WormBase Tree Display for Gene: WBGene00003774
expand all nodes | collapse all nodes | view schema
WBGene00003774 | SMap | S_parent | Sequence | F07F6 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | nmr | |||||
Allele (99) | ||||||
Strain | WBStrain00040167 | |||||
WBStrain00002755 | ||||||
WBStrain00040168 | ||||||
WBStrain00040666 | ||||||
WBStrain00040171 | ||||||
WBStrain00040796 | ||||||
WBStrain00054658 | ||||||
WBStrain00054659 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (32) | ||||||
Ortholog (37) | ||||||
Paralog | WBGene00001612 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||
WBGene00001613 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00001614 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00001615 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00001616 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00001617 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00001618 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00001619 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00003775 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00012190 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
Structured_description | Concise_description | nmr-1 encodes an NMDA-type ionotropic glutamate receptor subunit that affects the duration of forward movement which is important during foraging behavior, and also affects osmotic avoidance; the slow kinetics typical of NMDA-dependent currents are likely important for its effect on forward movement. | Paper_evidence | WBPaper00004836 | ||
WBPaper00005622 | ||||||
Curator_confirmed | WBPerson48 | |||||
Date_last_updated | 04 Mar 2005 00:00:00 | |||||
Automated_description | Predicted to enable ligand-gated monoatomic ion channel activity and signaling receptor activity. Predicted to contribute to NMDA glutamate receptor activity. Involved in locomotory behavior and regulation of forward locomotion. Located in neuron projection; plasma membrane; and synapse. Expressed in several structures, including ganglia; gonadal sheath cell; head mesodermal cell; nerve ring neurons; and oocyte. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; alcohol use disorder; autosomal dominant intellectual developmental disorder 8; and developmental and epileptic encephalopathy 101. Is an ortholog of human GRIN1 (glutamate ionotropic receptor NMDA type subunit 1). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Experimental_model | DOID:1289 | Homo sapiens | Paper_evidence | WBPaper00057034 | |
Curator_confirmed | WBPerson324 | |||||
Date_last_updated | 30 Mar 2021 00:00:00 | |||||
Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||
DOID:0070038 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | |||
DOID:8725 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | |||
DOID:0070387 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | |||
DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | |||
DOID:1574 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | |||
DOID:11206 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | |||
Models_disease_asserted | WBDOannot00000907 | |||||
WBDOannot00000908 | ||||||
Molecular_info | Corresponding_CDS | F07F6.6 | ||||
Corresponding_transcript | F07F6.6.1 | |||||
Other_sequence | Oden_isotig22559 | |||||
JI250035.1 | ||||||
Tcol_isotig18961 | ||||||
Associated_feature | WBsf987884 | |||||
WBsf987885 | ||||||
WBsf1012228 | ||||||
WBsf1012229 | ||||||
WBsf223054 | ||||||
Experimental_info | RNAi_result | WBRNAi00022320 | Inferred_automatically | RNAi_primary | ||
WBRNAi00043920 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00030612 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern (11) | ||||||
Drives_construct (42) | ||||||
Construct_product | WBCnstr00000022 | |||||
WBCnstr00006168 | ||||||
WBCnstr00010811 | ||||||
WBCnstr00011656 | ||||||
WBCnstr00013203 | ||||||
WBCnstr00035874 | ||||||
Microarray_results (19) | ||||||
Expression_cluster (94) | ||||||
Interaction (71) | ||||||
Map_info (4) | ||||||
Reference (105) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |