WormBase Tree Display for Gene: WBGene00004810

WBGene00004810 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: Y60A3A
  Identity: Version: 1
    Name: CGC_name: skr-4 Person_evidence: WBPerson322
      Sequence_name: Y60A3A.18
      Molecular_name: Y60A3A.18
        Y60A3A.18.1
        CE24523
      Other_name: CELE_Y60A3A.18 Accession_evidence: NDB BX284605
      Public_name: skr-4
    DB_info: Database: AceView gene 5U393
        WormQTL gene WBGene00004810
        WormFlux gene WBGene00004810
        NDB locus_tag CELE_Y60A3A.18
        Panther gene CAEEL|WormBase=WBGene00004810|UniProtKB=Q9U1Y9
          family PTHR11165
        NCBI gene 191762
        RefSeq protein NM_075456.7
        TREEFAM TREEFAM_ID TF354233
        TrEMBL UniProtAcc Q9U1Y9
        UniProt_GCRP UniProtAcc Q9U1Y9
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: skr
    Allele (56)
    RNASeq_FPKM (74)
    GO_annotation: 00098536
      00098537
      00098538
      00098539
      00098540
      00113217
    Ortholog (64)
    Paralog (19)
    Structured_description: Concise_description: The skr-4 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-4(RNAi) animals are at least superficially normal. Paper_evidence: WBPaper00005128
            WBPaper00005129
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in intestine. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y60A3A.18
    Corresponding_transcript: Y60A3A.18.1
    Associated_feature: WBsf1003388
      WBsf1021843
  Experimental_info: RNAi_result: WBRNAi00069084 Inferred_automatically: RNAi_primary
      WBRNAi00086783 Inferred_automatically: RNAi_primary
      WBRNAi00057808 Inferred_automatically: RNAi_primary
      WBRNAi00086782 Inferred_automatically: RNAi_primary
      WBRNAi00086801 Inferred_automatically: RNAi_primary
      WBRNAi00069085 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2440
      Expr1161240
      Expr2015852
      Expr2034085
    Drives_construct: WBCnstr00010831
    Construct_product: WBCnstr00010831
    Microarray_results (15)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00033444:BacteriaDiet_regulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037950:intestine_larva_enriched
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038168:lin-35_upregulated
      WBPaper00040990:PA14_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044128:daf-2(e1370)_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045257:bar-1(ga80)_upregulated
      WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
      WBPaper00045316:prg-1_upregulated_L1
      WBPaper00045401:N.parisii_8h_upregulated
      WBPaper00045401:N.parisii_30h_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00046337:monosomal_N2_vs_daf-2_downregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046858:elt-2(RNAi)_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048690:hermaphrodite-Z1-Z4_enriched
      WBPaper00048952:glucose_repressed
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048988:neuron_expressed
      WBPaper00049098:heat-induced_hrde-1(tm1200)
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049368:daf-2(e1370)_upregulated
      WBPaper00049484:elt-2(RNAi)_upregulated_L4
      WBPaper00049498:npr-1(ur89)_regulated_7
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050121:mir-60(n4947)_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050448:KGB-1-induced
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051137:N.parisii-virus_upregulated_N2
      WBPaper00051137:Orsay-virus_upregulated_N2
      WBPaper00051137:Orsay-virus_upregulated_rde-1(ne219)
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:intestine_specific
      WBPaper00051265:F4_hrde-1(tm1200)_downregulated
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00051305:vit-2(ac3)_upregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:OrsayVirus-infection_upregulated
      WBPaper00053020:OrsayVirus-infection_upregulated_microarray
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:stavudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053664:ins-11(tm1053)_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053909:N2_vs_CB4856_upregulated
      WBPaper00054192:cold-shock_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00056868:P.aeruginosa_upregulated_smallRNA
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057158:mdt-15(tm2182)_dependent_15C_downregulated
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00058948:npr-8(ok1439)_upregulated_PA14
      WBPaper00058948:PA14_downregulated
      WBPaper00059373:stt-3(RNAi)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060871:M.humicola-extract_4h_regulated
      WBPaper00060886:spr-5(by101);met-2(n4256)_upregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061319:pnp-1(jy90)_upregulated
      WBPaper00061319:pnp-1(jy121)_upregulated
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061422:let-607(RNAi)_regulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:W01F3.2_1554-Y106G6D.8
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061823:mex-3(spr9)_downregulated
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00061952:daf-18(nr2037)_downregulated
      WBPaper00061952:daf-18(yh1)_downregulated
      WBPaper00061995:mter-4(syb3662syb3403)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062184:PA14_upregulated
      WBPaper00062193:daf-16(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064225:heat-shock_upregulated_protein
      WBPaper00064494:postdauer_downregulated_AWA
      WBPaper00064532:pals-22(jy3)_upregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064532:pals-25(jy111)_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065029:cadmium_upregulated
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:JU1400_N.ironsii_regulated
      WBPaper00065086:JU1400_N.parisii_regulated
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065086:N2_N.ferruginous_regulated
      WBPaper00065086:N2_N.ironsii_regulated
      WBPaper00065086:N2_N.parisii_regulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065841:3_4
      WBPaper00065841:3_5
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4386_cluster_1_2
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00031850:mdt-15(RNAi)_upregulated
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00034739:N2moreDR1350
      WBPaper00034739:RIL17lessRIL14
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035227:heat_shock_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_I
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00037695:DD_3-day
      WBPaper00038060:SUMO-1_downregulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038231:Cry5B_2-fold_upregulated
      WBPaper00038304:octr-1_regulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.5
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040876:mir-35_upregulated
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045401:N.parisii_34h_upregulated_N2
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00053550:daf-19(m86)_downregulated_L1
      WBPaper00056330:mrps-5(RNAi)_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction: WBInteraction000543612
      WBInteraction000549972
      WBInteraction000549998
      WBInteraction000550271
      WBInteraction000567847
      WBInteraction000576559
      WBInteraction000580394
      WBInteraction000583600
  Map_info: Map: V Position: 23.9984 Error: 0.009899
    Positive: Positive_clone: Y60A3A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00059442
    WBPaper00061319
    WBPaper00062289
    WBPaper00062345
    WBPaper00065331
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene