WormBase Tree Display for Gene: WBGene00011045

WBGene00011045 SMap: S_parent: Sequence: R05H10
  Identity: Version: 2
    Name: CGC_name: gpx-2 Person_evidence: WBPerson261
      Sequence_name: R05H10.5
      Molecular_name: R05H10.5a
        R05H10.5a.1
        CE18107
        R05H10.5b
        CE48951
        R05H10.5b.1
      Other_name: CELE_R05H10.5 Accession_evidence: NDB BX284602
      Public_name: gpx-2
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:52 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 20 Jul 2012 14:20:02 WBPerson2970 Name_change: CGC_name: gpx-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gpx
    Allele (74)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Contained_in_operon: CEOP2652
    Ortholog (40)
    Paralog: WBGene00007516 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00007517 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00009165 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00020373 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00022377 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018850 Caenorhabditis elegans From_analysis: Panther
      WBGene00019846 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple) and spondylometaphyseal dysplasia Sedaghatian type. Is an ortholog of human GPX4 (glutathione peroxidase 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9256 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4556)
      DOID:3717 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4556)
      DOID:1184 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4556)
      DOID:219 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4556)
      DOID:10591 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4556)
      DOID:0112298 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4556)
      DOID:0050861 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4556)
  Molecular_info: Corresponding_CDS: R05H10.5a
      R05H10.5b
    Corresponding_transcript: R05H10.5a.1
      R05H10.5b.1
    Other_sequence (130)
    Associated_feature: WBsf658446
      WBsf658447
      WBsf222518
  Experimental_info: RNAi_result: WBRNAi00051338 Inferred_automatically: RNAi_primary
      WBRNAi00034637 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1010923
      Expr1034846
      Expr1155031
      Expr2012216
      Expr2030452
    Microarray_results (23)
    Expression_cluster (107)
    SAGE_tag: SAGE:cgagatcgatatcgccg Strand: Sense
        Unambiguously_mapped
      SAGE:atggttcctgaccaccg Strand: Antisense
      SAGE:cgagatcgat Strand: Sense
        Unambiguously_mapped
    Interaction: WBInteraction000042231
      WBInteraction000046254
      WBInteraction000046313
      WBInteraction000111164
      WBInteraction000111191
      WBInteraction000111783
      WBInteraction000112029
      WBInteraction000112082
      WBInteraction000112471
      WBInteraction000112474
      WBInteraction000112543
      WBInteraction000113335
      WBInteraction000113601
      WBInteraction000116094
      WBInteraction000116218
      WBInteraction000118173
      WBInteraction000118247
      WBInteraction000119125
      WBInteraction000122259
      WBInteraction000124082
      WBInteraction000125689
      WBInteraction000133668
      WBInteraction000133719
      WBInteraction000143916
      WBInteraction000144715
      WBInteraction000156851
      WBInteraction000156897
      WBInteraction000161443
      WBInteraction000170992
      WBInteraction000179012
      WBInteraction000180153
      WBInteraction000187914
      WBInteraction000189488
      WBInteraction000191646
      WBInteraction000199933
      WBInteraction000203297
      WBInteraction000210878
      WBInteraction000217312
      WBInteraction000219506
      WBInteraction000219508
      WBInteraction000228242
      WBInteraction000228243
      WBInteraction000230853
      WBInteraction000231472
      WBInteraction000231482
      WBInteraction000237510
      WBInteraction000242164
      WBInteraction000248294
      WBInteraction000257940
      WBInteraction000259072
      WBInteraction000259073
      WBInteraction000263732
      WBInteraction000272365
      WBInteraction000283789
      WBInteraction000285337
      WBInteraction000301477
      WBInteraction000312738
      WBInteraction000344110
      WBInteraction000348487
      WBInteraction000351052
      WBInteraction000357266
      WBInteraction000357535
      WBInteraction000366675
      WBInteraction000384867
      WBInteraction000384868
      WBInteraction000391786
      WBInteraction000396421
      WBInteraction000397277
      WBInteraction000418565
      WBInteraction000423628
      WBInteraction000444492
      WBInteraction000444799
      WBInteraction000449220
      WBInteraction000453005
      WBInteraction000458706
      WBInteraction000461687
      WBInteraction000462768
      WBInteraction000464899
      WBInteraction000465294
      WBInteraction000465553
      WBInteraction000465947
      WBInteraction000466329
      WBInteraction000468234
      WBInteraction000468248
      WBInteraction000468955
      WBInteraction000469377
      WBInteraction000469532
      WBInteraction000470052
      WBInteraction000471344
      WBInteraction000471783
      WBInteraction000472422
      WBInteraction000472617
      WBInteraction000472952
      WBInteraction000472995
      WBInteraction000473225
      WBInteraction000473601
      WBInteraction000474537
      WBInteraction000474927
      WBInteraction000474941
      WBInteraction000475143
      WBInteraction000475394
      WBInteraction000475403
      WBInteraction000524483
      WBInteraction000542793
      WBInteraction000552137
      WBInteraction000554422
      WBInteraction000554591
      WBInteraction000557802
      WBInteraction000562975
      WBInteraction000572021
      WBInteraction000577001
      WBInteraction000577926
      WBInteraction000580738
      WBInteraction000586410
  Map_info: Map: II Position: 23.663
    Positive: Positive_clone: R05H10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00042257
    WBPaper00044578
    WBPaper00045706
    WBPaper00055090
    WBPaper00060484
    WBPaper00061220
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene