WormBase Tree Display for WBProcess: WBbiopr:00000057
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| WBbiopr:00000057 | Public_name | RNA interference | ||||
|---|---|---|---|---|---|---|
| Summary | RNA interference (RNAi) refers to the silencing of gene expression by the overexpression of RNA molecules. This process is associated with a cellular and nuclear defense mechanism used to combat molecular parasites such as transposons and viruses. In addition, RNA interference has been shown to play a regulatory role in development. Work in C. elegans and other organisms have identified many key regulators and pathways necessary for this process. Specifically, RNAi has been adapted into a tool for the study of gene function; through the use of RNAi, the expression of a target gene can be inhibited by the reverse engineering of a corresponding dsRNA. | |||||
| Other_name | Gene silencing | |||||
| RNAi | ||||||
| Gene inactivation | ||||||
| Post transcriptional gene silencing | ||||||
| Related_topic | Specialisation_of | WBbiopr:00000037 | ||||
| Involved_entity | Gene (27) | |||||
| Expression_cluster | WBPaper00031477:Down_deps-1_vs_WT | Paper_evidence | WBPaper00031477 | |||
| WBPaper00031477:Up_deps-1_vs_WT | Paper_evidence | WBPaper00031477 | ||||
| Interaction (81) | ||||||
| Anatomy_term | WBbt:0005784 | Paper_evidence | WBPaper00031477 | |||
| Associated_with | GO_term | GO:0016246 | ||||
| Pathway | DB_info | Database | WikiPathways | Pathway | WP394 | |
| Remark | "WikiPathways" "Pathway" "WP394" | |||||
| Reference | WBPaper00003670 | |||||
| WBPaper00027057 | ||||||
| WBPaper00031477 | ||||||
| WBPaper00038519 | ||||||
| WBPaper00040098 | ||||||
| WBPaper00046393 |
