WormBase Tree Display for Gene: WBGene00001614
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| WBGene00001614 | SMap | S_parent | Sequence | K10D3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | glr-3 | Person_evidence | WBPerson42 | |||||
| Sequence_name | K10D3.1 | ||||||||
| Molecular_name | K10D3.1 | ||||||||
| K10D3.1.1 | |||||||||
| CE36553 | |||||||||
| Other_name | CELE_K10D3.1 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | glr-3 | ||||||||
| DB_info | Database | AceView | gene | 1H697 | |||||
| WormQTL | gene | WBGene00001614 | |||||||
| WormFlux | gene | WBGene00001614 | |||||||
| NDB | locus_tag | CELE_K10D3.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001614|UniProtKB=Q21415 | |||||||
| family | PTHR18966 | ||||||||
| NCBI | gene | 172449 | |||||||
| RefSeq | protein | NM_059616.3 | |||||||
| SwissProt | UniProtAcc | Q21415 | |||||||
| UniProt_GCRP | UniProtAcc | Q21415 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | glr | ||||||||
| Allele (38) | |||||||||
| Strain | WBStrain00002741 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (50) | |||||||||
| Paralog | WBGene00001612 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001613 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001618 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001615 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001616 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001619 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001617 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003774 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00003775 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00012190 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | glr-3 encodes a protein that contains a ligand-gated ion channel domain and a receptor family ligand binding domain with similarity to kainate-selective ionotropic glutamate receptor 2 (human GRIK2); expressed in the RIA neuron. | Paper_evidence | WBPaper00004567 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in detection of cold stimulus involved in thermoception and detection of temperature stimulus involved in sensory perception of pain. Predicted to be located in postsynaptic density membrane. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Is an ortholog of human GRIK3 (glutamate ionotropic receptor kainate type subunit 3) and GRIK4 (glutamate ionotropic receptor kainate type subunit 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3083 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4583) | ||||
| DOID:3328 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4583) | ||||||
| Molecular_info | Corresponding_CDS | K10D3.1 | |||||||
| Corresponding_CDS_history | K10D3.1:wp72 | ||||||||
| K10D3.1:wp122 | |||||||||
| Corresponding_transcript | K10D3.1.1 | ||||||||
| Other_sequence | Acan_isotig13320 | ||||||||
| AS01537 | |||||||||
| JI175081.1 | |||||||||
| ASC24720_1 | |||||||||
| JO468630.1 | |||||||||
| JI237114.1 | |||||||||
| Oden_isotig27467 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00003977 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00050535 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1927 | ||||||||
| Expr818 | |||||||||
| Expr1014391 | |||||||||
| Expr1154240 | |||||||||
| Expr2012114 | |||||||||
| Expr2030350 | |||||||||
| Drives_construct (38) | |||||||||
| Construct_product | WBCnstr00013163 | ||||||||
| WBCnstr00015864 | |||||||||
| WBCnstr00036824 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (73) | |||||||||
| Interaction (37) | |||||||||
| Map_info | Map | I | Position | 1.77475 | Error | 0.005568 | |||
| Positive | Positive_clone | K10D3 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (25) | |||||||||
| Remark | Sequence connection from [Brockie PJ, Maricq AV, Aronoff R], 02/06/11 krb. | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
