| WBGene00003968 | SMap | S_parent | Sequence | T14F9 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | peb-1 | Person_evidence | WBPerson460 |
| | | Sequence_name | T14F9.4 |
| | | Molecular_name | T14F9.4a |
| | | | T14F9.4a.1 |
| | | | CE07500 |
| | | | T14F9.4b |
| | | | CE48479 |
| | | | T14F9.4c |
| | | | CE53821 |
| | | | T14F9.4b.1 |
| | | | T14F9.4c.1 |
| | | Other_name | CELE_T14F9.4 | Accession_evidence | NDB | BX284606 |
| | | Public_name | peb-1 |
| | DB_info | Database | AceView | gene | XC837 |
| | | | WormQTL | gene | WBGene00003968 |
| | | | WormFlux | gene | WBGene00003968 |
| | | | NDB | locus_tag | CELE_T14F9.4 |
| | | | NCBI | gene | 180532 |
| | | | RefSeq | protein | NM_001377613.2 |
| | | | | | NM_001377612.2 |
| | | | | | NM_001029739.6 |
| | | | SwissProt | UniProtAcc | A0A5S9MMK5 |
| | | | TREEFAM | TREEFAM_ID | TF316476 |
| | | | UniProt_GCRP | UniProtAcc | A0A5S9MMK5 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | peb |
| | Allele (125) |
| | Strain | WBStrain00029947 |
| | | WBStrain00036952 |
| | RNASeq_FPKM (74) |
| | GO_annotation | 00004140 |
| | | 00004141 |
| | | 00004142 |
| | | 00004143 |
| | | 00004144 |
| | | 00004145 |
| | | 00004146 |
| | | 00004147 |
| | Ortholog (24) |
| | Structured_description | Concise_description | peb-1 encodes a novel DNA-binding protein; during development, peb-1 activity is required for proper morphogenesis of the pharynx, vulva, and hindgut and for normal molting, feeding, and body morphology; in vitro, PEB-1 exhibits sequence-specific DNA binding to a regulatory sequence known as subelement C, which directs pharynx-specific myo-2 expression and in yeast, PEB-1 exhibits modest transcription activation activity; PEB-1 is expressed in the nuclei of all pharyngeal cells (except neurons) from the comma stage of embryogenesis through late larval stages; in addition, PEB-1 is expressed dynamically in non-pharyngeal cells, including the vulva, germline, hindgut, and hypodermis. | Paper_evidence | WBPaper00004526 |
| | | | | | WBPaper00005395 |
| | | | | | WBPaper00013471 |
| | | | | | WBPaper00024643 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 10 Sep 2007 00:00:00 |
| | | Automated_description | Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including germ line; hypodermis; pharyngeal cell; pharyngeal-intestinal valve; and rectal epithelial cell. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | T14F9.4a |
| | | T14F9.4b |
| | | T14F9.4c |
| | Corresponding_CDS_history | T14F9.4b:wp238 |
| | Corresponding_transcript | T14F9.4a.1 |
| | | T14F9.4b.1 |
| | | T14F9.4c.1 |
| | Other_sequence (13) |
| | Associated_feature (25) |
| | Gene_product_binds (63) |
| | Transcription_factor | WBTranscriptionFactor000462 |
| Experimental_info | RNAi_result (14) |
| | Expr_pattern (15) |
| | Drives_construct | WBCnstr00000382 |
| | | WBCnstr00010458 |
| | | WBCnstr00011371 |
| | | WBCnstr00020648 |
| | Construct_product | WBCnstr00000308 |
| | | WBCnstr00000309 |
| | | WBCnstr00010458 |
| | | WBCnstr00016765 |
| | | WBCnstr00016871 |
| | | WBCnstr00020648 |
| | Antibody | WBAntibody00000344 |
| | Microarray_results (26) |
| | Expression_cluster | WBPaper00024505:pharyngeal_enriched |
| | | WBPaper00032425:down_in_lin-35 |
| | | WBPaper00032528:L3_enriched |
| | | WBPaper00033065:cyc-1(RNAi)_upregulated |
| | | WBPaper00035197:fer-1_downregulated |
| | | WBPaper00036375:enriched_in_PVD_OLL |
| | | WBPaper00037950:coelomocytes_L2-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:hypodermis_L1-larva_expressed |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:intestine_L1-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray |
| | | WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray |
| | | WBPaper00040221:DAF-12_target_ALF4 |
| | | WBPaper00041222:unc-120(st364)_downregulated |
| | | WBPaper00042194:nhr-114(RNAi)_downregulated |
| | | WBPaper00042215:wdr-23(tm1817)_upregulated |
| | | WBPaper00042561:smgl-1(RNAi)_downregulated |
| | | WBPaper00042561:smgl-2(RNAi)_upregulated |
| | | WBPaper00043945:MeHg_upregulated |
| | | WBPaper00044426:rotenone_24h_downregulated |
| | | WBPaper00044578:reduced-humidity_downregulated_microarray |
| | | WBPaper00044736:oscillating_dev_expression |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated |
| | | WBPaper00045316:prg-1_upregulated_L1 |
| | | WBPaper00045316:prg-1_upregulated_L2 |
| | | WBPaper00045316:prg-1_upregulated_L3 |
| | | WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h |
| | | WBPaper00048611:MnCl2_upregulated |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049217:DAF-16_upregulated |
| | | WBPaper00049498:npr-1(ur89)_regulated_4 |
| | | WBPaper00049545:cco-1(RNAi)_upregulated |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated |
| | | WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi) |
| | | WBPaper00049942:hsf-1(RNAi)_upregulated |
| | | WBPaper00050015:ifg-1(RNAi)_upregulated |
| | | WBPaper00050370:dpy-21(e428)_L3_upregulated |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C |
| | | WBPaper00050726:OsmoticStress_regulated_NoFood |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:body-muscle_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00050990:seam_expressed |
| | | WBPaper00051404:alg-2(ok304)_downregulated |
| | | WBPaper00051498:zinc-reduction_upregulated |
| | | WBPaper00052884:emb-4(hc60)_upregulated |
| | | WBPaper00053020:sid-3(ok973)_upregulated |
| | | WBPaper00053184:sma-2(rax5)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053318:Aging_upregulated_mRNA_N2 |
| | | WBPaper00053318:mir-71(n4115)_upregulated_mRNA |
| | | WBPaper00053388:dauer_regulated_Cluster3 |
| | | WBPaper00053402:cco-1(RNAi)_upregulated |
| | | WBPaper00054493:hpl-2(tm1489)_upregulated |
| | | WBPaper00055334:DLC-1_interacting |
| | | WBPaper00055354:eat-2(ad1116)_upregulated |
| | | WBPaper00055354:Rapamycin-Allantoin_downregulated |
| | | WBPaper00055862:antimycin_damt-1(gk961032)_regulated |
| | | WBPaper00055941:atfs-1(et15)_upregulated |
| | | WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_downregulated |
| | | WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047) |
| | | WBPaper00056090:E.faecalis_upregulated_N2 |
| | | WBPaper00056165:MINA-1_interacting_mRNA |
| | | WBPaper00056169:rrf-3(pk1426)_downregulated_L4 |
| | | WBPaper00056169:rrf-3(pk1426)_upregulated_embryo |
| | | WBPaper00056169:rrf-3(pk1426)_upregulated_L1 |
| | | WBPaper00056169:rrf-3(pk1426)_upregulated_L2 |
| | | WBPaper00056290:hsp-6(mg585)_upregulated |
| | | WBPaper00056443:sek-1(km4)_upregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated |
| | | WBPaper00056471:S.aureus-4h_upregulated_N2 |
| | | WBPaper00056617:adr-1_upregulated_L4_transcript |
| | | WBPaper00056617:adr-2_upregulated_L4_transcript |
| | | WBPaper00056826:SGP_biased |
| | | WBPaper00056868:P.aeruginosa_upregulated_smallRNA |
| | | WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C |
| | | WBPaper00057041:spc-1(cas971)_upregulated |
| | | WBPaper00057041:unc-70(cas983)_upregulated |
| | | WBPaper00057068:numr-1(RNAi)_downregulated |
| | | WBPaper00057068:numr-1(RNAi)_downregulated_Cadmium |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058691:set-2(bn129)_upregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00059231:alh-6(lax105)_L4_upregulated |
| | | WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059754:E.faecalis_OG1RF_upregulated |
| | | WBPaper00060014:set-2(tm1630)_downregulated |
| | | WBPaper00060084:cco-1(RNAi)_downregulated_N2 |
| | | WBPaper00060100:SiNP_upregulated_mRNA |
| | | WBPaper00060273:isp-1(qm150)_upregulated |
| | | WBPaper00060273:vrk-1(RNAi)_downregulated |
| | | WBPaper00060445:ikb-1(nr2027)_downregulated_L4 |
| | | WBPaper00060445:nfki-1(cer1)_downregulated_L4 |
| | | WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_downregulated_L4 |
| | | WBPaper00060683:hlh-11(ko1)_upregulated |
| | | WBPaper00060703:nas-38(ok3407)_upregulated |
| | | WBPaper00060764:swsn-1(os22ts)_downregulated |
| | | WBPaper00060871:M.humicola-infection_48h_regulated |
| | | WBPaper00060909:atfs-1(cmh15)_downregulated |
| | | WBPaper00060911:prx-5(RNAi)_upregulated_mRNA |
| | | WBPaper00061007:S.aquatilis_upregulated |
| | | WBPaper00061081:E.faecalis_upregulated_N2 |
| | | WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640) |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061340:Anterior_arcade_cell |
| | | WBPaper00061340:CEPso |
| | | WBPaper00061340:F_U |
| | | WBPaper00061340:g1A_g1P |
| | | WBPaper00061340:g2 |
| | | WBPaper00061340:G2_and_W_blasts |
| | | WBPaper00061340:Glia |
| | | WBPaper00061340:hyp1V_and_ant_arc_V |
| | | WBPaper00061340:hyp1_hyp2 |
| | | WBPaper00061340:K_Kprime |
| | | WBPaper00061340:mc1 |
| | | WBPaper00061340:mc2 |
| | | WBPaper00061340:mc3 |
| | | WBPaper00061340:pm1_pm2 |
| | | WBPaper00061340:pm6 |
| | | WBPaper00061340:pm7 |
| | | WBPaper00061340:pm8 |
| | | WBPaper00061340:rect_D |
| | | WBPaper00061341:28C_24h_upregulated |
| | | WBPaper00061341:28C_48h_upregulated |
| | | WBPaper00061409:neuronal-fzo-1(RNAi)_upregulated |
| | | WBPaper00061439:unc-30(ok613)_upregulated |
| | | WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection |
| | | WBPaper00061479:hda-1(ne4752)_upregulated |
| | | WBPaper00061527:rgs-2_11061-pde-1 |
| | | WBPaper00061527:tnt-4-myo-1_2160 |
| | | WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated |
| | | WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated |
| | | WBPaper00061753:csr-1(tor159)_upregulated_25C |
| | | WBPaper00062156:jmjd-5(zr1234)_upregulated |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062193:skn-1(RNAi)_upregulated |
| | | WBPaper00062325:muscle_enriched_coding-RNA |
| | | WBPaper00062354:H.zoospora_6h_regulated |
| | | WBPaper00062440:crh-1(n3315)_downregulated |
| | | WBPaper00062440:crh-1(syb385)_downregulated |
| | | WBPaper00062446:nhr-8(hd117)_upregulated |
| | | WBPaper00062684:pathogen_upregulated_N2 |
| | | WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA |
| | | WBPaper00064005:starvation_upregulated_N2_mRNA |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064107:lin-35(n745)_upregulated |
| | | WBPaper00064156:lipl-4(overexpress)_upregulated |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064632:daf-2(e1370)_upregulated_intestine |
| | | WBPaper00064661:lpd-3(ok2138)_upregulated |
| | | WBPaper00064769:him-17(me24)_downregulated |
| | | WBPaper00064788:ketamine_upregulated |
| | | WBPaper00064871:hypoxia_downregulated_F3 |
| | | WBPaper00064933:bcf-1(ylf1)_upregulated_transcript |
| | | WBPaper00064999:miR-229-64-65-66_downregulated |
| | | WBPaper00065086:JU1400_N.ausubeli_regulated |
| | | WBPaper00065086:JU1400_N.ferruginous_regulated |
| | | WBPaper00065225:nhr-42(tm1375)_upregulated_uninfected |
| | | WBPaper00065272:dhgd-1(tm6671)_upregulated |
| | | WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977) |
| | | WBPaper00065749:Heat-Shock_downregulated_N2 |
| | | WBPaper00065993:glp-1(e2141)_upregulated |
| | | WBPaper00066062:xrep-4(lax137)_upregulated |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | cgc4489_group_20 |
| | | WBPaper00024393:strongly_regulated_dauer_genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026629:L2_male_enriched |
| | | WBPaper00026929:Resveratrol_regulated_daf-16 |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00026952:class_A |
| | | WBPaper00027111:rrf-2(ok210)_upregulated |
| | | WBPaper00030985:Serratia_marcesens_downregulated |
| | | WBPaper00031003:0hr_muscle_depleted |
| | | WBPaper00031003:24hr_muscle_enriched |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00031003:total_muscle_enriched |
| | | WBPaper00031252:AIN-1_IP_enriched |
| | | WBPaper00031532:Larva_Pan_Neuronal_Depleted |
| | | WBPaper00031832:slr-2_regulated |
| | | WBPaper00034739:N2lessDR1350 |
| | | WBPaper00035588:alg-1(-)_upregulated |
| | | WBPaper00035905:FBF-1_Associated |
| | | WBPaper00036286:Pattern_G |
| | | WBPaper00038172:aak-2overexpression_down_regulated |
| | | WBPaper00038304:octr-1_regulated |
| | | WBPaper00039866:ClassComp_daf-19_upregulated |
| | | WBPaper00040185:nhr-23(RNAi)_downregulated |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2 |
| | | WBPaper00041002:HQ_3d_2.0mM_Up |
| | | WBPaper00041174:genotypic |
| | | WBPaper00041174:genotypic_prime |
| | | WBPaper00042236:flcn-1(ok975)_upregulated |
| | | WBPaper00042331:a-SWCNTs_downregulated |
| | | WBPaper00045015:nhr-25(RNAi)_upregulated |
| | | WBPaper00045263:0.1mM-paraquat_upregulated |
| | | WBPaper00045263:isp-1(qm150)_upregulated |
| | | WBPaper00045960:L1-L4-lethargus_downregulated |
| | | WBPaper00045960:L4-lethargus_downregulated |
| | | WBPaper00046548:dafachronic-acid_upregulated |
| | | WBPaper00047070:N2_UV_upregulated |
| | | WBPaper00047070:xpa-1_UV_upregulated |
| | | WBPaper00048989:eat-2(ad465)_rapamycin_downregulated |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | | WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo |
| | | WBPaper00055899:nitroguanidine_regulated |
| | | WBPaper00056330:mrps-5(RNAi)_upregulated |
| | | WBPaper00057098:SiO2-nanoparticles_upregulated |
| | | [cgc6390]:Cluster_A |
| | Interaction (57) |
| Map_info | Map | X | Position | -16.6045 | Error | 0.136176 |
| | Positive | Positive_clone | T14F9 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference (22) |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
