WormBase Tree Display for Gene: WBGene00004345

WBGene00004345 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 1
    Name: CGC_name: rgs-2 Person_evidence: WBPerson330
      Sequence_name: F16H9.1
      Molecular_name (12)
      Other_name: CELE_F16H9.1 Accession_evidence: NDB BX284606
      Public_name: rgs-2
    DB_info: Database: AceView gene XN345
        WormQTL gene WBGene00004345
        WormFlux gene WBGene00004345
        NDB locus_tag CELE_F16H9.1
        Panther gene CAEEL|WormBase=WBGene00004345|UniProtKB=P49808
          family PTHR10845
        NCBI gene 181414
        RefSeq protein NM_001270270.5
            NM_001392863.1
            NM_077723.6
            NM_001129662.4
        SwissProt UniProtAcc P49808
        TrEMBL UniProtAcc G5EFV0
            G5ECA3
            G5EFC5
        UniProt_GCRP UniProtAcc P49808
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rgs
    Allele (258)
    Strain: WBStrain00026362
      WBStrain00026360
    RNASeq_FPKM (74)
    GO_annotation: 00011399
      00047258
    Ortholog (47)
    Paralog: WBGene00004344 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00004346 Caenorhabditis elegans From_analysis: Panther
      WBGene00004347 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00004354 Caenorhabditis elegans From_analysis: Panther
      WBGene00004353 Caenorhabditis elegans From_analysis: Panther
      WBGene00004350 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001145 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001179 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004349 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: rgs-2 encodes a regulator of G protein signaling; by homology, RGS-2 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-2 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-2 appears to function redundantly with rgs-1 to regulate egg-laying behavior when animals are refed following starvation; rgs-2 is expressed in pharyngeal and uterine muscles and in a subset of neurons, including neurons in the ventral cord and head- and tail-ganglia. Paper_evidence: WBPaper00004281
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Expressed in head neurons; pharyngeal muscle cell; tail neurons; uterine muscle; and ventral cord neurons. Is an ortholog of human RGS19 (regulator of G protein signaling 19). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F16H9.1a
      F16H9.1b
      F16H9.1c
      F16H9.1d
    Corresponding_transcript: F16H9.1a.1
      F16H9.1b.1
      F16H9.1c.1
      F16H9.1d.1
    Other_sequence (40)
    Associated_feature (22)
  Experimental_info: RNAi_result: WBRNAi00112305 Inferred_automatically: RNAi_primary
      WBRNAi00044841 Inferred_automatically: RNAi_primary
      WBRNAi00013436 Inferred_automatically: RNAi_primary
      WBRNAi00031054 Inferred_automatically: RNAi_primary
      WBRNAi00112304 Inferred_automatically: RNAi_primary
      WBRNAi00112307 Inferred_automatically: RNAi_primary
      WBRNAi00112306 Inferred_automatically: RNAi_primary
      WBRNAi00112303 Inferred_automatically: RNAi_primary
      WBRNAi00112308 Inferred_automatically: RNAi_primary
      WBRNAi00112309 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1049
      Expr11589
      Expr1019382
      Expr1032163
      Expr1148805
      Expr2015325
      Expr2033559
    Drives_construct: WBCnstr00000298
      WBCnstr00004866
      WBCnstr00008978
      WBCnstr00010049
      WBCnstr00035551
    Construct_product: WBCnstr00004866
      WBCnstr00010049
      WBCnstr00035551
    Antibody: WBAntibody00001586
    Microarray_results (34)
    Expression_cluster (158)
    Interaction (33)
  Map_info: Map: X Position: 8.11575 Error: 0.023369
    Positive: Positive_clone: F16H9 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4581
        4634
        5420
    Pseudo_map_position
  Reference (17)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene