WormBase Tree Display for Gene: WBGene00007516

WBGene00007516 SMap: S_parent: Sequence: C11E4
  Identity: Version: 2
    Name: CGC_name: gpx-5 Person_evidence: WBPerson261
      Sequence_name: C11E4.1
      Molecular_name: C11E4.1
        C11E4.1.1
        CE08101
      Other_name: CELE_C11E4.1 Accession_evidence: NDB BX284606
      Public_name: gpx-5
    DB_info: Database: AceView gene XK203
        WormQTL gene WBGene00007516
        WormFlux gene WBGene00007516
        NDB locus_tag CELE_C11E4.1
        Panther gene CAEEL|WormBase=WBGene00007516|UniProtKB=Q93204
          family PTHR11592
        NCBI gene 181178
        RefSeq protein NM_077214.6
        TREEFAM TREEFAM_ID TF105318
        TrEMBL UniProtAcc Q93204
        UniProt_GCRP UniProtAcc Q93204
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 20 Jul 2012 14:20:02 WBPerson2970 Name_change: CGC_name: gpx-5
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gpx
    Allele (33)
    Strain: WBStrain00002595
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog: WBGene00120043 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00081886 Caenorhabditis remanei From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00154393 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00140267 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00160318 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00140930 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00164475 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00160692 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00139814 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00132958 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00123508 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00078957 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00079896 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00059450 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00084782 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00036144 Caenorhabditis briggsae From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00110190 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00222412 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g11936 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g12502 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g1443 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g21560 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g9437 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g15350 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g7104 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g5457 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g10607 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g4747 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00044.g2378 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_X.g22671 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g13469 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00008.g591 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_02215 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_023325 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g07592 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g16860 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0056700 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g19764 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00267356 Strongyloides ratti From_analysis: WormBase-Compara
      ZFIN:ZDB-GENE-030410-1 Danio rerio From_analysis: EnsEMBL-Compara
            OMA
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-070222-3 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      HGNC:4553 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:4554 Homo sapiens From_analysis: EnsEMBL-Compara
            OMA
            OrthoInspector
            Panther
      HGNC:4555 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      HGNC:4557 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      HGNC:4558 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            SonicParanoid
      MGI:104887 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      MGI:106609 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            OrthoInspector
            Panther
      MGI:105102 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      MGI:104886 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      MGI:1922762 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      RGD:2729 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      RGD:69224 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      RGD:69227 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      RGD:628789 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
    Paralog: WBGene00009165 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00007517 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00011045 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00020373 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00022377 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018850 Caenorhabditis elegans From_analysis: Panther
      WBGene00019846 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: gpx-5 encodes a glutathione peroxidase; by homology, GPX-5 is predicted to function to reduce lipid hydroperoxides to their corresponding alcohols and reduce hydrogen peroxide to water to protect cells from damage induced by reactive oxygen species. Curator_confirmed: WBPerson1843
          Date_last_updated: 28 May 2014 00:00:00
      Automated_description: Predicted to enable glutathione peroxidase activity. Involved in response to reactive oxygen species. Predicted to be located in extracellular space. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of human GPX3 (glutathione peroxidase 3) and GPX5 (glutathione peroxidase 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (67)
  Molecular_info: Corresponding_CDS: C11E4.1
    Corresponding_CDS_history: C11E4.1:wp83
      C11E4.1:wp178
    Corresponding_transcript: C11E4.1.1
    Other_sequence (80)
    Associated_feature: WBsf648418
      WBsf663182
      WBsf663183
      WBsf1006478
      WBsf1006479
      WBsf1023593
      WBsf236183
  Experimental_info: RNAi_result: WBRNAi00040349 Inferred_automatically: RNAi_primary
      WBRNAi00091322 Inferred_automatically: RNAi_primary
      WBRNAi00040350 Inferred_automatically: RNAi_primary
      WBRNAi00010619 Inferred_automatically: RNAi_primary
      WBRNAi00028806 Inferred_automatically: RNAi_primary
      WBRNAi00115577 Inferred_automatically: RNAi_primary
      WBRNAi00115502 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram759
      Expr5242
      Expr1028068
      Expr1033235
      Expr1144416
      Expr2012219
      Expr2030455
    Drives_construct: WBCnstr00003154
      WBCnstr00033683
    Construct_product: WBCnstr00033683
    Microarray_results (17)
    Expression_cluster (260)
    Interaction: WBInteraction000114668
      WBInteraction000155203
      WBInteraction000519745
      WBInteraction000542764
      WBInteraction000552146
  Map_info: Map: X Position: 1.42294
    Positive: Positive_clone: C11E4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00032037
    WBPaper00038491
    WBPaper00039791
    WBPaper00042257
    WBPaper00042271
    WBPaper00045706
    WBPaper00055090
    WBPaper00061220
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene