WormBase Tree Display for Gene: WBGene00006789

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WBGene00006789	SMap	S_parent	Sequence	CHROMOSOME_I
	Identity	Version	1
		Name	CGC_name	unc-54	Person_evidence	WBPerson261
			Sequence_name	F11C3.3
			Molecular_name	F11C3.3
				F11C3.3.1
				CE09349
			Other_name	myo-4
				CELE_F11C3.3	Accession_evidence	NDB	BX284601
			Public_name	unc-54
		DB_info	Database	AceView	gene	1P454
				WormQTL	gene	WBGene00006789
				WormFlux	gene	WBGene00006789
				NDB	locus_tag	CELE_F11C3.3
				Panther	gene	CAEEL\|WormBase=WBGene00006789\|UniProtKB=P02566
					family	PTHR45615
				NCBI	gene	259839
				RefSeq	protein	NM_061195.7
				SwissProt	UniProtAcc	P02566
				UniProt_GCRP	UniProtAcc	P02566
				OMIM	gene	160710
						160720
						160740
						160741
						160760
		Species	Caenorhabditis elegans
		History	Version_change	1	07 Apr 2004 11:29:42	WBPerson1971	Event	Imported	Initial conversion from geneace
		Status	Live
	Gene_info	Biotype	SO:0001217
		Gene_class	unc
		Allele	WBVar00146729	Inferred_automatically (15)
			WBVar00143679	Inferred_automatically	From strain object: CB1008
			WBVar00143680	Inferred_automatically	From strain object: CB1009
			WBVar00143749	Inferred_automatically	From strain object: CB1108
			WBVar00143785	Inferred_automatically	From strain object: CB1157
			WBVar00143794	Inferred_automatically	From strain object: CB1168
			WBVar00143826	Inferred_automatically	From strain object: CB1201
			WBVar00143867	Inferred_automatically	From strain object: CB1258
					From strain object: CB3019
					From strain object: CB3035
					From strain object: DR119
					From strain object: DR120
					From strain object: DR177
					From strain object: DR404
			WBVar00143901	Inferred_automatically	From strain object: CB1301
					From strain object: RW1029
			WBVar00143913	Inferred_automatically	From strain object: CB1315
					From strain object: CB2221
			WBVar00143306	Inferred_automatically	From strain object: CB569
			WBVar00143311	Inferred_automatically	From strain object: CB576
			WBVar00143372	Inferred_automatically	From strain object: CB651
			WBVar00143532	Inferred_automatically	From strain object: CB843
			WBVar00088545	Inferred_automatically	From strain object: DR226
					From strain object: DR290
					From strain object: DR36
			WBVar00088540	Inferred_automatically	From strain object: DR31
			WBVar00088541	Inferred_automatically	From strain object: DR32
			WBVar00088542	Inferred_automatically	From strain object: DR33
			WBVar00088543	Inferred_automatically	From strain object: DR34
			WBVar00088546	Inferred_automatically	From strain object: DR37
			WBVar00248720	Inferred_automatically	From strain object: RW134
			WBVar00248721	Inferred_automatically	From strain object: RW135
			WBVar00144200
			WBVar00144232
			WBVar00144193
			WBVar00144182
			WBVar02148950
			WBVar00144165
			WBVar00144217
			WBVar00144183
			WBVar00144184
			WBVar00144191
			WBVar00144205
			WBVar00144152
			WBVar02147274
			WBVar00144245
			WBVar00144100
			WBVar00144166
			WBVar00144246
			WBVar00144176
			WBVar00144153
			WBVar00144216
			WBVar00144244
			WBVar00144187
			WBVar00144212
			WBVar00144228
			WBVar00144175
			WBVar00144237
			WBVar00241319
			WBVar00144247
			WBVar00143941
			WBVar00144195
			WBVar00089763
			WBVar00144159
			WBVar00143844
			WBVar00144202
			WBVar00144240
			WBVar00144155
			WBVar00144169
			WBVar00144190
			WBVar00144171
			WBVar00144170
			WBVar00144196
			WBVar00144098
			WBVar00143685
			WBVar02148956
			WBVar00144161
			WBVar00144188
			WBVar00144227
			WBVar00144180
			WBVar00089426
			WBVar00144162
			WBVar00144210
			WBVar00144206
			WBVar00144204
			WBVar00144230
			WBVar00143841
			WBVar00241699
			WBVar00144220
			WBVar00144181
			WBVar00144177
			WBVar00144197
			WBVar00143880
			WBVar00143782
			WBVar00144218
			WBVar00144211
			WBVar00144168
			WBVar00144201
			WBVar00241698
			WBVar00241389
			WBVar00089536
			WBVar00144158
			WBVar00089427
			WBVar00144163
			WBVar00144224
			WBVar00241836
			WBVar00241835
			WBVar00144172
			WBVar00144099
			WBVar00144219
			WBVar00144194
			WBVar00144154
			WBVar00241700
			WBVar00144239
			WBVar00144160
			WBVar00143881
			WBVar00601258
			WBVar00144221
			WBVar00144078
			WBVar00144225
			WBVar00144156
			WBVar00241303
			WBVar00144186
			WBVar00144235
			WBVar00144213
			WBVar00144192
			WBVar00144223
			WBVar00144233
			WBVar00144238
			WBVar00144229
			WBVar00144226
			WBVar00241701
			WBVar00253107
			WBVar00089486
			WBVar00144241
			WBVar00144236
			WBVar00144234
			WBVar00089425
			WBVar00144179
			WBVar00144207
			WBVar00144222
			WBVar00241306
			WBVar00253116
			WBVar00144208
			WBVar00144214
			WBVar00144215
			WBVar00144203
			WBVar00143910
			WBVar00144199
			WBVar00144178
			WBVar00144173
			WBVar00144174
			WBVar00144243
			WBVar00144157
			WBVar00144189
			WBVar00144231
			WBVar00144185
			WBVar00241458
			WBVar00241376
			WBVar00241302
			WBVar00144167
			WBVar00144209
			WBVar00143866
			WBVar00144242
			WBVar00241381
			WBVar00144164
			WBVar00694468
			WBVar00241340
			WBVar00694469
			WBVar00241341
			WBVar00241342
			WBVar00694470
			WBVar00353406
			WBVar00694471
			WBVar00241344
			WBVar00353407
			WBVar00241345
			WBVar00353408
			WBVar00694472
			WBVar00353409
			WBVar00694473
			WBVar00241346
			WBVar00353410
			WBVar01820994
			WBVar00241350
			WBVar00694474
			WBVar00353411
			WBVar00142062
			WBVar00241351
			WBVar00694475
			WBVar00241352
			WBVar00694476
			WBVar00353412
			WBVar00241353
			WBVar00353413
			WBVar00694477
			WBVar00241354
			WBVar00694478
			WBVar00353414
			WBVar00353415
			WBVar00241355
			WBVar00694479
			WBVar00694480
			WBVar00353416
			WBVar00241356
			WBVar00301661
			WBVar00694481
			WBVar00353417
			WBVar00241357
			WBVar00301662
			WBVar00143584
			WBVar00353418
			WBVar00241358
			WBVar00309682
			WBVar00694482
			WBVar00694483
			WBVar00241359
			WBVar00353419
			WBVar00309683
			WBVar00353420
			WBVar00694484
			WBVar00241360
			WBVar00353421
			WBVar00241361
			WBVar00694485
			WBVar00241362
			WBVar00694486
			WBVar00353422
			WBVar00353423
			WBVar00694487
			WBVar00694488
			WBVar00694489
			WBVar00241366
			WBVar00694490
			WBVar00241367
			WBVar00241368
			WBVar00694491
			WBVar00694492
			WBVar01499908
			WBVar00241369
			WBVar00694493
			WBVar00241370
			WBVar00241371
			WBVar00694494
			WBVar01574565
			WBVar00694495
			WBVar00241372
			WBVar00241373
			WBVar00694496
			WBVar00241374
			WBVar00694497
			WBVar00241375
			WBVar00694498
			WBVar00694499
			WBVar00694500
			WBVar00694501
			WBVar00694502
			WBVar00694503
			WBVar00694504
			WBVar00319656
			WBVar00694505
			WBVar00694506
			WBVar01499739
			WBVar00694507
			WBVar00543311
			WBVar00143734
			WBVar00263554
			WBVar00543312
			WBVar00244514
			WBVar00543313
			WBVar00543314
			WBVar00244515
			WBVar00543315
			WBVar00543316
			WBVar00143755
			WBVar00143781
			WBVar02129135
			WBVar02129136
			WBVar00143836
			WBVar01231903
			WBVar01231904
			WBVar01231905
			WBVar01231906
			WBVar00305054
			WBVar00305055
			WBVar00305056
			WBVar00162617
			WBVar00162618
			WBVar00162619
			WBVar00162620
			WBVar00162621
			WBVar00317788
			WBVar00162622
			WBVar00308691
			WBVar00143900
			WBVar00162623
			WBVar00308692
			WBVar00143024
			WBVar01236496
			WBVar00143923
			WBVar01290614
			WBVar01290619
			WBVar01499066
			WBVar01502754
			WBVar01502755
			WBVar01499627
			WBVar01499628
			WBVar01499999
			WBVar00264733
			WBVar01499823
			WBVar00321487
			WBVar00248718
			WBVar00248719
			WBVar00143993
			WBVar00143994
			WBVar00241697
			WBVar00241711
			WBVar00694427
			WBVar00694428
			WBVar00694429
			WBVar00694430
			WBVar00694431
			WBVar00694432
			WBVar00694433
			WBVar01499298
			WBVar00694434
			WBVar00694435
			WBVar00694436
			WBVar00241798
			WBVar00694437
			WBVar00241307
			WBVar00694438
			WBVar00241309
			WBVar00694439
			WBVar01641496
			WBVar00694440
			WBVar00241310
			WBVar00694441
			WBVar00241311
			WBVar00303043
			WBVar00241312
			WBVar00694442
			WBVar00694443
			WBVar00241313
			WBVar01498939
			WBVar00303044
			WBVar00694444
			WBVar00241314
			WBVar00694445
			WBVar00241315
			WBVar00241316
			WBVar00694446
			WBVar00241317
			WBVar00694447
			WBVar00241318
			WBVar00694448
			WBVar00310872
			WBVar00241320
			WBVar00694449
			WBVar00310873
			WBVar00241321
			WBVar00694450
			WBVar00241322
			WBVar00694451
			WBVar00241323
			WBVar00694452
			WBVar00694453
			WBVar00241324
			WBVar00144198
			WBVar00241325
			WBVar00694454
			WBVar00241326
			WBVar00694455
			WBVar00694456
			WBVar00241327
			WBVar00241328
			WBVar00694457
			WBVar00694458
			WBVar00694459
			WBVar00694460
			WBVar00694461
			WBVar00306238
			WBVar00143395
			WBVar00694462
			WBVar00241334
			WBVar00306239
			WBVar00694463
			WBVar00241335
			WBVar00241336
			WBVar00694464
			WBVar00241337
			WBVar00694465
			WBVar00241338
			WBVar00694466
			WBVar00241339
			WBVar00694467
		Legacy_information	Structural gene for major body wall myosin heavy chain. Reference null allele e190 : limp paralysed phenotype at all stages larvae can move slightly more than adults Egl; muscle ultrastructure very disorganized few thick filaments. ES3 ME0. NA (recessive) > 50 including e1108amber; e1301ts; e675sd and s291 (in frame internal deletion mutants with heavy chain fragment behavioral phenotype almost paralysed slight twitcher); also Tc1 insertion mutants; etc. Also unusual suppressor alleles (NA > 15) e.g. s74 : dominant suppressor of unc-22(s12) no other dominant phenotype recessive phenotype slow stiff normal muscle ultrastructure; alteration in S1 portion of protein. Also Class 3 (dominant) alleles reference allele e1152sd : severe rigid paralysis small; e1152/+ paralysed weaker phenotype. ES3 ME0. NA (dominant) > 10 : e1153 n489 etc.; resemble e1152 or more severe recessive lethal. Intragenic revertants have Class 1 phenotypes.
			See unc-54.
			See also e569, e576, e651, e675, e843, e903, e1008, e1009, e1021, e1092, e1108, e1115, e1152, e1153, e1157, e1168, e1201, e1213, e1219, e1223, e1257, e1258, e1273, e1274, e1300, e1301, e1311, e1315, e1328, e1360, e1419, e1420, n325, n326, n327, n489, n794, r274, r308, r322, r323, r327, r360, s74, s75, s76, s77, s78, s95, s291, s409, s411
			[C.elegansII] e190 : limp paralysed phenotype at all stages; larvae can move slightly more than adults; Egl; muscle ultrastructure very disorganized few thick filaments. ES3 ME0. OA>50 (recessive): e1108amb,e1301ts, e675sd and s291 (in frame internal deletion mutants, almost paralysed slight twitchers), etc. Also unusual suppressor alleles, OA>15: s74 (dominant suppressor of unc-22(s12), recessive slow, stiff; normal muscle ultrastructure) Also dominant antimorphic alleles, OA>10:e1152sd (severe rigid paralysis, small;e1152/+ paralysed weaker phenotype. ES3 ME0),r344 (recessive lethal, r344/+ severely paralysed), etc. Intragenic revertants have recessive paralysed phenotype. Some recessive alleles (r274, e1420 etc.) are dominant antimorphs in smg background. Cloned: encodes MHC B (MYO-4), major bodywall muscle myosin heavy chain. 6 kb message,1117 aa protein. Extensive molecular analysis. [Epstein et al. 1974; McLachlan and Karn 1982;Dibb et al. 1989; Bejsovec and Anderson 1990; TR; RW]
		Strain (1380)
		RNASeq_FPKM (74)
		GO_annotation (31)
		Ortholog	WBGene00060889	Caenorhabditis remanei	From_analysis	OMA
						TreeFam
						Inparanoid_8
						WormBase-Compara
			WBGene00023596	Caenorhabditis briggsae	From_analysis	OrthoMCL
			WBGene00025170	Caenorhabditis briggsae	From_analysis	OrthoMCL
			WBGene00030079	Caenorhabditis briggsae	From_analysis	OrthoMCL
			WBGene00032487	Caenorhabditis briggsae	From_analysis	OrthoMCL
			WBGene00035391	Caenorhabditis briggsae	From_analysis	OrthoMCL
			WBGene00038900	Caenorhabditis briggsae	From_analysis	OrthoMCL
						OMA
						Inparanoid_8
						WormBase-Compara
			WBGene00040055	Caenorhabditis briggsae	From_analysis	OrthoMCL
			WBGene00040581	Caenorhabditis briggsae	From_analysis	OrthoMCL
			WBGene00041777	Caenorhabditis briggsae	From_analysis	OrthoMCL
			WBGene00147183	Caenorhabditis brenneri	From_analysis	OMA
						TreeFam
						Inparanoid_8
						WormBase-Compara
			WBGene00117763	Pristionchus pacificus	From_analysis	OMA
						Inparanoid_8
						WormBase-Compara
			WBGene00131142	Caenorhabditis japonica	From_analysis	Inparanoid_8
						WormBase-Compara
			WBGene00223568	Brugia malayi	From_analysis	WormBase-Compara
			WBGene00224377	Brugia malayi	From_analysis	WormBase-Compara
			CBOVI.g9085	Caenorhabditis bovis	From_analysis	WormBase-Compara
			CSP21.g6392	Caenorhabditis parvicauda	From_analysis	WormBase-Compara
			CSP26.g5864	Caenorhabditis zanzibari	From_analysis	WormBase-Compara
			CSP28.g8240	Caenorhabditis panamensis	From_analysis	WormBase-Compara
			CSP29.g4259	Caenorhabditis becei	From_analysis	WormBase-Compara
			CSP31.g22272	Caenorhabditis uteleia	From_analysis	WormBase-Compara
			CSP32.g9281	Caenorhabditis sulstoni	From_analysis	WormBase-Compara
			CSP38.g14410	Caenorhabditis quiockensis	From_analysis	WormBase-Compara
			CSP39.g1808	Caenorhabditis waitukubuli	From_analysis	WormBase-Compara
			CSP40.g12497	Caenorhabditis tribulationis	From_analysis	WormBase-Compara
			Cang_2012_03_13_15248.g24974	Caenorhabditis angaria	From_analysis	WormBase-Compara
			Cnig_chr_I.g3807	Caenorhabditis nigoni	From_analysis	WormBase-Compara
			Csp11.Scaffold572.g4325	Caenorhabditis tropicalis	From_analysis	WormBase-Compara
			Csp5_scaffold_01801.g23223	Caenorhabditis sinica	From_analysis	WormBase-Compara
			Csp5_scaffold_06941.g37197	Caenorhabditis sinica	From_analysis	WormBase-Compara
			FL83_09136	Caenorhabditis latens	From_analysis	WormBase-Compara
			GCK72_001454	Caenorhabditis remanei	From_analysis	WormBase-Compara
			OTIPU.nOt.2.0.1.g02608	Oscheius tipulae	From_analysis	WormBase-Compara
			Pan_g2033	Panagrellus redivivus	From_analysis	WormBase-Compara
			Sp34_10010600	Caenorhabditis inopinata	From_analysis	WormBase-Compara
			chrI_pilon.g2982	Caenorhabditis elegans	From_analysis	WormBase-Compara
			WBGene00242128	Onchocerca volvulus	From_analysis	WormBase-Compara
			WBGene00246956	Onchocerca volvulus	From_analysis	WormBase-Compara
			WBGene00266272	Strongyloides ratti	From_analysis	WormBase-Compara
			WBGene00292203	Trichuris muris	From_analysis	WormBase-Compara
			SGD:S000001065	Saccharomyces cerevisiae	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OrthoInspector
						Panther
						SonicParanoid
			FB:FBgn0264695	Drosophila melanogaster	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-991123-5	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-000322-5	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-020604-1	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-030131-271	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-030131-6206	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-031112-1	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-090311-5	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-061027-393	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-070705-73	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-081124-1	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-070705-74	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-070822-12	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-060531-50	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-100914-2	Danio rerio	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:7567	Homo sapiens	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:7572	Homo sapiens	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:7573	Homo sapiens	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:7574	Homo sapiens	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:7576	Homo sapiens	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:7577	Homo sapiens	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:7578	Homo sapiens	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:7571	Homo sapiens	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:31073	Homo sapiens	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:15906	Homo sapiens	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:1339711	Mus musculus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:1339710	Mus musculus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:1339709	Mus musculus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:1339713	Mus musculus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:1339712	Mus musculus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:97255	Mus musculus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:2155600	Mus musculus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:1339967	Mus musculus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:3643515	Mus musculus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:3710243	Mus musculus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			RGD:3138	Rattus norvegicus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			RGD:62029	Rattus norvegicus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			RGD:62030	Rattus norvegicus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			RGD:1565858	Rattus norvegicus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			RGD:1307994	Rattus norvegicus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			RGD:3139	Rattus norvegicus	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
		Paralog (21)
		Structured_description	Concise_description	unc-54 encodes a muscle myosin class II heavy chain (MHC B); UNC-54 is the major myosin heavy chain expressed in C. elegans and is required for locomotion and egg-laying; in vivo and in vitro, UNC-54 interacts with ITR-1, an IP3 receptor, and this interaction may provide a link between calcium signaling and the muscle cytoskeleton; UNC-54 is a thick filament component that is expressed in multiple muscle cell classes including body wall, intestinal, anal depressor, and sphincter muscles as well as sex-specific muscles that develop postembryonically.	Paper_evidence	WBPaper00000232
						WBPaper00000647
						WBPaper00001014
						WBPaper00005299
						WBPaper00005940
					Curator_confirmed	WBPerson1843
					Date_last_updated	17 Jun 2004 00:00:00
			Automated_description	Enables actin filament binding activity and microfilament motor activity. A structural constituent of muscle. Involved in several processes, including egg-laying behavior; muscle contraction; and skeletal muscle myosin thick filament assembly. Located in A band and striated muscle myosin thick filament. Part of muscle myosin complex. Expressed in anal depressor muscle; body wall musculature; head; vulval muscle; and in male. Human ortholog(s) of this gene implicated in several diseases, including congenital heart disease (multiple); distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3).	Paper_evidence	WBPaper00065943
					Curator_confirmed	WBPerson324
						WBPerson37462
					Inferred_automatically	This description was generated automatically by a script based on data from the WS291 version of WormBase
					Date_last_updated	29 Nov 2023 00:00:00
	Disease_info	Potential_model (30)
	Molecular_info	Corresponding_CDS	F11C3.3
		Corresponding_transcript	F11C3.3.1
		Other_sequence (386)
		Associated_feature (32)
	Experimental_info	RNAi_result (12)
		Expr_pattern (15)
		Drives_construct (151)
		Construct_product	WBCnstr00011688
			WBCnstr00011704
			WBCnstr00013869
			WBCnstr00015881
			WBCnstr00018819
			WBCnstr00034149
		Antibody (11)
		Microarray_results (22)
		Expression_cluster (308)
		Interaction (231)
		WBProcess	WBbiopr:00000040
	Map_info	Map	I	Position	27.9607	Error	0.002243
		Well_ordered
		Positive	Inside_rearr	eDf3
				eDf10
				dxDf2
			Positive_clone	F11C3	Inferred_automatically	From sequence, transcript, pseudogene data
				SG25/36
		Mapping_data	2_point (22)
			Multi_point (47)
			Pos_neg_data (20)
		Landmark_gene
	Reference (599)
	Remark	unc-54 posneg pcr data gives map conflict, spans deletion breakpoint ? jah 8.97
	Method	Gene