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WormBase Tree Display for Gene: WBGene00004459

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Name Class

WBGene00004459EvidenceCGC_data_submission
SMapS_parentSequenceC23G10
IdentityVersion1
NameCGC_namerpn-2Person_evidenceWBPerson1551
Sequence_nameC23G10.4
Molecular_nameC23G10.4a
C23G10.4a.1
CE40437
C23G10.4b
CE31311
C23G10.4b.1
Other_nameCELE_C23G10.4Accession_evidenceNDBBX284603
Public_namerpn-2
DB_infoDatabaseAceViewgene3H291
WormQTLgeneWBGene00004459
WormFluxgeneWBGene00004459
NDBlocus_tagCELE_C23G10.4
PanthergeneCAEEL|WormBase=WBGene00004459|UniProtKB=Q18115
familyPTHR10943
NCBIgene175877
RefSeqproteinNM_065945.7
NM_001392118.1
SwissProtUniProtAccQ18115
TREEFAMTREEFAM_IDTF105742
UniProt_GCRPUniProtAccQ18115
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrpn
Allele (43)
StrainWBStrain00001248
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (47)
ParalogWBGene00004458Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionrpn-2 encodes a non-ATPase subunit of the 26S proteasome's 19S regulatory paritcle (RP) base subcomplex; RPN-2 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding and recognition of protein substrates and/or recycling of ubiquitin moieties during protein degradation; RPN-2 is expressed sporadically at all stages of development in the pharynx, intestine, body wall muscle, somatic gonad, neurons, and hypodermis.Paper_evidenceWBPaper00004403
WBPaper00005553
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables protein kinase C binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in several cellular components, including cell cortex; mitotic spindle; and nuclear membrane. Expressed in intestine. Is an ortholog of human PSMD1 (proteasome 26S subunit, non-ATPase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC23G10.4a
C23G10.4b
Corresponding_CDS_historyC23G10.4a:wp165
Corresponding_transcriptC23G10.4a.1
C23G10.4b.1
Other_sequence (83)
Associated_featureWBsf645250
WBsf645251
WBsf659035
WBsf225069
WBsf225070
Experimental_infoRNAi_result (63)
Expr_patternChronogram2025
Expr2103
Expr5315
Expr8131
Expr1024979
Expr1032262
Expr1145053
Expr2015490
Expr2033725
Drives_constructWBCnstr00002141
WBCnstr00008740
WBCnstr00035469
Construct_productWBCnstr00035469
AntibodyWBAntibody00001423
WBAntibody00001424
WBAntibody00001425
Microarray_results (38)
Expression_cluster (160)
Interaction (208)
Map_infoMapIIIPosition-1.40919Error0.000212
PositivePositive_cloneC23G10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (12)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene