WormBase Tree Display for Gene: WBGene00002253

WBGene00002253 SMap: S_parent: Sequence: F40F4
  Identity: Version: 1
    Name: CGC_name: lbp-1 Person_evidence: WBPerson492
      Sequence_name: F40F4.3
      Molecular_name: F40F4.3
        F40F4.3.1
        CE04533
      Other_name: CELE_F40F4.3 Accession_evidence: NDB BX284606
      Public_name: lbp-1
    DB_info: Database: AceView gene XD879
        WormQTL gene WBGene00002253
        WormFlux gene WBGene00002253
        NDB locus_tag CELE_F40F4.3
        Panther gene CAEEL|WormBase=WBGene00002253|UniProtKB=Q20223
          family PTHR22725
        NCBI gene 180616
        RefSeq protein NM_076156.8
        SwissProt UniProtAcc Q20223
        UniProt_GCRP UniProtAcc Q20223
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lbp
    Allele: WBVar01132596
      WBVar01132597
      WBVar01132598
      WBVar01132599
      WBVar01486655
      WBVar02125422
      WBVar01499636
      WBVar02047738
      WBVar01132595
    Strain: WBStrain00037446
    RNASeq_FPKM (74)
    GO_annotation: 00067527
      00067528
      00067529
      00110318
    Ortholog (44)
    Paralog: WBGene00002259 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00002257 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00002260 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00021486 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00002254 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00002256 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00002255 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: lbp-1 encodes a predicted secreted fatty acid binding protein (FABP) that is similar to the Ascaris suum secreted FABP As-p18; by homology, LBP-1 is predicted to function in sequestering or transporting small hydrophobic molecules such as lipids and steroid hormones; an lbp-1::gfp promoter fusion is expressed in the embryo, beginning at gastrulation, in presumptive hypodermal precursors; lbp-1::gfp hypodermal expression continues in hyp7 nuclei through hatching and is then seen only in one ventral cord neuron from the L1 to adult stages; an LBP-1::GFP fusion construct that contains the predicted LBP-1 secretory signal is secreted into the perivitelline fluid prior to hatching. Paper_evidence: WBPaper00003911
          Curator_confirmed: WBPerson1843
          Date_last_updated: 16 Jan 2008 00:00:00
      Automated_description: Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F40F4.3
    Corresponding_transcript: F40F4.3.1
    Other_sequence (73)
    Associated_feature (12)
  Experimental_info: RNAi_result: WBRNAi00102642 Inferred_automatically: RNAi_primary
      WBRNAi00014657 Inferred_automatically: RNAi_primary
      WBRNAi00046865 Inferred_automatically: RNAi_primary
      WBRNAi00088954 Inferred_automatically: RNAi_primary
      WBRNAi00032032 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr6010
      Expr1031327
      Expr1150732
      Expr2013018
      Expr2031250
    Drives_construct: WBCnstr00003451
      WBCnstr00008651
      WBCnstr00020895
      WBCnstr00020905
      WBCnstr00020919
      WBCnstr00020920
      WBCnstr00020921
      WBCnstr00020929
      WBCnstr00021437
      WBCnstr00036358
    Construct_product: WBCnstr00036358
    Microarray_results (13)
    Expression_cluster: WBPaper00005700:secreted_protein
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032031:DConiospora_downregulated_cDNA_12h
      WBPaper00032031:DConiospora_downregulated_cDNA_24h
      WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00032425:down_in_alg-1
      WBPaper00032425:down_in_rde-4
      WBPaper00032425:down_in_zfp-1
      WBPaper00032976:non_compensated_genes
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035926:A.hydrophila_regulated
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_embryo_enriched
      WBPaper00037950:coelomocytes_embryo_SelectivelyEnriched
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038213:E.coli(LF82)_72h_downregulated
      WBPaper00038215:pod-2(RNAi)_regulated
      WBPaper00038289:oocyte_protein
      WBPaper00040990:PA14_upregulated
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044260:1-methylnicotinamide_downregulated
      WBPaper00044260:nicotic-acid_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_upregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046446:rapid-synthesized_YoungAdult
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_upregulated_protein
      WBPaper00046795:starvation_upregulated
      WBPaper00046858:elt-2(RNAi)_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048988:neuron_expressed
      WBPaper00049018:ham-3(RNAi)_downregulated
      WBPaper00049098:heat-induced_hrde-1(tm1200)
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00049905:Age_variant_expression
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPS_upregulated
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00052987:UV_upregulated_xpc-1;csb-1
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:embryo-to-L1_downregulated_WT_SMARTseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_downregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_OP50
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055482:Tunicamycin_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057041:spc-1(cas971)_downregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated
      WBPaper00057161:meg-3(tm4259)_meg-4(ax2026)_downregulated_endo-siRNA_targets
      WBPaper00057162:meg-3_meg-4_downregulated_sRNA
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058678:DAF-12_upregulated_PVD
      WBPaper00058725:sftb-1(cer39)_upregulated
      WBPaper00059224:tph-1(mg280)_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
      WBPaper00059477:hlh-2(RNAi)_regulated
      WBPaper00060084:cco-1(RNAi)_upregulated_lin-40(yth27)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060871:M.humicola-extract_1h_regulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:Body_wall_muscle
      WBPaper00061340:Ciliated_amphid_neuron
      WBPaper00061340:DA
      WBPaper00061340:DB
      WBPaper00061340:DD
      WBPaper00061340:DVC
      WBPaper00061340:DVC_parent
      WBPaper00061340:hmc
      WBPaper00061340:hmc_and_homolog
      WBPaper00061340:hmc_homolog
      WBPaper00061340:Intestinal_and_rectal_muscle
      WBPaper00061340:mu_int_mu_anal
      WBPaper00061340:Neuroblast_ALM_BDU
      WBPaper00061340:Neuroblast_PVC_LUA
      WBPaper00061340:Parent_of_AMsh_URB
      WBPaper00061340:PVQ_parent
      WBPaper00061340:PVR
      WBPaper00061340:XXX
      WBPaper00061340:Z1_Z4
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:chd-7_16664-jmjd-3.1
      WBPaper00061651:Coelomocyte_enriched
      WBPaper00061651:hmc_enriched
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062118:neural-HSF-1_upregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated_germline
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062606:rotenone_upregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00062672:dcp-66(RNAi)_upregulated
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00063930:BRD-1_interacting
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064315:mes-4(bn73)_downregulated_EGCs
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064871:hypoxia_downregulated_F2
      WBPaper00064952:Day1_vs_L4_upregulated_25C
      WBPaper00064952:Day10_vs_L4_upregulated_25C
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065623:72
      WBPaper00065623:103
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day5
      WBPaper00065841:1_2
      WBPaper00065841:7_2
      WBPaper00065841:7_4
      WBPaper00065841:23_0
      WBPaper00065841:38_3
      WBPaper00065841:64_0
      WBPaper00065841:102_0
      WBPaper00065841:110_0
      WBPaper00065841:110_1
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00066005:RAGA-1_degradation_somatic_upregulated
      WBPaper00066085:sin-3(syb2172)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      cgc4386_cluster_6_2
      cgc4489_group_2
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025032:cluster_2
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_F
      WBPaper00026980:intestine_enriched
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00032948:StarveUp2
      WBPaper00035227:heat_shock_regulated
      WBPaper00035873:osm-7_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00040963:TA100_up
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:cluster_2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(23_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (36)
  Map_info: Map: X Position: -10.6531
    Positive: Positive_clone: F40F4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (16)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene