WormBase Tree Display for Gene: WBGene00004353

WBGene00004353 SMap: S_parent: Sequence: F45B8
  Identity: Version: 2
    Name: CGC_name: rgs-10 Person_evidence: WBPerson330
      Sequence_name: F45B8.2
      Molecular_name: F45B8.2
        F45B8.2.1
        CE10430
      Other_name: tag-215 Curator_confirmed: WBPerson2970
        CELE_F45B8.2 Accession_evidence: NDB BX284606
      Public_name: rgs-10
    DB_info: Database: AceView gene XP581
        WormQTL gene WBGene00004353
        WormFlux gene WBGene00004353
        NDB locus_tag CELE_F45B8.2
        Panther gene CAEEL|WormBase=WBGene00004353|UniProtKB=O45523
          family PTHR10845
        NCBI gene 185764
        RefSeq protein NM_078081.2
        SwissProt UniProtAcc O45523
        UniProt_GCRP UniProtAcc O45523
        OMIM gene 603276
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 03 Dec 2004 16:57:36 WBPerson2970 Event: Acquires_merge: WBGene00009719
      Acquires_merge: WBGene00009719
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rgs
    Allele (38)
    Strain: WBStrain00026378
      WBStrain00031781
      WBStrain00035991
    RNASeq_FPKM (74)
    GO_annotation: 00034709
      00034710
      00034711
    Ortholog (44)
    Paralog: WBGene00004344 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00004345 Caenorhabditis elegans From_analysis: Panther
      WBGene00004346 Caenorhabditis elegans From_analysis: Panther
      WBGene00004347 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00004350 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00004351 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00004352 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00021988 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00004354 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Involved in embryo development and reproduction. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma and essential hypertension. Is an ortholog of several human genes including RGS1 (regulator of G protein signaling 1); RGS2 (regulator of G protein signaling 2); and RGS4 (regulator of G protein signaling 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10825 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10001)
      DOID:0050861 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10001)
  Molecular_info: Corresponding_CDS: F45B8.2
    Corresponding_transcript: F45B8.2.1
    Associated_feature: WBsf1008050
  Experimental_info: RNAi_result: WBRNAi00047346 Inferred_automatically: RNAi_primary
      WBRNAi00061483 Inferred_automatically: RNAi_primary
      WBRNAi00014974 Inferred_automatically: RNAi_primary
      WBRNAi00032272 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1027844
      Expr1032170
      Expr1151199
      Expr2015322
      Expr2033556
    Drives_construct: WBCnstr00035544
    Construct_product: WBCnstr00035544
    Microarray_results (15)
    Expression_cluster (125)
    Interaction (50)
  Map_info: Map: X Position: 21.5995 Error: 0.003428
    Positive: Positive_clone: F45B8 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5033
        5052
    Pseudo_map_position
  Reference: WBPaper00004281
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene