WormBase Tree Display for Gene: WBGene00002260

WBGene00002260 SMap: S_parent: Sequence: T22G5
  Identity: Version: 1
    Name: CGC_name: lbp-8 Person_evidence: WBPerson492
      Sequence_name: T22G5.6
      Molecular_name: T22G5.6
        T22G5.6.1
        CE41159
      Other_name: CELE_T22G5.6 Accession_evidence: NDB BX284605
      Public_name: lbp-8
    DB_info: Database: AceView gene 5O371
        WormQTL gene WBGene00002260
        WormFlux gene WBGene00002260
        NDB locus_tag CELE_T22G5.6
        Panther gene CAEEL|WormBase=WBGene00002260|UniProtKB=O02324
          family PTHR11955
        NCBI gene 188761
        RefSeq protein NM_074043.6
        SwissProt UniProtAcc O02324
        UniProt_GCRP UniProtAcc O02324
        OMIM gene 170715
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lbp
    Allele (17)
    Strain: WBStrain00037906
    RNASeq_FPKM (74)
    GO_annotation (18)
    Ortholog (36)
    Paralog: WBGene00002253
      WBGene00002254
      WBGene00002255 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00002256
      WBGene00002257 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00002258 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00002259 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00021486 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Concise_description: lpb-8 belongs to a family of small intracellular fatty acid binding proteins (FABPs) that includes As-p18, found in the parasitic nematode Ascaris suum; lpb-8 shares 55% identity with bovine heart FABP but only 25% identity with As-p18 and lacks a secretory signal Paper_evidence: WBPaper00003911
          Curator_confirmed: WBPerson324
          Date_last_updated: 09 Aug 2004 00:00:00
      Automated_description: Enables long-chain fatty acid transporter activity and oleic acid binding activity. Involved in long-chain fatty acid transport. Located in lysosome and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 1G; glioblastoma; and pre-eclampsia. Is an ortholog of several human genes including FABP7 (fatty acid binding protein 7); FABP9 (fatty acid binding protein 9); and PMP2 (peripheral myelin protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3068 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3562)
      DOID:0111560 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9117)
      DOID:10283 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3560)
      DOID:10591 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3559)
      DOID:8893 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3560)
  Molecular_info: Corresponding_CDS: T22G5.6
    Corresponding_CDS_history: T22G5.6:wp176
    Corresponding_transcript: T22G5.6.1
    Associated_feature: WBsf978990
      WBsf232844
      WBsf232845
  Experimental_info: RNAi_result: WBRNAi00102906 Inferred_automatically: RNAi_primary
      WBRNAi00019044 Inferred_automatically: RNAi_primary
      WBRNAi00102649 Inferred_automatically: RNAi_primary
      WBRNAi00088961 Inferred_automatically: RNAi_primary
      WBRNAi00053859 Inferred_automatically: RNAi_primary
      WBRNAi00102905 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021090
      Expr1157410
      Expr2013025
      Expr2031257
    Drives_construct: WBCnstr00020108
      WBCnstr00020236
      WBCnstr00036351
    Construct_product: WBCnstr00020108
      WBCnstr00020235
      WBCnstr00020236
      WBCnstr00036351
    Microarray_results (18)
    Expression_cluster (204)
    Interaction (12)
    WBProcess: WBbiopr:00000121
  Map_info: Map: V Position: 5.72065 Error: 0.00307
    Positive: Positive_clone: T22G5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (16)
  Remark: probable errors in exon choice
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene