WormBase Tree Display for Gene: WBGene00004459

WBGene00004459 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: C23G10
  Identity: Version: 1
    Name: CGC_name: rpn-2 Person_evidence: WBPerson1551
      Sequence_name: C23G10.4
      Molecular_name: C23G10.4a
        C23G10.4a.1
        CE40437
        C23G10.4b
        CE31311
        C23G10.4b.1
      Other_name: CELE_C23G10.4 Accession_evidence: NDB BX284603
      Public_name: rpn-2
    DB_info: Database: AceView gene 3H291
        WormQTL gene WBGene00004459
        WormFlux gene WBGene00004459
        NDB locus_tag CELE_C23G10.4
        Panther gene CAEEL|WormBase=WBGene00004459|UniProtKB=Q18115
          family PTHR10943
        NCBI gene 175877
        RefSeq protein NM_065945.7
            NM_001392118.1
        SwissProt UniProtAcc Q18115
        TREEFAM TREEFAM_ID TF105742
        UniProt_GCRP UniProtAcc Q18115
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rpn
    Allele (43)
    Strain: WBStrain00001248
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (47)
    Paralog: WBGene00004458 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: rpn-2 encodes a non-ATPase subunit of the 26S proteasome's 19S regulatory paritcle (RP) base subcomplex; RPN-2 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding and recognition of protein substrates and/or recycling of ubiquitin moieties during protein degradation; RPN-2 is expressed sporadically at all stages of development in the pharynx, intestine, body wall muscle, somatic gonad, neurons, and hypodermis. Paper_evidence: WBPaper00004403
            WBPaper00005553
            WBPaper00005654
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables protein kinase C binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in several cellular components, including cell cortex; mitotic spindle; and nuclear membrane. Expressed in intestine. Is an ortholog of human PSMD1 (proteasome 26S subunit, non-ATPase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C23G10.4a
      C23G10.4b
    Corresponding_CDS_history: C23G10.4a:wp165
    Corresponding_transcript: C23G10.4a.1
      C23G10.4b.1
    Other_sequence (83)
    Associated_feature: WBsf645250
      WBsf645251
      WBsf659035
      WBsf225069
      WBsf225070
  Experimental_info: RNAi_result: WBRNAi00096272 Inferred_automatically: RNAi_primary
      WBRNAi00095966 Inferred_automatically: RNAi_primary
      WBRNAi00089328 Inferred_automatically: RNAi_primary
      WBRNAi00089428 Inferred_automatically: RNAi_primary
      WBRNAi00089449 Inferred_automatically: RNAi_primary
      WBRNAi00114684 Inferred_automatically: RNAi_primary
      WBRNAi00095889 Inferred_automatically: RNAi_primary
      WBRNAi00096701 Inferred_automatically: RNAi_primary
      WBRNAi00096716 Inferred_automatically: RNAi_primary
      WBRNAi00089445 Inferred_automatically: RNAi_primary
      WBRNAi00096795 Inferred_automatically: RNAi_primary
      WBRNAi00022811 Inferred_automatically: RNAi_primary
      WBRNAi00096450 Inferred_automatically: RNAi_primary
      WBRNAi00114682 Inferred_automatically: RNAi_primary
      WBRNAi00096705 Inferred_automatically: RNAi_primary
      WBRNAi00096118 Inferred_automatically: RNAi_primary
      WBRNAi00096703 Inferred_automatically: RNAi_primary
      WBRNAi00096718 Inferred_automatically: RNAi_primary
      WBRNAi00080757 Inferred_automatically: RNAi_primary
      WBRNAi00096697 Inferred_automatically: RNAi_primary
      WBRNAi00093508 Inferred_automatically: RNAi_primary
      WBRNAi00112147 Inferred_automatically: RNAi_primary
      WBRNAi00114683 Inferred_automatically: RNAi_primary
      WBRNAi00064396 Inferred_automatically: RNAi_primary
      WBRNAi00089489 Inferred_automatically: RNAi_primary
      WBRNAi00096041 Inferred_automatically: RNAi_primary
      WBRNAi00112248 Inferred_automatically: RNAi_primary
      WBRNAi00089375 Inferred_automatically: RNAi_primary
      WBRNAi00096720 Inferred_automatically: RNAi_primary
      WBRNAi00089423 Inferred_automatically: RNAi_primary
      WBRNAi00080745 Inferred_automatically: RNAi_primary
      WBRNAi00089443 Inferred_automatically: RNAi_primary
      WBRNAi00033568 Inferred_automatically: RNAi_primary
      WBRNAi00002555 Inferred_automatically: RNAi_primary
      WBRNAi00089436 Inferred_automatically: RNAi_primary
      WBRNAi00089448 Inferred_automatically: RNAi_primary
      WBRNAi00041009 Inferred_automatically: RNAi_primary
      WBRNAi00008426 Inferred_automatically: RNAi_primary
      WBRNAi00112247 Inferred_automatically: RNAi_primary
      WBRNAi00089495 Inferred_automatically: RNAi_primary
      WBRNAi00085473 Inferred_automatically: RNAi_primary
      WBRNAi00096632 Inferred_automatically: RNAi_primary
      WBRNAi00108312 Inferred_automatically: RNAi_primary
      WBRNAi00024598 Inferred_automatically: RNAi_primary
      WBRNAi00078742 Inferred_automatically: RNAi_primary
      WBRNAi00096699 Inferred_automatically: RNAi_primary
      WBRNAi00078708 Inferred_automatically: RNAi_primary
      WBRNAi00096195 Inferred_automatically: RNAi_primary
      WBRNAi00096367 Inferred_automatically: RNAi_primary
      WBRNAi00089493 Inferred_automatically: RNAi_primary
      WBRNAi00089447 Inferred_automatically: RNAi_primary
      WBRNAi00096533 Inferred_automatically: RNAi_primary
      WBRNAi00095502 Inferred_automatically: RNAi_primary
      WBRNAi00089496 Inferred_automatically: RNAi_primary
      WBRNAi00093513 Inferred_automatically: RNAi_primary
      WBRNAi00002795 Inferred_automatically: RNAi_primary
      WBRNAi00089456 Inferred_automatically: RNAi_primary
      WBRNAi00041010 Inferred_automatically: RNAi_primary
      WBRNAi00114685 Inferred_automatically: RNAi_primary
      WBRNAi00111715 Inferred_automatically: RNAi_primary
      WBRNAi00089484 Inferred_automatically: RNAi_primary
      WBRNAi00089432 Inferred_automatically: RNAi_primary
      WBRNAi00089441 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram2025
      Expr2103
      Expr5315
      Expr8131
      Expr1024979
      Expr1032262
      Expr1145053
      Expr2015490
      Expr2033725
    Drives_construct: WBCnstr00002141
      WBCnstr00008740
      WBCnstr00035469
    Construct_product: WBCnstr00035469
    Antibody: WBAntibody00001423
      WBAntibody00001424
      WBAntibody00001425
    Microarray_results (38)
    Expression_cluster (160)
    Interaction (208)
  Map_info: Map: III Position: -1.40919 Error: 0.000212
    Positive: Positive_clone: C23G10 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (12)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene