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WormBase Tree Display for Gene: WBGene00004459

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Name Class

WBGene00004459EvidenceCGC_data_submission
SMapS_parentSequenceC23G10
IdentityVersion1
NameCGC_namerpn-2Person_evidenceWBPerson1551
Sequence_nameC23G10.4
Molecular_nameC23G10.4a
C23G10.4a.1
CE40437
C23G10.4b
CE31311
C23G10.4b.1
Other_nameCELE_C23G10.4Accession_evidenceNDBBX284603
Public_namerpn-2
DB_infoDatabaseAceViewgene3H291
WormQTLgeneWBGene00004459
WormFluxgeneWBGene00004459
NDBlocus_tagCELE_C23G10.4
PanthergeneCAEEL|WormBase=WBGene00004459|UniProtKB=Q18115
familyPTHR10943
NCBIgene175877
RefSeqproteinNM_065945.7
NM_001392118.1
SwissProtUniProtAccQ18115
TREEFAMTREEFAM_IDTF105742
UniProt_GCRPUniProtAccQ18115
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrpn
Allele (43)
StrainWBStrain00001248
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (47)
ParalogWBGene00004458Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionrpn-2 encodes a non-ATPase subunit of the 26S proteasome's 19S regulatory paritcle (RP) base subcomplex; RPN-2 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding and recognition of protein substrates and/or recycling of ubiquitin moieties during protein degradation; RPN-2 is expressed sporadically at all stages of development in the pharynx, intestine, body wall muscle, somatic gonad, neurons, and hypodermis.Paper_evidenceWBPaper00004403
WBPaper00005553
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables protein kinase C binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in several cellular components, including cell cortex; mitotic spindle; and nuclear membrane. Expressed in intestine. Is an ortholog of human PSMD1 (proteasome 26S subunit, non-ATPase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC23G10.4a
C23G10.4b
Corresponding_CDS_historyC23G10.4a:wp165
Corresponding_transcriptC23G10.4a.1
C23G10.4b.1
Other_sequence (83)
Associated_featureWBsf645250
WBsf645251
WBsf659035
WBsf225069
WBsf225070
Experimental_infoRNAi_result (63)
Expr_patternChronogram2025
Expr2103
Expr5315
Expr8131
Expr1024979
Expr1032262
Expr1145053
Expr2015490
Expr2033725
Drives_constructWBCnstr00002141
WBCnstr00008740
WBCnstr00035469
Construct_productWBCnstr00035469
AntibodyWBAntibody00001423
WBAntibody00001424
WBAntibody00001425
Microarray_results (38)
Expression_cluster (160)
Interaction (208)
Map_infoMapIIIPosition-1.40919Error0.000212
PositivePositive_cloneC23G10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00025088
WBPaper00029221
WBPaper00031906
WBPaper00032322
WBPaper00032980
WBPaper00038491
WBPaper00048675
WBPaper00049828
WBPaper00055090
WBPaper00056008
WBPaper00062237
WBPaper00063122
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene