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WormBase Tree Display for Gene: WBGene00001145

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Name Class

WBGene00001145EvidenceCGC_data_submission
SMapS_parentSequenceC16C2
IdentityVersion1
NameCGC_nameeat-16Person_evidenceWBPerson32
Sequence_nameC16C2.2
Molecular_nameC16C2.2a
C16C2.2a.1
CE17404
C16C2.2b
CE30491
C16C2.2b.1
Other_namesag-2
CELE_C16C2.2Accession_evidenceNDBBX284601
Public_nameeat-16
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:23WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classeat
Allele (53)
Legacy_information[Leon Avery] Strong Eat: slippery isthmus and corpus.
See also ad702
[C.elegansII] ad702 : strong Eat: slippery isthmus and corpus. [Avery 1993; DA]
StrainWBStrain00022805
WBStrain00023483
WBStrain00026411
WBStrain00004787
WBStrain00005505
WBStrain00022017
RNASeq_FPKM (74)
GO_annotation (27)
Ortholog (38)
ParalogWBGene00001179Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004344Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004345Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004347Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004349Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004350Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionThe eat-16 gene encodes an RGS protein that affects movement, pharyngeal pumping, egg laying, and synaptic transmission; it genetically interacts with the egl-30 and goa-1 signaling pathways, and is expressed in excitable cells and in the spermatheca.Paper_evidenceWBPaper00004713
WBPaper00004721
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables GTPase activator activity. Involved in several processes, including phospholipase C-inhibiting G protein-coupled receptor signaling pathway; regulation of cell communication; and response to monoamine. Located in cytoplasm; neuron projection; and plasma membrane. Expressed in HSNL; HSNR; neurons; pharyngeal muscle cell; and vulval muscle. Human ortholog(s) of this gene implicated in bradyopsia 1. Is an ortholog of human RGS9 (regulator of G protein signaling 9).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070363Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10004)
Molecular_infoCorresponding_CDSC16C2.2a
C16C2.2b
Corresponding_CDS_historyC16C2.2:wp77
Corresponding_transcriptC16C2.2a.1
C16C2.2b.1
Other_sequence (34)
Associated_featureWBsf643615
WBsf655796
WBsf656787
WBsf218329
WBsf218330
WBsf218331
Experimental_infoRNAi_result (16)
Expr_patternExpr1333
Expr8085
Expr8866
Expr8867
Expr1022292
Expr1030727
Expr1144733
Expr2011152
Expr2029388
Drives_constructWBCnstr00004867
WBCnstr00005925
WBCnstr00010225
WBCnstr00013101
Construct_productWBCnstr00004867
WBCnstr00005925
WBCnstr00010225
WBCnstr00013101
AntibodyWBAntibody00002110
Microarray_results (33)
Expression_cluster (105)
Interaction (54)
Anatomy_functionWBbtf0195
WBbtf0990
Map_infoMapIPosition3.86852Error0.003422
Well_ordered
PositivePositive_cloneC16C2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point2469
2470
4866
4836
Landmark_gene
Reference (94)
RemarkInteracting_genes '[Leon Avery] unc-31: Partially suppresses the Unc phenotype of unc-31.
Sequence From: paul sternberg via ACEDB feedback page <pws@caltech.edu>
Sequence connection from [Hadju-Cronin YM, Sternberg PS]
old_name sag-2 becomes new_name eat-16 from [Hadju-Cronin Y, Sternberg PW].
MethodGene