Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00004346

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00004346SMapS_parentSequenceCHROMOSOME_II
IdentityVersion1
NameCGC_namergs-3Person_evidenceWBPerson330
Sequence_nameC29H12.3
Molecular_name (13)
Other_nameCELE_C29H12.3Accession_evidenceNDBBX284602
Public_namergs-3
DB_infoDatabaseAceViewgene2G399
WormQTLgeneWBGene00004346
WormFluxgeneWBGene00004346
NDBlocus_tagCELE_C29H12.3
PanthergeneCAEEL|WormBase=WBGene00004346|UniProtKB=Q18312
familyPTHR10845
NCBIgene174020
RefSeqproteinNM_062822.4
NM_001393090.1
NM_182096.6
SwissProtUniProtAccQ18312
TrEMBLUniProtAccQ5DX43
Q8MQB2
UniProt_GCRPUniProtAccQ18312
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrgs
Allele (114)
StrainWBStrain00026361
WBStrain00032471
RNASeq_FPKM (74)
GO_annotation00060895
00060896
00060897
00060898
00060899
00060900
00060901
Ortholog (28)
ParalogWBGene00004344Caenorhabditis elegansFrom_analysisPanther
WBGene00004345Caenorhabditis elegansFrom_analysisPanther
WBGene00004350Caenorhabditis elegansFrom_analysisPanther
WBGene00004347Caenorhabditis elegansFrom_analysisPanther
WBGene00004354Caenorhabditis elegansFrom_analysisPanther
WBGene00004353Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionrgs-3 encodes three proteins containing two RGS (regulator of G protein signaling) domains, the more C-terminal of which is most similar to those of the mammalian brain-specific RGS, RGS8; rgs-3 activity is required for normal G protein-mediated response to a number of sensory stimuli, including odorants, high osmolarity, and nose touch off food; genetic analyses indicate that RGS-3 functions to decrease G protein signaling in sensory neurons and increase glutamatergic synaptic transmission from sensory to interneurons; RGS-3::GFP fusion proteins are expressed exclusively in nine pairs of sensory neurons from late stages of embryogenesis through adulthood.Paper_evidenceWBPaper00028963
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated24 Apr 2007 00:00:00
Automated_descriptionInvolved in chemosensory behavior and sensory perception of bitter taste. Expressed in amphid neurons and phasmid neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC29H12.3a
C29H12.3b
C29H12.3c
Corresponding_transcriptC29H12.3a.1
C29H12.3a.2
C29H12.3b.1
C29H12.3b.2
C29H12.3c.1
C29H12.3c.2
C29H12.3c.3
Other_sequence (24)
Associated_feature (13)
Experimental_infoRNAi_resultWBRNAi00011368Inferred_automaticallyRNAi_primary
WBRNAi00000844Inferred_automaticallyRNAi_primary
WBRNAi00041511Inferred_automaticallyRNAi_primary
WBRNAi00029341Inferred_automaticallyRNAi_primary
WBRNAi00065514Inferred_automaticallyRNAi_primary
Expr_patternExpr2043
Expr4511
Expr1024036
Expr1032164
Expr1145535
Expr2015326
Expr2033560
Drives_constructWBCnstr00012069
WBCnstr00035550
Construct_productWBCnstr00007781
WBCnstr00012069
WBCnstr00035550
Microarray_results (35)
Expression_cluster (131)
InteractionWBInteraction000361960
WBInteraction000368226
WBInteraction000418318
WBInteraction000423849
WBInteraction000569525
WBInteraction000569527
Map_infoMapIIPosition-0.485213Error0.010992
PositivePositive_cloneC29H12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4907
4305
5045
Pseudo_map_position
Reference (15)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene