WormBase Tree Display for Gene: WBGene00015752

WBGene00015752 SMap: S_parent: Sequence: C14B9
  Identity: Version: 1
    Name: Sequence_name: C14B9.2
      Molecular_name: C14B9.2
        C14B9.2.1
        CE30601
      Other_name: CELE_C14B9.2 Accession_evidence: NDB BX284603
      Public_name: C14B9.2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (32)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (37)
    Paralog (13)
    Structured_description: Concise_description: C14B9.2 encodes a protein disulfide isomerase; by homology, the product of C14B9.2 is predicted to function in oxidative protein folding in the endoplasmic reticulum (ER); C14B9.2 transcript levels are increased in response to ER stress. Paper_evidence: WBPaper00005432
          Curator_confirmed: WBPerson1843
          Date_last_updated: 07 Apr 2011 00:00:00
      Automated_description: Predicted to enable protein disulfide isomerase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in cell surface and endoplasmic reticulum. Is an ortholog of human PDIA4 (protein disulfide isomerase family A member 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C14B9.2
    Corresponding_transcript: C14B9.2.1
    Other_sequence (75)
    Associated_feature: WBsf645388
      WBsf659228
      WBsf659229
      WBsf659230
      WBsf225352
      WBsf225353
  Experimental_info: RNAi_result: WBRNAi00033251 Inferred_automatically: RNAi_primary
      WBRNAi00069750 Inferred_automatically: RNAi_primary
      WBRNAi00076124 Inferred_automatically: RNAi_primary
      WBRNAi00000322 Inferred_automatically: RNAi_primary
      WBRNAi00040505 Inferred_automatically: RNAi_primary
      WBRNAi00010732 Inferred_automatically: RNAi_primary
      WBRNAi00069749 Inferred_automatically: RNAi_primary
      WBRNAi00005199 Inferred_automatically: RNAi_primary
      WBRNAi00027173 Inferred_automatically: RNAi_primary
      WBRNAi00024552 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1022760
      Expr1036741
      Expr1144569
      Expr2000772
      Expr2018993
    Drives_construct: WBCnstr00028595
    Construct_product: WBCnstr00028595
    Microarray_results (24)
    Expression_cluster: WBPaper00005432:xbp-1(zc12)_downregulated
      WBPaper00024505:pharyngeal_enriched
      WBPaper00028451:Oogenic_protein
      WBPaper00032425:up_in_alg-1
      WBPaper00032528:L3_enriched
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00038289:oocyte_protein
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044260:1-methylnicotinamide_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044746:aging_downregulated_Day5
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045521:Spermatogenic
      WBPaper00045971:tunicamycin_upregulated_control
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00049954:BPS_upregulated
      WBPaper00050094:mes-6(bn66)_upregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_downregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051305:vit-2(ac3)_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00052987:UV_downregulated_xpc-1;csb-1
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053599:mitosis_vs_meiosis_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053814:25C_upregulated_OP50
      WBPaper00053814:25C_upregulated_PY79
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056284:ints-1(RNAi)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058801:ceh-60(lst466)_upregulated_protein
      WBPaper00059373:stt-3(RNAi)_upregulated
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060224:atf-6(ok551)_upregulated
      WBPaper00060434:pH4.33_vs_pH6.33_downrgulated
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060908:TEBP-2_interacting
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:g1A_g1P
      WBPaper00061340:g1A_parent
      WBPaper00061340:g2
      WBPaper00061340:g2_parent
      WBPaper00061340:M1_parent
      WBPaper00061340:mc1
      WBPaper00061340:mc2
      WBPaper00061340:mc3
      WBPaper00061340:Neuroblast_M2_M3
      WBPaper00061340:Parent_of_g1P_I3
      WBPaper00061340:Pharyngeal_intestinal_valve
      WBPaper00061340:Pharyngeal_marginal_cell
      WBPaper00061340:Pharyngeal_neuron
      WBPaper00061340:pm1_pm2
      WBPaper00061340:pm3_pm4_pm5
      WBPaper00061340:pm6
      WBPaper00061340:pm7
      WBPaper00061340:pm8
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061479:hrde-1(tm1200)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:mlt-9_22518-F33D4.6_14044
      WBPaper00061527:T24C12.3-C01G10.9
      WBPaper00061853:osm-3(dh441)_upregulated_tunicamycin
      WBPaper00061853:tunicamycin_downregulated_N2
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064789:Day12_vs_Day1_upregulated_neuron
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00064952:Day5_vs_L4_downregulated_20C
      WBPaper00064952:Day5_vs_L4_downregulated_25C
      WBPaper00064952:Day10_vs_L4_downregulated_20C
      WBPaper00064952:Day10_vs_L4_downregulated_25C
      WBPaper00065029:cadmium_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065841:24_1
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      cgc4386_cluster_5_3
      cgc4489_group_8
      WBPaper00025032:cluster_12
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_A
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030985:Erwinia_carotovora_upregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031184:acrylamide_downregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032165:differentially_expressed_with_age_medoid_1
      WBPaper00034739:N2lessDR1350
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_C
      WBPaper00036383:ash-2_Day8_regulated
      WBPaper00037695:LD_3-day
      WBPaper00040210:Chlorpyrifos_16C_regulated
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041207:CE_dauer_down
      WBPaper00041211:RPW-24_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00056330:mrps-5(RNAi)_upregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:cluster_2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(66_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_C
    Interaction (92)
  Map_info: Positive: Positive_clone: C14B9 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III -0.37624
  Reference: WBPaper00005432
    WBPaper00026830
    WBPaper00030802
    WBPaper00038491
    WBPaper00041408
    WBPaper00055090
  Method: Gene