Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00007516

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00007516SMapS_parentSequenceC11E4
IdentityVersion2
NameCGC_namegpx-5Person_evidenceWBPerson261
Sequence_nameC11E4.1
Molecular_nameC11E4.1
C11E4.1.1
CE08101
Other_nameCELE_C11E4.1Accession_evidenceNDBBX284606
Public_namegpx-5
DB_infoDatabaseAceViewgeneXK203
WormQTLgeneWBGene00007516
WormFluxgeneWBGene00007516
NDBlocus_tagCELE_C11E4.1
PanthergeneCAEEL|WormBase=WBGene00007516|UniProtKB=Q93204
familyPTHR11592
NCBIgene181178
RefSeqproteinNM_077214.6
TREEFAMTREEFAM_IDTF105318
TrEMBLUniProtAccQ93204
UniProt_GCRPUniProtAccQ93204
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:48WBPerson1971EventImportedInitial conversion from CDS class of WS125
220 Jul 2012 14:20:02WBPerson2970Name_changeCGC_namegpx-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpx
Allele (33)
StrainWBStrain00002595
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (55)
ParalogWBGene00009165Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00007517Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00011045Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00020373Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00022377Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00018850Caenorhabditis elegansFrom_analysisPanther
WBGene00019846Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptiongpx-5 encodes a glutathione peroxidase; by homology, GPX-5 is predicted to function to reduce lipid hydroperoxides to their corresponding alcohols and reduce hydrogen peroxide to water to protect cells from damage induced by reactive oxygen species.Curator_confirmedWBPerson1843
Date_last_updated28 May 2014 00:00:00
Automated_descriptionPredicted to enable glutathione peroxidase activity. Involved in response to reactive oxygen species. Predicted to be located in extracellular space. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of human GPX3 (glutathione peroxidase 3) and GPX5 (glutathione peroxidase 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (67)
Molecular_infoCorresponding_CDSC11E4.1
Corresponding_CDS_historyC11E4.1:wp83
C11E4.1:wp178
Corresponding_transcriptC11E4.1.1
Other_sequence (80)
Associated_featureWBsf648418
WBsf663182
WBsf663183
WBsf1006478
WBsf1006479
WBsf1023593
WBsf236183
Experimental_infoRNAi_resultWBRNAi00040349Inferred_automaticallyRNAi_primary
WBRNAi00091322Inferred_automaticallyRNAi_primary
WBRNAi00040350Inferred_automaticallyRNAi_primary
WBRNAi00010619Inferred_automaticallyRNAi_primary
WBRNAi00028806Inferred_automaticallyRNAi_primary
WBRNAi00115577Inferred_automaticallyRNAi_primary
WBRNAi00115502Inferred_automaticallyRNAi_primary
Expr_patternChronogram759
Expr5242
Expr1028068
Expr1033235
Expr1144416
Expr2012219
Expr2030455
Drives_constructWBCnstr00003154
WBCnstr00033683
Construct_productWBCnstr00033683
Microarray_results (17)
Expression_cluster (260)
InteractionWBInteraction000114668
WBInteraction000155203
WBInteraction000519745
WBInteraction000542764
WBInteraction000552146
Map_infoMapXPosition1.42294
PositivePositive_cloneC11E4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00032037
WBPaper00038491
WBPaper00039791
WBPaper00042257
WBPaper00042271
WBPaper00045706
WBPaper00055090
WBPaper00061220
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene