WormBase Tree Display for Gene: WBGene00003736

WBGene00003736 SMap: S_parent: Sequence: ZK822
  Identity: Version: 1
    Name: CGC_name: nhx-9
      Sequence_name: ZK822.3
      Molecular_name: ZK822.3a
        ZK822.3a.1
        CE27559
        ZK822.3b
        CE27560
        ZK822.3c
        CE28196
        ZK822.3b.1
        ZK822.3c.1
      Other_name: CELE_ZK822.3 Accession_evidence: NDB BX284604
      Public_name: nhx-9
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:32 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nhx
    Allele (63)
    Strain: WBStrain00031663
    RNASeq_FPKM (74)
    GO_annotation (23)
    Ortholog (49)
    Paralog: WBGene00003729 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003730 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003731 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00003732 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003733 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003734 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003735 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003943 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to be located in plasma membrane. Expressed in excretory cell; intestine; and phasmid sensillum. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 8 and end stage renal disease. Is an ortholog of human SLC9A3 (solute carrier family 9 member A3) and SLC9A5 (solute carrier family 9 member A5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:783 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11078)
      DOID:0060777 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11073)
  Molecular_info: Corresponding_CDS: ZK822.3a
      ZK822.3b
      ZK822.3c
    Corresponding_CDS_history: ZK822.3:wp49
      ZK822.3c:wp61
      ZK822.3c:wp229
    Corresponding_transcript: ZK822.3a.1
      ZK822.3b.1
      ZK822.3c.1
    Other_sequence (25)
    Associated_feature: WBsf216765
      WBsf646433
      WBsf646434
      WBsf646435
      WBsf660771
      WBsf997992
      WBsf229221
      WBsf229222
  Experimental_info: RNAi_result: WBRNAi00086174 Inferred_automatically: RNAi_primary
      WBRNAi00059743 Inferred_automatically: RNAi_primary
      WBRNAi00086173 Inferred_automatically: RNAi_primary
      WBRNAi00059742 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2238
      Expr2248
      Expr1014311
      Expr1031747
      Expr1163167
      Expr2014260
      Expr2032500
    Drives_construct: WBCnstr00010717
      WBCnstr00010728
      WBCnstr00035906
    Construct_product: WBCnstr00010728
      WBCnstr00035906
    Microarray_results: SMD_ZK822.3
      190184_at
      A_12_P108056
      A_12_P145675
      A_12_P145676
      Aff_ZK822.3
      GPL13394_WBGene00003736
      GPL13914_ZK822.3
      GPL14144_ZK822.3b_1406-1465_0.915_10_B
      GPL14144_ZK822.3b_1518-1577_0.909_11_C
      GPL14144_ZK822.3b_1771-1830_0.948_1_A
      GPL19516_CGZ0057589
      GPL19516_CGZ0057590
      GPL19516_CGZ0057591
      GPL19516_CGZ0057592
      GPL21109_ZK822.3a
      GPL3518_CE27560
      GPL3518_CE29015
      GPL8304_CE_WBGene00003736_A
      GPL8304_CE_WBGene00003736_B
      GPL8673_ZK822_3aP00700
      GPL8673_ZK822_3aP01727
      GPL8673_ZK822_3aP01832
      GPL8673_ZK822_3bP00760
      GPL8673_ZK822_3bP01787
      GPL8673_ZK822_3bP01892
      GPL8673_ZK822_3cP00580
      GPL8673_ZK822_3cP01607
      GPL8673_ZK822_3cP01709
      GPL9450_ZK822.3a
      GPL9450_ZK822.3b
      GPL9450_ZK822.3c
      cea2.d.07629
      cea2.d.07630
      cea2.d.49805
    Expression_cluster (165)
    Interaction (29)
  Map_info: Map: IV Position: 5.41637 Error: 0.003754
    Positive: Positive_clone: ZK822 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4302
    Pseudo_map_position
  Reference: WBPaper00018859
    WBPaper00035475
    WBPaper00038491
    WBPaper00047401
    WBPaper00055090
    WBPaper00064064
  Remark: Sequence connection from [Nehrke K, Melvin J]
    nxh-2 nxh-3 nxh-4 nxh-5 nxh-6 nxh-7 nxh-8 nxh-9 published in cgc5421 actually refer to nhx genes CGC_data_submission
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene