WormBase Tree Display for Gene: WBGene00001103
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WBGene00001103 | SMap | S_parent | Sequence | W09G12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | dsl-1 | Person_evidence | WBPerson220 | |||||
Sequence_name | W09G12.4 | ||||||||
Molecular_name | W09G12.4 | ||||||||
W09G12.4.1 | |||||||||
CE18343 | |||||||||
Other_name | CELE_W09G12.4 | Accession_evidence | NDB | BX284604 | |||||
Public_name | dsl-1 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | dsl | ||||||||
Allele (22) | |||||||||
Strain | WBStrain00002904 | ||||||||
WBStrain00008055 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00034014 | ||||||||
00034015 | |||||||||
00034016 | |||||||||
00034017 | |||||||||
00034018 | |||||||||
00108253 | |||||||||
00108254 | |||||||||
00108255 | |||||||||
00108256 | |||||||||
00108257 | |||||||||
Ortholog (31) | |||||||||
Paralog | WBGene00002246 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00001104 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00001105 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00001107 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00001108 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00001109 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00023163 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | ||||||
WBGene00021525 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00021513 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | dsl-1 encodes a secreted protein with a single DSL and EGF domain inseries, resembling Delta/LAG-2; DSL-1, with APX-1 and LAG-2, iscollectively required for LIN-12/Notch-mediated lateral signalling duringpostembryonic vulval development; DSL-1, when misexpressed by lag-2sequences, can rescue the larval-lethal and anchor cell phenotypes oflag-2(q420ts); dsl-1(RNAi) animals have abnormal vulvae in a geneticbackground sensitized for lateral signalling defects; dsl-1(ok810)mutants, while viable and fertile, have a 4% penetrant defect in lateralsignaling, which exceeds 13% with apx-1 and lag-2 RNAi; dsl-1 is stronglytranscribed in P6.p cells; SUR-2 regulates dsl-1 along with apx-1 andlag-2; DSL-1 belongs to a nematode-specific family of Delta/LAG-2-likeproteins that includes DSL-2, -3, -5, -6, and -7. | Paper_evidence | WBPaper00006450 | |||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 21 Aug 2006 00:00:00 | ||||||||
Automated_description | Enables Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in extracellular region and membrane. Expressed in several structures, including P6.paa; P6.pap; P6.ppa; P6.ppp; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | W09G12.4 | |||||||
Corresponding_transcript | W09G12.4.1 | ||||||||
Associated_feature | WBsf651642 | ||||||||
WBsf717130 | |||||||||
WBsf717131 | |||||||||
WBsf229751 | |||||||||
Experimental_info | RNAi_result (14) | ||||||||
Expr_pattern | Chronogram1782 | ||||||||
Expr2842 | |||||||||
Expr6863 | |||||||||
Expr10275 | |||||||||
Expr1023005 | |||||||||
Expr1030703 | |||||||||
Expr1158595 | |||||||||
Expr2011105 | |||||||||
Expr2029341 | |||||||||
Drives_construct | WBCnstr00000065 | ||||||||
WBCnstr00003420 | |||||||||
WBCnstr00015222 | |||||||||
WBCnstr00018944 | |||||||||
Microarray_results (19) | |||||||||
Expression_cluster (129) | |||||||||
Interaction (202) | |||||||||
WBProcess | WBbiopr:00000072 | ||||||||
Map_info | Map | IV | Position | -21.0913 | Error | 0.040765 | |||
Positive | Positive_clone | W09G12 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference (15) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |