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WormBase Tree Display for Gene: WBGene00004345

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Name Class

WBGene00004345SMapS_parentSequenceCHROMOSOME_X
IdentityVersion1
NameCGC_namergs-2Person_evidenceWBPerson330
Sequence_nameF16H9.1
Molecular_name (12)
Other_nameCELE_F16H9.1Accession_evidenceNDBBX284606
Public_namergs-2
DB_infoDatabase (10)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrgs
Allele (258)
StrainWBStrain00026362
WBStrain00026360
RNASeq_FPKM (74)
GO_annotation00011399
00047258
Ortholog (47)
ParalogWBGene00004344Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00004346Caenorhabditis elegansFrom_analysisPanther
WBGene00004347Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004354Caenorhabditis elegansFrom_analysisPanther
WBGene00004353Caenorhabditis elegansFrom_analysisPanther
WBGene00004350Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001145Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001179Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004349Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionrgs-2 encodes a regulator of G protein signaling; by homology, RGS-2 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-2 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-2 appears to function redundantly with rgs-1 to regulate egg-laying behavior when animals are refed following starvation; rgs-2 is expressed in pharyngeal and uterine muscles and in a subset of neurons, including neurons in the ventral cord and head- and tail-ganglia.Paper_evidenceWBPaper00004281
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Expressed in head neurons; pharyngeal muscle cell; tail neurons; uterine muscle; and ventral cord neurons. Is an ortholog of human RGS19 (regulator of G protein signaling 19).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF16H9.1a
F16H9.1b
F16H9.1c
F16H9.1d
Corresponding_transcriptF16H9.1a.1
F16H9.1b.1
F16H9.1c.1
F16H9.1d.1
Other_sequence (40)
Associated_feature (22)
Experimental_infoRNAi_resultWBRNAi00112305Inferred_automaticallyRNAi_primary
WBRNAi00044841Inferred_automaticallyRNAi_primary
WBRNAi00013436Inferred_automaticallyRNAi_primary
WBRNAi00031054Inferred_automaticallyRNAi_primary
WBRNAi00112304Inferred_automaticallyRNAi_primary
WBRNAi00112307Inferred_automaticallyRNAi_primary
WBRNAi00112306Inferred_automaticallyRNAi_primary
WBRNAi00112303Inferred_automaticallyRNAi_primary
WBRNAi00112308Inferred_automaticallyRNAi_primary
WBRNAi00112309Inferred_automaticallyRNAi_primary
Expr_patternExpr1049
Expr11589
Expr1019382
Expr1032163
Expr1148805
Expr2015325
Expr2033559
Drives_constructWBCnstr00000298
WBCnstr00004866
WBCnstr00008978
WBCnstr00010049
WBCnstr00035551
Construct_productWBCnstr00004866
WBCnstr00010049
WBCnstr00035551
AntibodyWBAntibody00001586
Microarray_results (34)
Expression_cluster (158)
Interaction (33)
Map_infoMapXPosition8.11575Error0.023369
PositivePositive_cloneF16H9Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4581
4634
5420
Pseudo_map_position
ReferenceWBPaper00004281
WBPaper00004502
WBPaper00005080
WBPaper00010551
WBPaper00011223
WBPaper00011274
WBPaper00023092
WBPaper00029025
WBPaper00030979
WBPaper00032108
WBPaper00034288
WBPaper00038491
WBPaper00043501
WBPaper00043948
WBPaper00048832
WBPaper00051547
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene