:FBF-1_Associated
      WBPaper00037695:DD_3-day
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_3h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045673:colistin_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:cluster_44
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_E_pi(122_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MDE
      [cgc5767]:expression_class_MD_pd(41_min)
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_F
      [cgc6390]:oogenesis-enriched
    SAGE_tag: SAGE:ggcgttgaat Strand: Antisense
      SAGE:aagcgagagcacgataa Strand: Sense
        Unambiguously_mapped
      SAGE:tccaagtccc Strand: Sense
        Unambiguously_mapped
      SAGE:gccttcggac Strand: Antisense
      SAGE:aatgcgtatt Strand: Antisense
    Interaction (205)
  Map_info: Map: I Position: 0.985507
    Positive: Positive_clone: F26B1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (12)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene