WormBase Tree Display for Gene: WBGene00004398

WBGene00004398 SMap: S_parent: Sequence: ZK1290
  Identity: Version: 1
    Name: CGC_name: rol-8 Person_evidence: WBPerson261
      Sequence_name: ZK1290.3
      Molecular_name: ZK1290.3
        ZK1290.3.1
        CE29156
      Other_name: col6 Accession_evidence: EMBL M25477
        col-6 Paper_evidence: WBPaper00001927
        CELE_ZK1290.3 Accession_evidence: NDB BX284602
      Public_name: rol-8
    DB_info: Database: AceView gene 2H835
        WormQTL gene WBGene00004398
        WormFlux gene WBGene00004398
        NDB locus_tag CELE_ZK1290.3
        Panther gene CAEEL|WormBase=WBGene00004398|UniProtKB=P18831
          family PTHR24637
        NCBI gene 174226
        RefSeq protein NM_063181.7
        SwissProt UniProtAcc P18831
        UniProt_GCRP UniProtAcc P18831
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info (11)
  Molecular_info: Corresponding_CDS: ZK1290.3
    Corresponding_CDS_history: ZK1290.3b:wp274
    Corresponding_transcript: ZK1290.3.1
    Other_sequence (223)
    Associated_feature: WBsf988470
      WBsf988471
      WBsf1012548
      WBsf1012549
      WBsf221608
      WBsf221609
  Experimental_info: RNAi_result (16)
    Expr_pattern: Expr762
      Expr1022612
      Expr1032208
      Expr1162631
      Expr2015405
      Expr2033640
    Drives_construct: WBCnstr00035511
    Construct_product: WBCnstr00035511
    Microarray_results (28)
    Expression_cluster: WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036231:long-telomeres_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_embryo_enriched
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038061:aldicarb_upregulated
      WBPaper00038118:stress_upregulated_N2
      WBPaper00038168:lin-15B(n744)_downregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040209:B.thuringiensis_downregulated_MY15
      WBPaper00042034:NO_upregulated_hsf-1(sy441)
      WBPaper00042194:nhr-114(RNAi)_downregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042477:prp-8(RNAi)_downregulated_RNAseq
      WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00043945:MeHg_upregulated
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044260:nicotinc-acid_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044743:wdr-23_neuron_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00044786:lem-2(tm1582)_upregulated
      WBPaper00045217:prg-1_progressively_regulated
      WBPaper00045316:prg-1_downregulated_L1
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045934:wrn-1(gk99)_downregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_downregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_upregulated
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046499:AMPK_regulated
      WBPaper00046805:csr-1(RNAi)_downregulated_Set1
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00049018:swsn-2.2(RNAi)_downregulated
      WBPaper00049098:hrde-1(tm1200)-induced_23C
      WBPaper00049159:Microwave_upregulated_L4
      WBPaper00049635:dop-1(vs100)_downregulated
      WBPaper00049732:blmp-1(tm548)_vs_N2_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051265:F1_morc-1(tm6048)_upregulated
      WBPaper00051265:F4_hrde-1(tm1200)_downregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053657:JU2519_M.humicola-infection_12hr
      WBPaper00053771:down_by_skn-1(RNAi)_at_24h-NaCl
      WBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88)
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054410:set-9(rw5)_downregulated
      WBPaper00054410:set-26(tm2467)_downregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055013:hmg-4(RNAi)_downregulated
      WBPaper00055013:spt-16(RNAi)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055648:male-vas-deferens_expressed
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056039:ptrn-1(tm5597)_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056169:rrf-3(pk1426)_downregulated_adult
      WBPaper00056169:rrf-3(pk1426)_downregulated_L3
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056169:rrf-3(pk1426)_upregulated_L2
      WBPaper00056218:daf-16(mu86)_downregulated_Day7
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056290:mdt-15(mg584)_upregulated
      WBPaper00056330:glycine_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057347:nhr-14(tm1473)_downreglated
      WBPaper00058598:mex-1(or286)_downregulated
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058678:DAF-12_downregulated_PVD
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00058969:RIS_depleted
      WBPaper00059231:alh-6(lax105)_L4_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059378:cec-4(ok3124);lmn-1(Y59C)_vs_lmn-1(Y59C)_upregulated
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059426:SiO2-nanoparticles_upregulated
      WBPaper00059477:hlh-2(RNAi)_regulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059739:hira-1(gk835598)_downregulated_L1
      WBPaper00059739:hira-1(gk835598)_downregulated_L4
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060273:vrk-1(RNAi)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060445:ikb-1(nr2027)_downregulated_L4
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060526:plp-1(ok2155)_upregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060744:Radiation_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00060921:cat-2(e1112)_downregulated
      WBPaper00060921:tdc-1(n3419)_downregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:HB115_upregulated
      WBPaper00061007:M.braciatum_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061081:skpo-1(ok1640)_upregulated_OP50
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061340:ADL_parent
      WBPaper00061340:Ciliated_amphid_neuron
      WBPaper00061340:Neuroblast_AFD_RMD
      WBPaper00061340:Neuroblast_ASE_ASJ_AUA
      WBPaper00061340:Neuroblast_BAG_SMDVx
      WBPaper00061340:Neuroblast_IL1_IL2
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:prg-1(tm872)_upregulated
      WBPaper00061527:sqt-2-dpy-9
      WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
      WBPaper00061653:alh-4(hj221)_downregulated
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062056:dpl-1(n2994)_downregulated
      WBPaper00062056:lin-35(n745)_downregulated
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062078:NMR-HspB1_regulated
      WBPaper00062156:jmjd-1.2(zr1010)_upregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062440:crh-1(syb385)_upregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00062534:fat-P-80_downregulated
      WBPaper00062534:fat-P-80_downregulated_ech-6(RNAi)
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064055:trl-1(cas1078)_upregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064122:vulva_transcriptome
      WBPaper00064130:Beta-Amyloid_8h_downregulated_mRNA
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064532:pals-25(icb98)_downregulated
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064661:lpd-3(ok2138)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064762:freezing-thaw_regulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064992:Eugenol_downregulated
      WBPaper00064992:heat-shock_upregulated
      WBPaper00065029:cadmium_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065258:anchor-cell_enriched
      WBPaper00065315:mating_upregulated_Day2-7
      WBPaper00065315:mating_upregulated_Day6-7
      WBPaper00065578:gcn-1(nc40)_upregulated
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065749:Heat-Shock_downregulated_N2
      WBPaper00065841:33_0
      WBPaper00065841:46_0
      WBPaper00065841:82_0
      WBPaper00065877:rege-1(imm070)_downregulated_PA14
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_transcript
      WBPaper00065945:global-rpoa-2(-)_downregulated_transcript
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066004:tdp-1(csb38)_upregulated
      WBPaper00066093:E.coli-purE_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4386_cluster_2_4
      cgc4489_group_19
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00005124:testosterone_10-9M_regulated
      WBPaper00025099:MA_specific
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_E
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032948:FedUp
      WBPaper00032948:MoltOssilate
      WBPaper00033101:spr-5_regulated
      WBPaper00034739:N2lessDR1350
      WBPaper00035227:heat_shock_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00038060:SUMO-1_downregulated
      WBPaper00038172:crh-1null_down_regulated
      WBPaper00038304:octr-1_regulated
      WBPaper00040116:pRJ-FR.5_down_regulated
      WBPaper00040185:nhr-23(RNAi)_downregulated
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040963:Q50_up
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00041207:CE_dauer_down
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042258:DA1877_downregulated_YoungAdult
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045015:nhr-25(RNAi)_downregulated
      WBPaper00045437:Toxic-Se_downregulated
      WBPaper00046083:oga-1(ok1207)_OP50_downregulated
      WBPaper00046083:ogt-1(ok1474)_OP50_downregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00047070:N2_UV_downregulated
      WBPaper00047070:xpa-1_UV_downregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00049311:Ag-MNP_regulated
      WBPaper00049311:sAg-MNP_regulated
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      [cgc6390]:Cluster_A
      [cgc6390]:male_sex-enriched
    Interaction (119)
    WBProcess: WBbiopr:00000124
  Map_info: Map: II Position: 0.504391 Error: 0.000111
    Well_ordered
    Positive: Positive_clone: COL6
        ZK1290 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 1523
        2596
        2597
      Multi_point: 836
        837
        1054
        1243
        4733
        4797
        5523
      Pos_neg_data: 3235
        3236
        3237
        3238
        3239
        3240
        3241
  Reference (36)
  Method: Gene