WormBase Tree Display for Gene: WBGene00004349
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| WBGene00004349 | SMap | S_parent | Sequence | C41G11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | rgs-6 | Person_evidence | WBPerson330 | |||||
| Sequence_name | C41G11.3 | ||||||||
| Molecular_name | C41G11.3a | ||||||||
| C41G11.3a.1 | |||||||||
| CE50026 | |||||||||
| C41G11.3b | |||||||||
| CE49999 | |||||||||
| C41G11.3a.2 | |||||||||
| C41G11.3a.3 | |||||||||
| C41G11.3b.1 | |||||||||
| Other_name | CELE_C41G11.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | rgs-6 | ||||||||
| DB_info | Database | AceView | gene | XG340 | |||||
| WormQTL | gene | WBGene00004349 | |||||||
| WormFlux | gene | WBGene00004349 | |||||||
| NDB | locus_tag | CELE_C41G11.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004349|UniProtKB=Q18563 | |||||||
| family | PTHR10845 | ||||||||
| NCBI | gene | 180840 | |||||||
| RefSeq | protein | NM_001307891.4 | |||||||
| NM_001307892.4 | |||||||||
| SwissProt | UniProtAcc | Q18563 | |||||||
| UniProt_GCRP | UniProtAcc | Q18563 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 03 Dec 2004 16:41:47 | WBPerson2970 | Event | Acquires_merge | WBGene00016569 | ||||
| Acquires_merge | WBGene00016569 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rgs | ||||||||
| Allele (240) | |||||||||
| Strain | WBStrain00026364 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00061662 | ||||||||
| 00112702 | |||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00001145 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00001179 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00004344 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00004345 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00004347 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00004350 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | rgs-6 encodes a regulator of G protein signaling; by homology, RGS-6 is predicted to function as a GTPase-activating protein that binds G protein alpha subunits and negatively regulates heterotrimeric G protein signaling; loss of rgs-6 activity via RNAi or a deletion mutation results in no obvious defects, and likewise, rgs-6 overexpression has no measurable effect on egg-laying behavior, locomotion, or viability; the rgs-6 expression pattern has not yet been reported. | Paper_evidence | WBPaper00004281 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00024480 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 07 Feb 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Human ortholog(s) of this gene implicated in nephrolithiasis. Is an ortholog of human RGS14 (regulator of G protein signaling 14). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:585 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9996) | ||||
| Molecular_info | Corresponding_CDS | C41G11.3a | |||||||
| C41G11.3b | |||||||||
| Corresponding_CDS_history | C41G11.3:wp222 | ||||||||
| C41G11.3:wp244 | |||||||||
| Corresponding_transcript | C41G11.3a.1 | ||||||||
| C41G11.3a.2 | |||||||||
| C41G11.3a.3 | |||||||||
| C41G11.3b.1 | |||||||||
| Other_sequence (25) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00042296 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00011837 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042297 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00011836 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00029726 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1028228 | ||||||||
| Expr1032167 | |||||||||
| Expr1146287 | |||||||||
| Expr2015329 | |||||||||
| Expr2033563 | |||||||||
| Drives_construct | WBCnstr00035548 | ||||||||
| Construct_product | WBCnstr00035548 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (181) | |||||||||
| Interaction | WBInteraction000238889 | ||||||||
| WBInteraction000239010 | |||||||||
| WBInteraction000281121 | |||||||||
| WBInteraction000293836 | |||||||||
| WBInteraction000331002 | |||||||||
| WBInteraction000402075 | |||||||||
| WBInteraction000414237 | |||||||||
| Map_info | Map | X | Position | -4.38493 | Error | 0.002604 | |||
| Positive | Positive_clone | C41G11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5034 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00004281 | ||||||||
| WBPaper00011274 | |||||||||
| WBPaper00031448 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00064400 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
