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WormBase Tree Display for Gene: WBGene00001403

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Name Class

WBGene00001403EvidencePaper_evidenceWBPaper00003411
SMapS_parentSequenceCHROMOSOME_IV
IdentityVersion1
NameCGC_namefbl-1
Sequence_nameF56H11.1
Molecular_name (24)
Other_nameFBLN1Accession_evidenceEMBLAF051401
CELE_F56H11.1Accession_evidenceNDBBX284604
Public_namefbl-1
DB_infoDatabaseAceViewgene4K309
WormQTLgeneWBGene00001403
WormFluxgeneWBGene00001403
NDBlocus_tagCELE_F56H11.1
PanthergeneCAEEL|WormBase=WBGene00001403|UniProtKB=O77469
familyPTHR24039
NCBIgene177788
RefSeqproteinNM_001306946.3
NM_001306950.3
NM_001028066.6
NM_001306947.3
NM_001306948.3
NM_001028065.4
NM_069293.6
NM_001306949.2
SwissProtUniProtAccO77469
TrEMBLUniProtAccA0A061ADQ1
A0A061AKL1
A0A061AIV4
A0A061ACF5
A0A061ACI3
UniProt_GCRPUniProtAccO77469
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfbl
Allele (63)
StrainWBStrain00022622
WBStrain00028706
WBStrain00028707
WBStrain00028708
WBStrain00035944
WBStrain00003953
WBStrain00050790
WBStrain00054900
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (44)
Structured_descriptionConcise_descriptionfbl-1 encodes proteins orthologous to the vertebrate basement membrane protein fibulin; fbl-1 activity is essential for gonad and body morphology, as well as for reproduction; fbl-1 interacts genetically with gon-1 and mig-17, which encode ADAMTS metalloproteases essential for gonad development; the FBL-1C isoform is expressed in anterior and posterior intestinal cells and localizes to the gonad and pharyngeal basement membranes; the FBL-1D isoform is expressed in some head and tail body wall muscle cells.Paper_evidenceWBPaper00003411
WBPaper00003910
WBPaper00005654
WBPaper00024609
WBPaper00024610
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated11 Dec 2014 00:00:00
Automated_descriptionAn extracellular matrix structural constituent. Involved in extracellular matrix organization; positive regulation of locomotion; and protein localization. Located in basement membrane. Expressed in ALM; GLR; basal lamina; hyp7 syncytium; and nerve ring. Is an ortholog of human FBLN1 (fibulin 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF56H11.1a
F56H11.1b
F56H11.1c
F56H11.1d
F56H11.1e
F56H11.1f
F56H11.1g
F56H11.1h
Corresponding_CDS_historyF56H11.1:wp39
F56H11.1c:wp141
Corresponding_transcriptF56H11.1a.1
F56H11.1b.1
F56H11.1c.1
F56H11.1d.1
F56H11.1e.1
F56H11.1f.1
F56H11.1g.1
F56H11.1h.1
Other_sequence (29)
Associated_featureWBsf655044
WBsf655045
WBsf997438
WBsf228843
WBsf228844
Experimental_infoRNAi_resultWBRNAi00062661Inferred_automaticallyRNAi_primary
WBRNAi00048771Inferred_automaticallyRNAi_primary
WBRNAi00116170Inferred_automaticallyRNAi_primary
WBRNAi00027780Inferred_automaticallyRNAi_primary
WBRNAi00048773Inferred_automaticallyRNAi_primary
WBRNAi00015848Inferred_automaticallyRNAi_primary
WBRNAi00110311Inferred_automaticallyRNAi_primary
WBRNAi00018168Inferred_automaticallyRNAi_primary
WBRNAi00048772Inferred_automaticallyRNAi_primary
Expr_pattern (13)
Drives_constructWBCnstr00003660
WBCnstr00011182
WBCnstr00011223
WBCnstr00011224
WBCnstr00011594
WBCnstr00011920
WBCnstr00036967
Construct_productWBCnstr00011182
WBCnstr00011224
WBCnstr00011920
WBCnstr00036967
Microarray_results (40)
Expression_clusterWBPaper00029359_1166
WBPaper00029359_1197
WBPaper00029359_1291
WBPaper00029359_1546
WBPaper00029359_1557
WBPaper00029359_1599
WBPaper00030922:glycosylated_protein
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037682:sma-2_sma-4_upregulated
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:bodywall-muscle_embryo_enriched
WBPaper00037950:bodywall-muscle_embryo_SelectivelyEnriched
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00044260:nicotinc-acid_upregulated
WBPaper00044316:HgCl2_20uM_upregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045417:128Q-huntingtin_upreglated
WBPaper00046024:sleep_upregulated_oscillating
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048952:glucose_induced
WBPaper00048971:daf-16(mgDf50)_upregulated_L1
WBPaper00048988:neuron_expressed
WBPaper00049018:swsn-2.2(RNAi)_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050053:muscle_enriched_Day4
WBPaper00050121:mir-60(n4947)_upregulated
WBPaper00050332:skn-1(RNAi)_downregulated
WBPaper00050468:hlh-30-dependent_Cry5B_regulated
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050903:mir-35-41(nDf50)_25C_downregulated
WBPaper00050990:intestine_enriched
WBPaper00050990:intestine_expressed
WBPaper00051039:ash-2(RNAi)_regulated_intestine
WBPaper00051039:intestine_enriched
WBPaper00051404:alg-1(gk214)_upregulated
WBPaper00051404:alg-2(ok304)_upregulated
WBPaper00052856:Cadmium_regulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053599:female_vs_male_downregulated
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00054192:cold-shock_downregulated
WBPaper00054758:alg-1(gk204)_upregulated
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055482:Tunicamycin_downregulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056161:male_enriched_siRNA
WBPaper00056284:ints-6(t1903)_downregulated
WBPaper00056290:hsp-6(mg585)_downregulated
WBPaper00056290:mdt-15(mg584)_downregulated
WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058691:set-2(bn129)_upregulated
WBPaper00058711:paraquat_downregulated
WBPaper00058711:skn-1(lax188)_upregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058725:sftb-1(cer6)_upregulated
WBPaper00059027:neuron-synapses_enriched
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059566:wdr-23(mac32)_upregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059839:S.maltophilia_regulated
WBPaper00060661:sensory-neuron_depleted
WBPaper00061007:HB101_upregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061040:eat-2(ad1116)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:AIN
WBPaper00061340:ASG_AWA
WBPaper00061340:AWA
WBPaper00061340:AWB
WBPaper00061340:RIS
WBPaper00061405:S.aureus_downregulated_starvation
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:mep-1(ne4629)_upregulated
WBPaper00061527:ifd-1-ifp-1
WBPaper00061527:T16H12.9-kin-9_20752
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:hsf-1(RNAi)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:etr-1(lq61)_downregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00062446:nhr-8(hd117)_downregulated
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064107:lin-35(n745)_downregulated
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064532:pals-25(icb98)_upregulated
WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
WBPaper00064992:Capsaicin_upregulated
WBPaper00064992:heat-shock_upregulated
WBPaper00065086:JU1400_N.ausubeli_regulated
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065086:N2_N.ausubeli_regulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065835:Day5_vs_Day1_downregulated
WBPaper00065841:4_0
WBPaper00065841:4_2
WBPaper00065841:38_1
WBPaper00065841:38_2
WBPaper00065841:38_3
WBPaper00065841:102_0
WBPaper00065841:104_0
WBPaper00065841:119_0
WBPaper00065841:143_0
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00066005:RAGA-1_degradation_somatic_upregulated
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00066232:ash-2(RNAi)_downregulated_WT
cgc4489_group_4
cgc4489_group_8
WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
WBPaper00025141:N2_Expressed_Genes
WBPaper00029437:dcr-1_downregulated
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00034739:N2moreDR1350
WBPaper00035227:heat_shock_regulated
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00035873:osm-8_regulated
WBPaper00037695:WC_5-day
WBPaper00038172:crh-1null_up_regulated
WBPaper00038172:tax-6null_up_regulated
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00038231:Cry5B_1.5-fold_upregulated
WBPaper00038231:Cry5B_2-fold_downregulated
WBPaper00038427:lin-54_embryo_changed
WBPaper00039866:ClassComp_daf-19_downregulated
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_regulated_aging
WBPaper00040858:eQTL_regulated_old
WBPaper00040876:mir-35_downregulated
WBPaper00040963:TA300_up
WBPaper00041002:HF_3d_2.0mM_Up
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041906:I-3690_vs_OP50_3d
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
WBPaper00044091:Bpseudomallei_repressed_2h
WBPaper00044091:Bpseudomallei_repressed_8h
WBPaper00044091:Bpseudomallei_repressed_12h
WBPaper00045263:isp-1(qm150)_downregulated
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00045673:colistin_upregulated
WBPaper00045960:L1-L4-lethargus_upregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00047021:MWCNT_upregulated
WBPaper00047070:N2_starvation_upregulated
WBPaper00047070:xpa-1_UV_downregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00053236:daf-16(mgDF50)_regulated_Starved
WBPaper00053236:Starvation_regulated_N2
WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
WBPaper00057098:SiO2-nanoparticles_upregulated
[cgc6390]:Cluster_B
[cgc6390]:herm_soma-enriched
InteractionWBInteraction000004893
WBInteraction000004894
WBInteraction000004895
WBInteraction000004896
WBInteraction000008676
WBInteraction000008677
WBInteraction000008829
WBInteraction000028649
WBInteraction000029859
WBInteraction000030531
WBInteraction000047677
WBInteraction000047678
WBInteraction000052918
WBInteraction000162306
WBInteraction000162307
WBInteraction000162397
WBInteraction000166990
WBInteraction000167066
WBInteraction000167138
WBInteraction000167139
WBInteraction000169208
WBInteraction000173571
WBInteraction000183862
WBInteraction000217917
WBInteraction000250599
WBInteraction000253312
WBInteraction000261911
WBInteraction000268460
WBInteraction000280624
WBInteraction000315920
WBInteraction000327967
WBInteraction000349538
WBInteraction000355403
WBInteraction000381265
WBInteraction000384075
WBInteraction000385231
WBInteraction000408460
WBInteraction000411339
WBInteraction000432507
WBInteraction000434657
WBInteraction000448668
WBInteraction000456085
WBInteraction000502202
WBInteraction000502203
WBInteraction000502394
WBInteraction000502395
WBInteraction000511831
WBInteraction000511838
WBInteraction000511839
WBInteraction000511843
WBInteraction000514903
WBInteraction000515482
WBInteraction000517479
WBInteraction000517480
WBInteraction000517481
WBInteraction000520829
WBInteraction000523081
WBInteraction000524607
WBInteraction000524608
WBInteraction000538561
WBInteraction000544675
WBInteraction000546336
WBInteraction000550770
WBInteraction000578997
Map_infoMapIVPosition4.30419Error0.002555
PositivePositive_cloneF56H11Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4280
Pseudo_map_position
Reference (28)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene