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WormBase Tree Display for Gene: WBGene00015467

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Name Class

WBGene00015467SMapS_parentSequenceC05D2
IdentityVersion2
NameCGC_namebasl-1Paper_evidenceWBPaper00024422
Person_evidenceWBPerson384
WBPerson260
Sequence_nameC05D2.3
Molecular_nameC05D2.3
C05D2.3.1
CE29022
Other_nameCELE_C05D2.3Accession_evidenceNDBBX284603
Public_namebasl-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
202 Mar 2012 16:42:47WBPerson2970Name_changeCGC_namebasl-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classbasl
Allele (38)
StrainWBStrain00031578
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (41)
ParalogWBGene00000239Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00001839Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00006409Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00006562Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00017392Caenorhabditis elegansFrom_analysismodENCODE_Pseudogenes
WBGene00004981Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00006418Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00006762Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00007593Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022427Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionC05D2.3 generally resembles aromatic-L-amino-acid/L-histidine decarboxylases; however, its predicted protein sequence lacks six residues critical for AADC function.Paper_evidenceWBPaper00004403
WBPaper00004651
WBPaper00006395
Person_evidenceWBPerson384
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated05 Aug 2011 00:00:00
Automated_descriptionPredicted to enable aromatic-L-amino-acid decarboxylase activity. Predicted to be involved in catecholamine metabolic process and serotonin biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including aromatic L-amino acid decarboxylase deficiency; bipolar disorder; and hyperinsulinism. Is an ortholog of human DDC (dopa decarboxylase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3312Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2719)
DOID:0090123Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2719)
DOID:14330Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2719)
DOID:655Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2719)
DOID:2018Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2719)
Molecular_infoCorresponding_CDSC05D2.3
Corresponding_transcriptC05D2.3.1
Associated_featureWBsf992455
WBsf992456
WBsf992457
WBsf992458
WBsf992459
WBsf1014917
WBsf1014918
WBsf1014919
WBsf1014920
WBsf224970
Experimental_infoRNAi_resultWBRNAi00005120Inferred_automaticallyRNAi_primary
WBRNAi00000720Inferred_automaticallyRNAi_primary
WBRNAi00022274Inferred_automaticallyRNAi_primary
WBRNAi00039750Inferred_automaticallyRNAi_primary
Expr_patternExpr1020655
Expr1143842
Expr2009532
Expr2027769
Drives_constructWBCnstr00028824
Construct_productWBCnstr00028824
Microarray_results (22)
Expression_cluster (162)
InteractionWBInteraction000342557
WBInteraction000500584
Map_infoMapIIIPosition-1.46902
PositivePositive_cloneC05D2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00016920
WBPaper00017338
WBPaper00023952
WBPaper00024422
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene