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WormBase Tree Display for Gene: WBGene00008601

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Name Class

WBGene00008601SMapS_parentSequenceCHROMOSOME_X
IdentityVersion2
NameCGC_namemob-2
Sequence_nameF09A5.4
Molecular_name (20)
Other_namemob-1Paper_evidenceWBPaper00050583
CELE_F09A5.4Accession_evidenceNDBBX284606
Public_namemob-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
205 Apr 2017 11:17:23WBPerson2970Name_changeCGC_namemob-2
Other_namemob-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmob
Allele (310)
StrainWBStrain00033070
RNASeq_FPKM (74)
GO_annotation00008693
00008694
00008695
00008696
00008697
00012482
00012483
Ortholog (35)
ParalogWBGene00020447Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00016238Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00009551Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionF09A5.4 encodes one of three C. elegans proteins orthologous to members of the MOB (Mps One Binder) family of proteins, a group of highly conserved proteins that function as binding partners and co-activators of NDR/LATS protein kinases; in metazoans, MOB proteins are core components of the Hippo signaling pathway that regulates cell proliferation and survival.Paper_evidenceWBPaper00005453
Curator_confirmedWBPerson1843
Date_last_updated22 Feb 2013 00:00:00
Automated_descriptionPredicted to enable protein kinase activator activity. Predicted to be involved in positive regulation of protein phosphorylation and signal transduction. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human MOB2 (MOB kinase activator 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF09A5.4a
F09A5.4b
F09A5.4c
F09A5.4d
F09A5.4e
F09A5.4g
Corresponding_CDS_historyF09A5.4f:wp121
Corresponding_transcriptF09A5.4f
F09A5.4a.1
F09A5.4b.1
F09A5.4b.2
F09A5.4c.1
F09A5.4d.1
F09A5.4e.1
F09A5.4g.1
Other_sequence (58)
Associated_feature (48)
Experimental_infoRNAi_resultWBRNAi00012945Inferred_automaticallyRNAi_primary
WBRNAi00030684Inferred_automaticallyRNAi_primary
WBRNAi00078440Inferred_automaticallyRNAi_primary
WBRNAi00044072Inferred_automaticallyRNAi_primary
Expr_patternExpr1011218
Expr1033746
Expr1148037
Expr2013638
Expr2031872
Drives_constructWBCnstr00032838
Construct_productWBCnstr00032838
Microarray_results (61)
Expression_clusterWBPaper00032031:DConiospora_downregulated_cDNA_12h
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037055:DAF-16_binding_DNA
WBPaper00037946:LIN-39_interacting
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
WBPaper00040209:B.thuringiensis_downregulated_MY15
WBPaper00040221:DAF-12_target_ALF4
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00044786:lem-2(tm1582)_upregulated
WBPaper00045390:ubc-9(RNAi)_downregulated
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Oogenic
WBPaper00045971:tunicamycin_upregulated_control
WBPaper00045971:tunicamycin_upregulated_RtcB(null)
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050015:ifg-1(RNAi)_upregulated
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:intestine_specific
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053599:female_vs_male_upregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00056139:soil-microbiota_upregulated
WBPaper00056161:hermaphrodite_enriched_siRNA
WBPaper00056275:P.aeruginosa_downregulated
WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056855:his-72(uge40)_downregulated
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058948:PA14_downregulated
WBPaper00058958:100mGy-irradiation-72h_upregulated
WBPaper00059027:neuron-synapses_depleted
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059471:EGL-43_interacting
WBPaper00059605:MUT-16_interacting
WBPaper00060459:bcat-1(RNAi)_upregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061340:ADL_parent
WBPaper00061340:ASK_parent
WBPaper00061340:Neuroblast_AFD_RMD
WBPaper00061340:Neuroblast_HSN_PHB
WBPaper00061340:Parent_of_exc_gland_AVK
WBPaper00061340:Parent_of_K_Kprime
WBPaper00061340:pm6
WBPaper00061466:nath-10(icb102)_upregulated
WBPaper00061527:cdc-42_17192-rab-5_18073
WBPaper00061651:PHA_enriched
WBPaper00062156:jmjd-5(zr1234)_upregulated_germline
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:etr-1(lq61)_downregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064871:hypoxia_downregulated_F2
WBPaper00065120:body-muscle-transcriptome
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00066085:hda-3(ok1991)_upregulated
cgc4386_cluster_4_4
WBPaper00025032:cluster_30
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00029437:dcr-1_upregulated
WBPaper00030985:Enterococcus_faecalis_downregulated
WBPaper00031252:AIN-1_IP_enriched
WBPaper00031252:AIN-2_IP_enriched
WBPaper00031532:Larva_Pan_Neuronal_Depleted
WBPaper00031832:slr-2_regulated
WBPaper00031850:mdt-15(RNAi)_upregulated
WBPaper00034739:N2moreDR1350
WBPaper00035084:L3_enriched_AIN-2_IP
WBPaper00035227:heat_shock_regulated
WBPaper00036123:Atrazine_regulated
WBPaper00036123:Cadmium_regulated
WBPaper00037113:Diazinon_16C_regulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_aging
WBPaper00040858:eQTL_regulated_developing
WBPaper00040858:eQTL_regulated_juvenile
WBPaper00040858:eQTL_regulated_old
WBPaper00040858:eQTL_regulated_reproductive
WBPaper00040985:AIN-2_asynchronous_intestine
WBPaper00040985:AIN-2_L4_intestine
WBPaper00041002:HQ_3d_2.0mM_Up
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00042548:miRISC_enriched
WBPaper00045960:L4-lethargus_upregulated
WBPaper00047070:N2_starvation_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(53_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
[cgc6390]:Cluster_A
InteractionWBInteraction000547713
Map_infoMapXPosition10.2171
PositivePositive_cloneF09A5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005453
WBPaper00038491
WBPaper00047915
WBPaper00055090
WBPaper00064898
Remarkmob-1 was previously associated with F38H4.10Paper_evidenceWBPaper00050583
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene