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WormBase Tree Display for Gene: WBGene00011045

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Name Class

WBGene00011045SMapS_parentSequenceR05H10
IdentityVersion2
NameCGC_namegpx-2Person_evidenceWBPerson261
Sequence_nameR05H10.5
Molecular_nameR05H10.5a
R05H10.5a.1
CE18107
R05H10.5b
CE48951
R05H10.5b.1
Other_nameCELE_R05H10.5Accession_evidenceNDBBX284602
Public_namegpx-2
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
220 Jul 2012 14:20:02WBPerson2970Name_changeCGC_namegpx-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpx
Allele (74)
RNASeq_FPKM (74)
GO_annotation (12)
Contained_in_operonCEOP2652
Ortholog (40)
ParalogWBGene00007516Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00007517Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00009165Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00020373Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00022377Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00018850Caenorhabditis elegansFrom_analysisPanther
WBGene00019846Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple) and spondylometaphyseal dysplasia Sedaghatian type. Is an ortholog of human GPX4 (glutathione peroxidase 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9256Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4556)
DOID:3717Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4556)
DOID:1184Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4556)
DOID:219Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4556)
DOID:10591Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4556)
DOID:0112298Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4556)
DOID:0050861Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4556)
Molecular_infoCorresponding_CDSR05H10.5a
R05H10.5b
Corresponding_transcriptR05H10.5a.1
R05H10.5b.1
Other_sequence (130)
Associated_featureWBsf658446
WBsf658447
WBsf222518
Experimental_infoRNAi_resultWBRNAi00051338Inferred_automaticallyRNAi_primary
WBRNAi00034637Inferred_automaticallyRNAi_primary
Expr_patternExpr1010923
Expr1034846
Expr1155031
Expr2012216
Expr2030452
Microarray_results (23)
Expression_cluster (107)
SAGE_tagSAGE:cgagatcgatatcgccgStrandSense
Unambiguously_mapped
SAGE:atggttcctgaccaccgStrandAntisense
SAGE:cgagatcgatStrandSense
Unambiguously_mapped
Interaction (114)
Map_infoMapIIPosition23.663
PositivePositive_cloneR05H10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00042257
WBPaper00044578
WBPaper00045706
WBPaper00055090
WBPaper00060484
WBPaper00061220
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene