WormBase Tree Display for Variation: WBVar00089587

WBVar00089587 Name: Public_name: n536
    Other_name: T25C12.1b.1:c.*298_*904del
      T25C12.1a.1:c.*298_*904del
    HGVSg: CHROMOSOME_X:g.11484565_11485171del
  Sequence_details: SMap: S_parent: Sequence: T25C12
    Flanking_sequences: tttatccaaacctatactgatgtatattgt ttcagttgtttggggccaaatatctatatc
    Mapping_target: T25C12
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00026801
      WBStrain00026802
      WBStrain00026862
      WBStrain00026903
      WBStrain00040207
      WBStrain00040208
      WBStrain00040210
    Laboratory: MT
    Status: Live
  Linked_to: WBVar00089588
    WBVar00089589
    WBVar00089590
    WBVar00089592
  Affects: Gene: WBGene00220093
      WBGene00003003
      WBGene00220094
    Transcript: T25C12.1b.1 VEP_consequence: 3_prime_UTR_variant
        VEP_impact: MODIFIER
        HGVSc: T25C12.1b.1:c.*298_*904del
        cDNA_position: 2043-2649
        Exon_number: 12/12
      T25C12.12 VEP_consequence: transcript_ablation
        VEP_impact: HIGH
        Exon_number: 1/1
      T25C12.11 VEP_consequence: non_coding_transcript_exon_variant
        VEP_impact: MODIFIER
        cDNA_position: 73-?
        Exon_number: 1/1
      T25C12.1a.1 VEP_consequence: 3_prime_UTR_variant
        VEP_impact: MODIFIER
        HGVSc: T25C12.1a.1:c.*298_*904del
        cDNA_position: 2040-2646
        Exon_number: 14/14
  Genetics: Interpolated_map_position: X 3.87852
    Mapping_data: In_2_point: 251
      In_pos_neg_data: 3918
        3920
  Description: Phenotype: WBPhenotype:0000201 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: abnormal cuticle formation Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Semi_dominant: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson712
        Variation_effect: Hypermorph_gain_of_function: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000358 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: extra divisions in sex mesoblasts, intestine etc. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Semi_dominant: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson712
        Variation_effect: Hypermorph_gain_of_function: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0008373 PATO:0000460 Person_evidence: WBPerson261
                Curator_confirmed: WBPerson712
            WBbt:0005772 PATO:0000460 Person_evidence: WBPerson261
                Curator_confirmed: WBPerson712
      WBPhenotype:0000438 Paper_evidence: WBPaper00001144
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: Animals continue past the L4 molt to an L5 stage animal, not to an adult stage. Paper_evidence: WBPaper00001144
            Curator_confirmed: WBPerson712
          Class I, retarded heterochronic alterations in many lineages Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Semi_dominant: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson712
        Dominant: Paper_evidence: WBPaper00001144
          Curator_confirmed: WBPerson712
        Variation_effect: Hypermorph_gain_of_function: Paper_evidence: WBPaper00001144
            Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Ease_of_scoring: ES3_Easy_to_score: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000446 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: supernumerary molts Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Semi_dominant: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson712
        Variation_effect: Hypermorph_gain_of_function: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000699 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: abnormal vulval development Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Semi_dominant: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson712
        Variation_effect: Hypermorph_gain_of_function: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0001228 Paper_evidence: WBPaper00001144
        Curator_confirmed: WBPerson712
        Remark: Animals do not form adult lateral alae. Paper_evidence: WBPaper00001144
            Curator_confirmed: WBPerson712
        Dominant: Paper_evidence: WBPaper00001144
          Curator_confirmed: WBPerson712
        Variation_effect: Hypermorph_gain_of_function: Paper_evidence: WBPaper00001144
            Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000836 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: gonadal lineages normal. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Semi_dominant: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson712
        Variation_effect: Hypermorph_gain_of_function: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0008373 PATO:0000460 Person_evidence: WBPerson261
                Curator_confirmed: WBPerson712
            WBbt:0005772 PATO:0000460 Person_evidence: WBPerson261
                Curator_confirmed: WBPerson712
  Reference: WBPaper00001467
    WBPaper00038224
    WBPaper00014165
    WBPaper00016093
    WBPaper00014557
    WBPaper00001144
    WBPaper00016468
    WBPaper00016349
    WBPaper00014201
  Method: Deletion_allele