| WBGene00003003 | SMap | S_parent | Sequence | T25C12 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | lin-14 | Person_evidence | WBPerson261 |
| | | Sequence_name | T25C12.1 |
| | | Molecular_name | T25C12.1a |
| | | | T25C12.1a.1 |
| | | | CE43285 |
| | | | T25C12.1b |
| | | | CE03734 |
| | | | T25C12.1b.1 |
| | | Other_name | CELE_T25C12.1 | Accession_evidence | NDB | BX284606 |
| | | Public_name | lin-14 |
| | DB_info | Database | AceView | gene | XM103 |
| | | | WormQTL | gene | WBGene00003003 |
| | | | WormFlux | gene | WBGene00003003 |
| | | | NDB | locus_tag | CELE_T25C12.1 |
| | | | NCBI | gene | 181337 |
| | | | RefSeq | protein | NM_077515.5 |
| | | | | | NM_077516.7 |
| | | | SwissProt | UniProtAcc | Q21446 |
| | | | TREEFAM | TREEFAM_ID | TF316913 |
| | | | UniProt_GCRP | UniProtAcc | Q21446 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | lin |
| | Reference_allele | WBVar00089301 |
| | | WBVar00089587 |
| | Allele (337) |
| | Legacy_information | Class 1 alleles (loss-of-function) n526n540ird : precocious heterochronic lineage alterations in ectoderm; abnormal development of vulva endoderm and mesoderm; abnormal cuticle formation; ES2; male more severely affected only three molts gonadal development abnormal. Similar phenotype in n536n540/Df. NA > 10 (n179ts etc.; also Class 1a n355n679ird ts (only early events precocious); Class 1b n360ts (only late events precocious). Class 2 alleles (gain-of-function) n536sd : retarded heterochronic alterations in many lineages abnormal vulval development cuticle formation supernumerary molts extra divisions in sex mesoblasts intestine etc.; gonadal lineages normal. ES3. ME0? NA2 (n355sd). For both Class 1 and Class 2 mutations late lineages are less affected if animal develops via dauer stage. |
| | | See also n179, n355, n360, n407, n530, n531, n532, n534, n535, n536, n539, n540, n679, n726, n727, n837, n838, n839, n840, n841, n842 |
| | | [C.elegansII] n526n540ird : lf allele (Class II, a-b-), precocious heterochronic lineage alterations in ectoderm; abnormal development of vulva,endoderm and mesoderm; abnormal cuticle formation; precocious dauer entry at L1 molt; ES2; male more severely affected, only three molts, gonadal development abnormal. Similar phenotype in n536n540/Df. OA>10: n179ts, etc.; also n355n679ird,ts (Class V, a-b+, only early events precocious); n360ts(Class III, a+b-, only late events precocious). Also gain-of-function alleles: n536sd (Class I, retarded heterochronic alterations in many lineages; abnormal vulval development, cuticle formation, supernumerary molts, extra divisions in sex mesoblasts, intestine etc.; gonadal lineages normal. ES3), n355sd(similar). Numerous intragenic revertants. For both lf and gf mutations, late lineages are less affected if animal develops via dauer stage. Cloned: two 3.5 kb transcripts, differing 5',encoding 70 kD novel proteins; antibodies stain nuclei; protein levels high in L1, reduced or absent later. Gain-of-function mutations affect3' UTR. [Ruvkun and Giusto 1989; Wightman et al. 1993; GR; VT] |
| | Strain (20) |
| | RNASeq_FPKM | WBls:0000002 (85) |
| | | WBls:0000003 (11) |
| | | WBls:0000004 (43) |
| | | WBls:0000006 | 0.00883236 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000006.Hermaphrodite.WBbt:0007833.SRP042619.SRX559705 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000006.Hermaphrodite.WBbt:0007833.SRP042619.SRX559706 |
| | | WBls:0000007 | 0.00794278 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP045110.SRX666565 |
| | | | 0.0136204 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP045110.SRX666567 |
| | | | 0.0514844 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP042619.SRX559707 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP042619.SRX559708 |
| | | | 0.127276 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0006770.SRP045110.SRX666568 |
| | | | 0.250892 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP029448.SRX343218 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP029448.SRX343219 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP045110.SRX666563 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0006770.SRP045110.SRX666564 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0006770.SRP045110.SRX666566 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP029448.SRX343215 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP029448.SRX343216 |
| | | WBls:0000008 | 0.0759221 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX085219 |
| | | | 0.37494 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX085220 |
| | | | 0.554336 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX145480 |
| | | WBls:0000010 (12) |
| | | WBls:0000013 | 0.0736412 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099986 |
| | | | 0.196171 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022570 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099987 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099996 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099997 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099998 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022571 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX103652 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX103653 |
| | | | 3.49414 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022648 |
| | | | 6.3257 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022604 |
| | | WBls:0000014 (19) |
| | | WBls:0000015 (24) |
| | | WBls:0000017 | 10.7188 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343254 |
| | | | 13.0136 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004458.SRP029448.SRX343277 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0003810.SRP029448.SRX343325 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0008115.SRP029448.SRX343342 |
| | | | 208.46 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004458.SRP029448.SRX343278 |
| | | | 32.3348 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004015.SRP029448.SRX343304 |
| | | | 44.2395 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004015.SRP029448.SRX343305 |
| | | | 71.2452 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343253 |
| | | | 72.6593 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0003810.SRP029448.SRX343324 |
| | | | 82.8112 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343252 |
| | | WBls:0000020 (16) |
| | | WBls:0000021 (20) |
| | | WBls:0000023 | 0.0371712 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000023.Hermaphrodite.WBbt:0007833.SRP015688.SRX185639 |
| | | WBls:0000024 (71) |
| | | WBls:0000027 (15) |
| | | WBls:0000031 | 13.2643 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103277 |
| | | | 24.1532 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103274 |
| | | | 24.9191 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103275 |
| | | | 27.289 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103276 |
| | | | 31.3501 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103273 |
| | | | 37.7809 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX047470 |
| | | | 9.93396 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX008139 |
| | | WBls:0000032 | 11.3631 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX008138 |
| | | | 13.5493 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103984 |
| | | | 30.2427 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103983 |
| | | | 33.4939 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP058023.SRX1019178 |
| | | | 35.2493 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103985 |
| | | | 37.8169 | From_analysis | RNASeq.elegans.WBls:0000032.control_mean |
| | | | | | RNASeq.elegans.WBls:0000032.control_median |
| | | | 42.1399 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP058023.SRX1019179 |
| | | WBls:0000035 (29) |
| | | WBls:0000038 (81) |
| | | WBls:0000041 (28) |
| | | WBls:0000052 | 10.0441 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX037199 |
| | | | 31.6405 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103280 |
| | | | 33.8306 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103278 |
| | | | 34.6698 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103279 |
| | | | 34.706 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103281 |
| | | | 55.7523 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103270 |
| | | | 58.6721 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103269 |
| | | | 5.93572 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX008140 |
| | | | 59.9516 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103271 |
| | | | 61.8583 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103272 |
| | | WBls:0000063 (103) |
| | | WBls:0000064 (14) |
| | | WBls:0000065 (16) |
| | | WBls:0000068 | 4.34655 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265365 |
| | | | 4.407 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265360 |
| | | | 4.55612 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265364 |
| | | | 4.89968 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265362 |
| | | | 5.47301 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265361 |
| | | | 5.57653 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265363 |
| | | WBls:0000131 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343220 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343227 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343228 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343229 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006771.SRP029448.SRX343225 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006771.SRP029448.SRX343226 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343221 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343222 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343223 |
| | | WBls:0000141 | 0.115842 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000141.Hermaphrodite.WBbt:0007833.SRP029448.SRX343161 |
| | | WBls:0000151 | 0.439033 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004015.SRP029448.SRX343280 |
| | | | 0.822498 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004458.SRP029448.SRX343255 |
| | | | 1.69672 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004804.SRP029448.SRX343231 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0003810.SRP029448.SRX343308 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004015.SRP029448.SRX343282 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004458.SRP029448.SRX343257 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004804.SRP029448.SRX343230 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004804.SRP029448.SRX343232 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0007833.SRP029448.SRX343162 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0008115.SRP029448.SRX343326 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0008115.SRP029448.SRX343327 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0008115.SRP029448.SRX343328 |
| | | | 2.2587e-09 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004458.SRP029448.SRX343256 |
| | | | 5.87871 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004015.SRP029448.SRX343281 |
| | | WBls:0000171 | 0.253566 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0007833.SRP029448.SRX343163 |
| | | | 1.61366 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0004458.SRP029448.SRX343259 |
| | | | 1e-10 | From_analysis (13) |
| | | WBls:0000181 | 0.568054 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000181.Hermaphrodite.WBbt:0007833.SRP029448.SRX343164 |
| | | WBls:0000191 | 0.897055 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000191.Hermaphrodite.WBbt:0007833.SRP029448.SRX343165 |
| | | WBls:0000201 | 0.208908 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0004804.SRP029448.SRX343237 |
| | | | 0.373324 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0004458.SRP029448.SRX343261 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0003810.SRP029448.SRX343312 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0003810.SRP029448.SRX343313 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0004015.SRP029448.SRX343287 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0004015.SRP029448.SRX343288 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0004458.SRP029448.SRX343262 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0004458.SRP029448.SRX343263 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0004804.SRP029448.SRX343236 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0004804.SRP029448.SRX343238 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0008115.SRP029448.SRX343331 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0008115.SRP029448.SRX343332 |
| | | WBls:0000221 | 0.131945 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004015.SRP029448.SRX343290 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0003810.SRP029448.SRX343314 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0003810.SRP029448.SRX343315 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004015.SRP029448.SRX343291 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343264 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343265 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343266 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004804.SRP029448.SRX343241 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0008115.SRP029448.SRX343333 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0008115.SRP029448.SRX343334 |
| | | WBls:0000231 | 1.49935 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000231.Hermaphrodite.WBbt:0007833.SRP029448.SRX343167 |
| | | WBls:0000251 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004015.SRP029448.SRX343292 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004458.SRP029448.SRX343268 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343242 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343243 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343244 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0007833.SRP029448.SRX343168 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343335 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343336 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343337 |
| | | | 21.5552 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0003810.SRP029448.SRX343317 |
| | | WBls:0000261 | 0.21842 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000261.Hermaphrodite.WBbt:0007833.SRP029448.SRX343169 |
| | | WBls:0000281 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000281.Hermaphrodite.WBbt:0007833.SRP029448.SRX343170 |
| | | WBls:0000291 | 0.180198 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0007833.SRP029448.SRX343171 |
| | | | 0.251543 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004804.SRP029448.SRX343246 |
| | | | 0.26429 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0008115.SRP029448.SRX343339 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0003810.SRP029448.SRX343318 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0003810.SRP029448.SRX343319 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004015.SRP029448.SRX343294 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004015.SRP029448.SRX343295 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004015.SRP029448.SRX343296 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004458.SRP029448.SRX343271 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004458.SRP029448.SRX343272 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004804.SRP029448.SRX343245 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0008115.SRP029448.SRX343338 |
| | | | 7.88434 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004804.SRP029448.SRX343247 |
| | | WBls:0000301 | 0.314985 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000301.Hermaphrodite.WBbt:0007833.SRP029448.SRX343172 |
| | | WBls:0000311 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000311.Hermaphrodite.WBbt:0007833.SRP029448.SRX343173 |
| | | WBls:0000321 | 1.57419 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000321.Hermaphrodite.WBbt:0007833.SRP029448.SRX343174 |
| | | WBls:0000331 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000331.Hermaphrodite.WBbt:0007833.SRP029448.SRX343175 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000331.Hermaphrodite.WBbt:0007833.SRP029448.SRX343176 |
| | | WBls:0000351 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000351.Hermaphrodite.WBbt:0007833.SRP029448.SRX343178 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000351.Hermaphrodite.WBbt:0007833.SRP029448.SRX343179 |
| | | WBls:0000361 | 0.654856 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000361.Hermaphrodite.WBbt:0007833.SRP029448.SRX343180 |
| | | WBls:0000381 | 0.960706 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004015.SRP029448.SRX343297 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0003810.SRP029448.SRX343320 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004015.SRP029448.SRX343299 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004458.SRP029448.SRX343274 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004458.SRP029448.SRX343275 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343248 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343249 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343250 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0008115.SRP029448.SRX343340 |
| | | WBls:0000391 | 0.729837 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000391.Hermaphrodite.WBbt:0007833.SRP029448.SRX343181 |
| | | WBls:0000401 | 3.67089 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000401.Hermaphrodite.WBbt:0007833.SRP029448.SRX343182 |
| | | WBls:0000421 | 0.159775 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000421.Hermaphrodite.WBbt:0007833.SRP029448.SRX343184 |
| | | WBls:0000431 | 0.622362 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000431.Hermaphrodite.WBbt:0007833.SRP029448.SRX343185 |
| | | WBls:0000451 | 2.91729 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000451.Hermaphrodite.WBbt:0007833.SRP029448.SRX343186 |
| | | WBls:0000461 | 2.24816 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000461.Hermaphrodite.WBbt:0007833.SRP029448.SRX343187 |
| | | WBls:0000471 | 0.865368 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343302 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343300 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343301 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004458.SRP029448.SRX343276 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004804.SRP029448.SRX343251 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0007833.SRP029448.SRX343189 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0008115.SRP029448.SRX343341 |
| | | WBls:0000491 | 4.8224 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000491.Hermaphrodite.WBbt:0007833.SRP029448.SRX343191 |
| | | WBls:0000501 | 35.5545 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000501.Hermaphrodite.WBbt:0007833.SRP029448.SRX343192 |
| | | WBls:0000511 | 19.5958 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000511.Hermaphrodite.WBbt:0007833.SRP029448.SRX343194 |
| | | WBls:0000521 | 18.1738 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000521.Hermaphrodite.WBbt:0007833.SRP029448.SRX343195 |
| | | WBls:0000531 | 17.0716 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000531.Hermaphrodite.WBbt:0007833.SRP029448.SRX343197 |
| | | | 30.8778 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000531.Hermaphrodite.WBbt:0007833.SRP029448.SRX343196 |
| | | WBls:0000541 | 40.1268 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000541.Hermaphrodite.WBbt:0007833.SRP029448.SRX343198 |
| | | | 60.6701 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000541.Hermaphrodite.WBbt:0007833.SRP029448.SRX343199 |
| | | WBls:0000551 | 50.4812 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000551.Hermaphrodite.WBbt:0007833.SRP029448.SRX343200 |
| | | WBls:0000561 | 30.2291 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000561.Hermaphrodite.WBbt:0007833.SRP029448.SRX343201 |
| | | WBls:0000581 | 133.457 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000581.Hermaphrodite.WBbt:0007833.SRP029448.SRX343202 |
| | | WBls:0000621 | 563.153 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000621.Hermaphrodite.WBbt:0007833.SRP029448.SRX343203 |
| | | WBls:0000674 | 4.11922 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265371 |
| | | | 4.69716 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265370 |
| | | | 4.84408 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265368 |
| | | | 4.99877 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265366 |
| | | | 5.43781 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265367 |
| | | | 5.73172 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265369 |
| | | WBls:0000676 | 10.7092 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265374 |
| | | | 11.0242 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265375 |
| | | | 11.9715 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265372 |
| | | | 12.415 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265373 |
| | | WBls:0000694 | 567.247 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000694.Hermaphrodite.WBbt:0007833.SRP029448.SRX343205 |
| | | WBls:0000695 | 376.259 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000695.Hermaphrodite.WBbt:0007833.SRP029448.SRX343206 |
| | | WBls:0000696 | 661.611 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000696.Hermaphrodite.WBbt:0007833.SRP029448.SRX343207 |
| | | WBls:0000697 | 858.681 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000697.Hermaphrodite.WBbt:0007833.SRP029448.SRX343208 |
| | | WBls:0000699 | 614.58 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000699.Hermaphrodite.WBbt:0007833.SRP029448.SRX343210 |
| | | WBls:0000700 | 100.373 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000700.Hermaphrodite.WBbt:0007833.SRP029448.SRX343211 |
| | | WBls:0000701 | 182.863 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000701.Hermaphrodite.WBbt:0007833.SRP029448.SRX343212 |
| | | WBls:0000702 | 51.486 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000702.Hermaphrodite.WBbt:0007833.SRP029448.SRX343213 |
| | | WBls:0000703 | 114.997 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000703.Hermaphrodite.WBbt:0007833.SRP029448.SRX343214 |
| | GO_annotation (16) |
| | Ortholog (28) |
| | Structured_description | Concise_description | lin-14 encodes a novel protein whose activity is required for specifying the division timings of a specific group of cells during postembryonic development; lin-14 loss-of-function mutations result in the premature appearance of later larval lineages, while gain-of-function mutations result in reiteration of L1 larval stages lineages; in addition, lin-14 acts as a positive regulator of AVM, PVM, and FLP touch cell development; in regulating developmental timing, lin-14 acts, in part, by positively regulating the activity of lin-28, which encodes a cytoplasmic protein also required for proper developmental timing; at hatching, LIN-14 is detected in the nuclei of blast cells and neurons; later, from the late L1 to adult stages, LIN-14 levels are negatively regulated by translational repression mediated by lin-4, a 22-nt small temporal RNA (stRNA) that is complementary to sequences in the lin-14 3' UTR. | Paper_evidence | WBPaper00000620 |
| | | | | | WBPaper00001137 |
| | | | | | WBPaper00001468 |
| | | | | | WBPaper00001829 |
| | | | | | WBPaper00001848 |
| | | | | | WBPaper00003931 |
| | | | | | WBPaper00005159 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 02 Sep 2005 00:00:00 |
| | | Automated_description | Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and single-stranded DNA binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; regulation of cell fate specification; and regulation of nematode larval development, heterochronic. Located in condensed nuclear chromosome. Expressed in several structures, including QL; QR; neurons; oocyte; and somatic nervous system. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | T25C12.1a |
| | | T25C12.1b |
| | Corresponding_CDS_history | T25C12.1a:wp196 |
| | Corresponding_transcript | T25C12.1a.1 |
| | | T25C12.1b.1 |
| | Other_sequence (11) |
| | Associated_feature (55) |
| | Transcription_factor | WBTranscriptionFactor000395 |
| Experimental_info | RNAi_result (17) |
| | Expr_pattern (13) |
| | Drives_construct | WBCnstr00000926 |
| | | WBCnstr00007336 |
| | | WBCnstr00007627 |
| | | WBCnstr00015030 |
| | | WBCnstr00015050 |
| | | WBCnstr00015780 |
| | | WBCnstr00015781 |
| | | WBCnstr00036292 |
| | Construct_product | WBCnstr00000967 |
| | | WBCnstr00007627 |
| | | WBCnstr00019563 |
| | | WBCnstr00019564 |
| | | WBCnstr00021119 |
| | | WBCnstr00021910 |
| | | WBCnstr00036292 |
| | Regulate_expr_cluster | WBPaper00026952:class_A |
| | | WBPaper00026952:class_B |
| | | WBPaper00026952:class_C |
| | | WBPaper00026952:class_D |
| | | WBPaper00026952:class_E |
| | | WBPaper00026952:class_F |
| | | WBPaper00026952:class_G |
| | | WBPaper00026952:class_H |
| | Antibody | WBAntibody00000046 |
| | | WBAntibody00000337 |
| | | WBAntibody00000338 |
| | | WBAntibody00001031 |
| | | WBAntibody00001569 |
| | | WBAntibody00001873 |
| | Microarray_results (33) |
| | Expression_cluster (173) |
| | Interaction (256) |
| | WBProcess | WBbiopr:00000031 |
| | | WBbiopr:00000057 |
| | | WBbiopr:00000083 |
| Map_info | Map | X | Position | 3.78431 | Error | 0.060767 |
| | Well_ordered |
| | Positive | Inside_rearr | nDf19 |
| | | | yDp8 |
| | | | yDp10 |
| | | Positive_clone | PPE4 |
| | | | T25C12 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | 2_point | 251 |
| | | | 492 |
| | | | 636 |
| | | | 637 |
| | | | 688 |
| | | | 3648 |
| | | | 3652 |
| | | Multi_point (22) |
| | | Pos_neg_data | 3918 |
| | | | 3920 |
| | | | 654 |
| | | | 668 |
| | | | 3155 |
| | | | 294 |
| | | | 1831 |
| | | | 8427 |
| Reference (365) |
| Method | Gene |
