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WormBase Tree Display for Gene: WBGene00009180

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Name Class

WBGene00009180SMapS_parentSequenceF26H11
IdentityVersion3
NameCGC_namenurf-1Person_evidenceWBPerson1730
WBPerson268
Sequence_nameF26H11.2
Molecular_name (57)
Other_nameCELE_F26H11.2Accession_evidenceNDBBX284602
Public_namenurf-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
201 Jul 2004 15:37:03WBPerson1983EventAcquires_mergeWBGene00009181
309 Sep 2005 11:06:53WBPerson2970Name_changeCGC_namenurf-1
Acquires_mergeWBGene00009181
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnurf
Allele (462)
Possibly_affected_byWBVar02152867
StrainWBStrain00027435
WBStrain00027440
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (47)
ParalogWBGene00001470Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00010199Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00017423Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00019217Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021636Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022473Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionnurf-1 encodes the C. elegans ortholog of Drosophila NURF301, a component of the NURF chromatin remodeling complex; in C. elegans, nurf-1 acts with isw-1 to regulate vulval development.Paper_evidenceWBPaper00027681
Curator_confirmedWBPerson1843
Date_last_updated31 Aug 2011 00:00:00
Automated_descriptionPredicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and methylated histone binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NURF complex. Expressed in several structures, including head; pharyngeal-intestinal valve; pharynx; tail; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease and amyotrophic lateral sclerosis. Is an ortholog of human BPTF (bromodomain PHD finger transcription factor).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3581)
DOID:0070514Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3581)
DOID:332Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3581)
Molecular_infoCorresponding_CDS (17)
Corresponding_CDS_historyF26H11.2a:wp108
F26H11.2a:wp229
F26H11.2b:wp108
F26H11.2b:wp229
F26H11.2c:wp229
F26H11.2d:wp188
F26H11.2g:wp274
F26H11.2h:wp274
Corresponding_transcript (23)
Other_sequence (22)
Associated_feature (34)
Transcription_factorWBTranscriptionFactor000776
Experimental_infoRNAi_result (36)
Expr_pattern (11)
Drives_constructWBCnstr00012667
WBCnstr00014344
WBCnstr00014346
WBCnstr00014347
WBCnstr00014348
WBCnstr00014362
Construct_productWBCnstr00016587
WBCnstr00016607
Microarray_results (72)
Expression_cluster (198)
SAGE_tag (16)
Interaction (36)
Map_infoMapIIPosition22.9649Error0.001067
PositivePositive_cloneF26H11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (16)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene