WormBase Tree Display for Gene: WBGene00003774
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WBGene00003774 | SMap | S_parent | Sequence | F07F6 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | nmr-1 | Person_evidence | WBPerson404 | |||||
Sequence_name | F07F6.6 | ||||||||
Molecular_name | F07F6.6 | ||||||||
F07F6.6.1 | |||||||||
CE30128 | |||||||||
Other_name | F56D1.b | Curator_confirmed | WBPerson1983 | ||||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
F56D1.c | Curator_confirmed | WBPerson1983 | |||||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
CELE_F07F6.6 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | nmr-1 | ||||||||
DB_info | Database | AceView | gene | 2F732 | |||||
WormQTL | gene | WBGene00003774 | |||||||
WormFlux | gene | WBGene00003774 | |||||||
NDB | locus_tag | CELE_F07F6.6 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00003774|UniProtKB=G5EGQ9 | |||||||
family | PTHR18966 | ||||||||
NCBI | gene | 173929 | |||||||
RefSeq | protein | NM_062632.7 | |||||||
TREEFAM | TREEFAM_ID | TF314731 | |||||||
TrEMBL | UniProtAcc | G5EGQ9 | |||||||
UniProt_GCRP | UniProtAcc | G5EGQ9 | |||||||
OMIM | gene | 138249 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | nmr | ||||||||
Allele (99) | |||||||||
Strain | WBStrain00040167 | ||||||||
WBStrain00002755 | |||||||||
WBStrain00040168 | |||||||||
WBStrain00040666 | |||||||||
WBStrain00040171 | |||||||||
WBStrain00040796 | |||||||||
WBStrain00054658 | |||||||||
WBStrain00054659 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (32) | |||||||||
Ortholog (37) | |||||||||
Paralog | WBGene00001612 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
WBGene00001613 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001614 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001615 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001616 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001617 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001618 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001619 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00003775 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00012190 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | nmr-1 encodes an NMDA-type ionotropic glutamate receptor subunit that affects the duration of forward movement which is important during foraging behavior, and also affects osmotic avoidance; the slow kinetics typical of NMDA-dependent currents are likely important for its effect on forward movement. | Paper_evidence | WBPaper00004836 | |||||
WBPaper00005622 | |||||||||
Curator_confirmed | WBPerson48 | ||||||||
Date_last_updated | 04 Mar 2005 00:00:00 | ||||||||
Automated_description | Predicted to enable ligand-gated monoatomic ion channel activity and signaling receptor activity. Predicted to contribute to NMDA glutamate receptor activity. Involved in locomotory behavior and regulation of forward locomotion. Located in neuron projection; plasma membrane; and synapse. Expressed in several structures, including ganglia; gonadal sheath cell; head mesodermal cell; nerve ring neurons; and oocyte. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; alcohol use disorder; autosomal dominant intellectual developmental disorder 8; and developmental and epileptic encephalopathy 101. Is an ortholog of human GRIN1 (glutamate ionotropic receptor NMDA type subunit 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed (2) | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Experimental_model | DOID:1289 | Homo sapiens | Paper_evidence | WBPaper00057034 | ||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 30 Mar 2021 00:00:00 | ||||||||
Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | |||||
DOID:0070038 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
DOID:8725 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
DOID:0070387 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
DOID:1574 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
DOID:11206 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
Models_disease_asserted | WBDOannot00000907 | ||||||||
WBDOannot00000908 | |||||||||
Molecular_info | Corresponding_CDS | F07F6.6 | |||||||
Corresponding_transcript | F07F6.6.1 | ||||||||
Other_sequence | Oden_isotig22559 | ||||||||
JI250035.1 | |||||||||
Tcol_isotig18961 | |||||||||
Associated_feature | WBsf987884 | ||||||||
WBsf987885 | |||||||||
WBsf1012228 | |||||||||
WBsf1012229 | |||||||||
WBsf223054 | |||||||||
Experimental_info | RNAi_result | WBRNAi00022320 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00043920 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00030612 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (11) | |||||||||
Drives_construct (42) | |||||||||
Construct_product | WBCnstr00000022 | ||||||||
WBCnstr00006168 | |||||||||
WBCnstr00010811 | |||||||||
WBCnstr00011656 | |||||||||
WBCnstr00013203 | |||||||||
WBCnstr00035874 | |||||||||
Microarray_results (19) | |||||||||
Expression_cluster (94) | |||||||||
Interaction (71) | |||||||||
Map_info | Map | II | Position | -1.52008 | Error | 0.016815 | |||
Positive | Positive_clone | F07F6 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4253 | |||||||
4538 | |||||||||
5279 | |||||||||
Pseudo_map_position | |||||||||
Reference (105) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |